Results 81 to 90 of about 494,021 (266)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Contribution of Wheat Diversity to Total Factor Productivity in China

open access: yesJournal of Agricultural and Resource Economics, 2008
The impact of wheat diversity on the productivity of wheat in China is examined using total factor productivity (TFP) and an instrumental variable approach.
Songqing Jin   +4 more
doaj   +1 more source

Weed management in cereals with cover crops - do they help of hinder? [PDF]

open access: yes, 2018
Sustainable crop production calls for integrated weed management approaches. Cover crops (CCs) have been studied primarily in the context of soil fertility and soil structure but they might also supplement the weed management toolbox, particularly when ...
Salonen, Jukka
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Interhousehold variability and its effects on seed circulation networks: a case study from northern Cameroon

open access: yesEcology and Society, 2016
We present a detailed ethnographic case study of sorghum seed acquisitions in a smallholder farming society in northern Cameroon. The effects of variability in household demographics and socioeconomic status on observed patterns of seed provisioning are ...
Jean Wencélius   +3 more
doaj   +1 more source

EDITOR'S CHOICE: REVIEW: Trait matching of flower visitors and crops predicts fruit set better than trait diversity [PDF]

open access: yes, 2015
Understanding the relationships between trait diversity, species diversity and ecosystem functioning is essential for sustainable management. For functions comprising two trophic levels, trait matching between interacting partners should also drive ...
Aizen   +45 more
core   +3 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Harnessing crop diversity. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
McCouch SR, Rieseberg LH.
europepmc   +1 more source

Cross-Disciplinary Analysis of the On-Farm Transition from Conventional to Organic Vegetable Production [PDF]

open access: yes, 2008
This farm-scale analysis of the three-year transition to organic from conventional vegetable production tracked the changes in crop, soil, pest and management on two ranches (40 and 47 ha) in the Salinas Valley, California.
Jackson, Louise E.   +5 more
core  

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