Results 71 to 80 of about 2,839 (189)

Crotoxin-Induced Mice Lung Impairment: Role of Nicotinic Acetylcholine Receptors and COX-Derived Prostanoids

Biomolecules, 2020
Respiratory compromise in Crotalus durissus terrificus (C.d.t.) snakebite is an important pathological condition. Considering that crotoxin (CTX), a phospholipase A2 from C.d.t. venom, is the main component of the venom, the present work investigated the
Marco Aurelio Sartim, Camila O. S. Souza, Cassiano Ricardo A. F. Diniz, Vanessa M. B. da Fonseca, Lucas O. Sousa, Ana Paula F. Peti, Tassia Rafaella Costa, Alan G. Lourenço, Marcos C. Borges, Carlos A. Sorgi, Lucia Helena Faccioli, Suely Vilela Sampaio   +11 more
doaj   +1 more source

A Promising Biomolecule Able to Degrade Neutrophil Extracellular Traps: CdcPDE, a Rattlesnake Phosphodiesterase

Toxins, 2023
Neutrophil extracellular traps (NETs) are an important mechanism for defense against pathogens. Their overproduction can be harmful since excessive NET formation promotes inflammation and tissue damage in several diseases.
Isadora Oliveira, Victor Costa, Flávio Veras, Isabela Ferreira, Fernando Cunha, Thiago Cunha, Wuelton Monteiro, Eliane Arantes, Manuela Pucca   +8 more
doaj   +1 more source

Combined Neuroprotective Effects of N,N‐Dimethyltryptamine and Ventral Root Reimplantation Following Spinal Root Avulsion in Rats

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
The ventral root avulsion (VRA) model provides an excellent experimental paradigm for studying injuries at the Central/Peripheral Nervous Systems (CNS/PNS) interface. By physically disconnecting motoneurons (MNs) from the spinal cord surface, VRA induces profound cellular, molecular, and functional deficits with limited spontaneous recovery.
Paola Andrea Caro Aponte, Edison Huertas Montoya, Italo O. Mazali, Alessandra Sussulini, Benedito Barraviera, Rui Seabra Ferreira Jr., Luciana Politti Cartarozzi, Alexandre Leite Rodrigues de Oliveira   +7 more
wiley   +1 more source

Proteômica e potencial da atividade trombolítica da propriedade desfibrinogenante, in vivo, do veneno da Serpente Amazônica Crotalus durissus ruruima (Houge 1965). [PDF]

, 2008
An electrophoretic analysis, 1 – DE and 2 – DE, were detected of the venom of Crotalus durissus ruruima proteins with molecular masses of ~ 14, 32 and 50 kDA.
Araújo, Thiago Ferreira de
core  

South American rattlesnake bite and soft-tissue infection: report of a case

Revista da Sociedade Brasileira de Medicina Tropical, 2000
The case of a man bitten by a South American rattlesnake (Crotalus durissus) and who developed an abscess at the site of the bite is reported. Abcesses are a rare complication of this type of envenoming, possibly due to the lack of a strong cytotoxic ...
Sérgio de A. Nishioka, Miguel T. Jorge, Paulo Vitor P. Silveira, Lindioneza A. Ribeiro   +3 more
doaj  

Multiple Mononeuropathy following Crotalid Envenomation: A case report [PDF]

Revista da Sociedade Brasileira de Medicina Tropical
A 34-year-old man developed severe envenomation after being bitten by a Crotalus durissus (rattlesnake), which was treated with anticrotalic serum. Three weeks later, the patient reported paresthesia and neuropathic pain in the left hand, which had ...
Antonio Edvan Camelo-Filho, Pedro Lucas Grangeiro de Sá Barreto Lima, Francisco Luciano Honório Barreto Cavalcante, Pedro Vitor Ferreira Rodrigues, Oliver Reiks Miyajima, Pedro Braga-Neto, Paulo Ribeiro Nóbrega   +6 more
doaj   +1 more source

Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite

Macromolecular Chemistry and Physics, Volume 227, Issue 1, 15 January 2026.
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar, Thomas Oliver, Alexander N. Baker   +2 more
wiley   +1 more source

Laboratory evaluation of young ovines inoculated with natural or 60co-irradiated Crotalus durissus terrificus venom during hyperimmunization process

Journal of Venomous Animals and Toxins including Tropical Diseases, 2006
Laboratory profile of young ovines was studied in order to evaluate and compare their antiserum production from natural and Cobalt-60 irradiated Crotalus durissus terrificus (C.d.t.) venoms. The parameters analyzed included complete blood count, and urea,
R. S. Ferreira Junior, N. Nascimento, R. Couto, J. B. Alves, D. A. Meira, B. Barraviera   +5 more
doaj   +1 more source

Decoding Severity in Crotalic Snakebite Cases: Findings From a Decade of Cohort Analysis in Brazil

BioMed Research International, Volume 2026, Issue 1, 2026.
Background Crotalic snakebite accidents are a common cause of admission into toxicology units in Brazil, and are associated with substantial morbidity and mortality. Our aim was to analyze clinical and laboratory findings, outcomes, and variables associated with the severity of patients treated for crotalic accidents at a reference center in Brazil ...
Luciana Reis da Silveira, Aloisio Joaquim Freitas Ribeiro, Victor Schulthais Chagas, Patryk Marques da Silva Rosa, Julia Alpino de Castro Silva, Victoria Fialho Baroni Neves, Adebal de Andrade Filho, Milena Soriano Marcolino, Poorani Gurumallesh Prabu   +8 more
wiley   +1 more source

Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Glioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Livia Ramos Santiago, Edgar Alejandro Pinos Tamayo, Daniel Moreira dos Santos, Bonglee Kim, José R. Almeida, Rosy Iara Maciel de Azambuja Ribeiro, Marco Eigenfeld   +6 more
wiley   +1 more source