South American Rattlesnake (Crotalus durissus spp.) Envenomation in Dogs in the Semiarid Region of Brazil [PDF]
, 2020 Background: South American rattlesnake (Crotalus durissus spp.) envenomation is rarely reported in small animals and livestock in Brazil. Minor swelling at the snakebite site, skeletal muscle, and renal damage, and severe neurological signs characterize
Almeida Pessoa, André Flávio +7 more
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Experimental envenomation with Crotalus durissus terrificus venom in dogs treated with antiophidic serum - part II: laboratory aspects, electrocardiogram and histopathology [PDF]
, 2007 The present work shows laboratory aspects, electrocardiogram and histopathology results during experimental envenomation by Crotalus durissus terrificus in dogs treated with antiophidic serum.
C. B. Laposy +4 more
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Journal of Venomous Animals and Toxins including Tropical Diseases, 2017 Background Snakebite treatment requires administration of an appropriate antivenom that should contain antibodies capable of neutralizing the venom. To achieve this goal, antivenom production must start from a suitable immunization protocol and proper ...
Ricardo Teixeira-Araújo +7 more
doaj +1 more source
Acidentes por serpentes Crotalus durisssus ssp em crianças em Campinas, São Paulo, Brasil [PDF]
, 2002 From January, 1984 to March, 1999, 31 children under 15 y old (ages 1-14 y, median 8 y) were admitted after being bitten by rattlesnakes (Crotalus durissus ssp). One patient was classified as "dry-bite", 3 as mild envenoming, 9 as moderate envenoming and
BARACAT, Emílio Carlos Elias +4 more
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Toxins, 2019 Neuropathic pain is a disease caused by structural and functional plasticity in central and peripheral sensory pathways that produce alterations in nociceptive processing.
Morena Brazil Sant’Anna +5 more
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Toxins, 2018 The Colombian rattlesnake Crotalus durissus cumanensis is distributed in three geographic zones of the country: the Atlantic Coast, the upper valley of the Magdalena River, and the eastern plains of the Colombian Orinoquía. Its venom induces neurological
Juan Carlos Quintana-Castillo +5 more
doaj +1 more source
Bothropic and crotalic venoms: main aspects and derivative products for therapeutic and diagnostic purposes - a brief approach / Venenos botrópicos e crotálicos: principais aspectos e produtos derivados para fins terapêuticos e diagnósticos - uma breve abordagem [PDF]
, 2022 Ophidian accidents, mainly by snakes of the Bothrops and Crotalus genera, are an important public health problem, especially in tropical countries due to the high rate of occurrence and lethality, being considered as a neglected disease and with ...
Carvalho, Maria das Graças +4 more
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Crotoxin-induced behavioral effects in rats.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1997 Crotoxin is the major component of Crotalus durissus terrificus venom. In view of the presence of high-affinity specific binding sites for crotoxin in the brain, the objective of this work was to investigate whether crotoxin induces behavioral effects in the open-field and hole-board tests. Adult male Wistar rats (180-220 g) treated with crotoxin, 100,
Moreira, E. G. +4 more
openaire +2 more sources
Innovative design for a phase 1 trial with intra-patient dose escalation: The Crotoxin study
Contemporary Clinical Trials Communications, 2017 Introduction: Crotoxin has a broad antitumor activity but has shown frequent neurotoxic toxicity. To induce tolerance and limit this toxicity, we propose a new design with intra-patient dose escalation.
Jacques Medioni +5 more
doaj +1 more source
Crotoxin: Novel activities for a classic β-neurotoxin
Toxicon, 2010 Crotoxin, the main toxin of South American rattlesnake (Crotalus durissus terrificus) venom, was the first snake venom protein to be purified and crystallized. Crotoxin is a heterodimeric beta-neurotoxin that consists of a weakly toxic basic phospholipase A(2) and a non-enzymatic, non-toxic acidic component (crotapotin).
Sampaio, Sandra C. +8 more
openaire +3 more sources