Results 121 to 130 of about 6,688,450 (306)

Harnessing human cross-presenting CLEC9A+XCR1+ dendritic cells for immunotherapy

open access: yesFrontiers in Immunology, 2014
Kirsteen eTullett   +6 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Broadening the Scope of an Institutional Repository: The Patent Project [PDF]

open access: yes, 2014
Presentation for the 2014 Cross Timbers Library Collaborative (CTLC) Annual Conference. This presentation a project to include patents into the University of North Texas (UNT) Scholarly Works institutional ...
Waugh, Laura
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Joining Forces to Jumpstart Student Success in Higher Education [PDF]

open access: yes, 2017
Presentation for the 2017 Cross Timbers Library Collaborative Annual Conference. This presentation describes their partnerships with support services and academic departments that have facilitated services for undergraduate and graduate ...
O'Toole, Erin, Monahan, Jo
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Combined Library Services Desk: Round Table Discussion

open access: yes, 2013
Presentation for a round table discussion at the 2013 Cross Timbers Library Collaborative (CTLC) Conference.
Whitmer, Susan   +2 more
core  

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

open access: yes, 2017
Although antigen cross-presentation in dendritic cells (DCs) is critical to the initiation of most cytotoxic immune responses, the intracellular mechanisms and traffic pathways involved are still unclear.
Jeff E. Grotzke   +16 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

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