Results 51 to 60 of about 6,252,002 (304)
Summary: The complement fragment C5a is closely associated with adaptive immune induction in the mucosa. However, the mechanisms that control CD8+ T cell responses by C5a have not been extensively explored.
Sae-Hae Kim +3 more
doaj +1 more source
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Two copies of original drawing. "Merry Xmas and a Happy New Year From Stan Cross and his Family December 1954"; Also available in an electronic version via the internet at: http://nla ...
Cross, Stan, 1888-1977.
core +2 more sources
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Exiting the Outside World for Cross-Presentation [PDF]
How are extracellular proteins cross-presented on MHC class I molecules? In this issue of Immunity, demonstrate that the ER-associated degradation (ERAD) export pathway operates in the phagosomes of dendritic cells and transfers antigens into the MHC class I pathway.
openaire +2 more sources
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy
Immunization of patients with autologous, ex vivo matured dendritic cell (DC) preparations, in order to prime antitumor T-cell responses, is the focus of intense research.
Emily Gwyer Findlay +13 more
doaj +1 more source
Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8+ Dendritic Cells
Apoptotic cell death of Dendritic cells (DCs) is critical for immune homeostasis. Although intrinsic mechanisms controlling DC death have not been fully characterized up to now, experimentally enforced inhibition of DC-death causes various autoimmune ...
Markus Zwick +12 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

