Results 61 to 70 of about 5,824 (190)

South American rattlesnake bite and soft-tissue infection: report of a case

Revista da Sociedade Brasileira de Medicina Tropical, 2000
The case of a man bitten by a South American rattlesnake (Crotalus durissus) and who developed an abscess at the site of the bite is reported. Abcesses are a rare complication of this type of envenoming, possibly due to the lack of a strong cytotoxic ...
Sérgio de A. Nishioka, Miguel T. Jorge, Paulo Vitor P. Silveira, Lindioneza A. Ribeiro   +3 more
doaj  

A Promising Biomolecule Able to Degrade Neutrophil Extracellular Traps: CdcPDE, a Rattlesnake Phosphodiesterase

Toxins, 2023
Neutrophil extracellular traps (NETs) are an important mechanism for defense against pathogens. Their overproduction can be harmful since excessive NET formation promotes inflammation and tissue damage in several diseases.
Isadora Oliveira, Victor Costa, Flávio Veras, Isabela Ferreira, Fernando Cunha, Thiago Cunha, Wuelton Monteiro, Eliane Arantes, Manuela Pucca   +8 more
doaj   +1 more source

Hypotensive Effects of the Crotalus Durissus Cascavella Venom: Involvement of NO [PDF]

Natural Product Communications, 2011
Crotalus durissus cascavella is a snake native of northeastern Brazil. The aim of the study was to investigate the effects of C. d. cascavella venom on rat mean arterial pressure and vascular reactivity in the mesenteric vascular bed.
Janaina S A M, Evangelista, João J F, Evangelista, Inez L, Evangelista, Diva M B, Nojosa, Nilberto R F, Nascimento, Marcellus H L P, Souza, Renata S, Alves, Alice M C, Martins, Maria Elisabete A, Moraes, Helena S A, Monteiro   +9 more
openaire   +2 more sources

Combined Neuroprotective Effects of N,N‐Dimethyltryptamine and Ventral Root Reimplantation Following Spinal Root Avulsion in Rats

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
The ventral root avulsion (VRA) model provides an excellent experimental paradigm for studying injuries at the Central/Peripheral Nervous Systems (CNS/PNS) interface. By physically disconnecting motoneurons (MNs) from the spinal cord surface, VRA induces profound cellular, molecular, and functional deficits with limited spontaneous recovery.
Paola Andrea Caro Aponte, Edison Huertas Montoya, Italo O. Mazali, Alessandra Sussulini, Benedito Barraviera, Rui Seabra Ferreira Jr., Luciana Politti Cartarozzi, Alexandre Leite Rodrigues de Oliveira   +7 more
wiley   +1 more source

Laboratory evaluation of young ovines inoculated with natural or 60co-irradiated Crotalus durissus terrificus venom during hyperimmunization process

Journal of Venomous Animals and Toxins including Tropical Diseases, 2006
Laboratory profile of young ovines was studied in order to evaluate and compare their antiserum production from natural and Cobalt-60 irradiated Crotalus durissus terrificus (C.d.t.) venoms. The parameters analyzed included complete blood count, and urea,
R. S. Ferreira Junior, N. Nascimento, R. Couto, J. B. Alves, D. A. Meira, B. Barraviera   +5 more
doaj   +1 more source

Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite

Macromolecular Chemistry and Physics, Volume 227, Issue 1, 15 January 2026.
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar, Thomas Oliver, Alexander N. Baker   +2 more
wiley   +1 more source

Decoding Severity in Crotalic Snakebite Cases: Findings From a Decade of Cohort Analysis in Brazil

BioMed Research International, Volume 2026, Issue 1, 2026.
Background Crotalic snakebite accidents are a common cause of admission into toxicology units in Brazil, and are associated with substantial morbidity and mortality. Our aim was to analyze clinical and laboratory findings, outcomes, and variables associated with the severity of patients treated for crotalic accidents at a reference center in Brazil ...
Luciana Reis da Silveira, Aloisio Joaquim Freitas Ribeiro, Victor Schulthais Chagas, Patryk Marques da Silva Rosa, Julia Alpino de Castro Silva, Victoria Fialho Baroni Neves, Adebal de Andrade Filho, Milena Soriano Marcolino, Poorani Gurumallesh Prabu   +8 more
wiley   +1 more source

Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Glioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Livia Ramos Santiago, Edgar Alejandro Pinos Tamayo, Daniel Moreira dos Santos, Bonglee Kim, José R. Almeida, Rosy Iara Maciel de Azambuja Ribeiro, Marco Eigenfeld   +6 more
wiley   +1 more source

Afibrinogenemia following snake bite (Crotalus durissus terrificus)

Revista do Instituto de Medicina Tropical de São Paulo, 1988
This paper reports two cases of afibrinogenemia with normal platelet count following Crotalus durissus terrificus, snake bite Both patients presented high output acute renal failure and case two also had increased blood levels of CPK and LDH compatible ...
C. F. S. Amaral, N. A. Rezende, T. M. G. Pedrosa, O. A. da Silva, E. R. P. Pedroso   +4 more
doaj   +1 more source

The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells

Journal of Applied Toxicology, Volume 45, Issue 10, Page 2055-2067, October 2025.
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor, Beric Muller, Lesetja R. Motadi, Lizelle A. Piater   +3 more
wiley   +1 more source