Results 81 to 90 of about 1,216 (181)

Crotoxin-induced behavioral effects in rats

, 2014
Crotoxin is the major component of Crotalus durissus terrificus venom. In view of the presence of high-affinity specific binding sites for crotoxin in the brain, the objective of this work was to investigate whether crotoxin induces behavioral effects in
Moreira, E. G., Rosa, GJM, Vassilieff, V. S., Rogero, JR, Nascimento, N.   +4 more
core  

Single-step purification of crotapotin and crotactine from Crotalus durissus terrificus venom using preparative isoelectric focusing

Brazilian Journal of Medical and Biological Research, 1997
We describe the isolation of crotoxin, a presynaptic B-neurotoxin, as well as its subunits B (crotactine) and A (crotapotin) from lyophilized Crotalus durissus terrificus venom by a single-step preparative isoelectric focusing procedure.
A.S. Aguiar, A.R. Melgarejo, C.R. Alves, S. Giovanni-De-Simone   +3 more
doaj   +1 more source

Identification, description and structural analysis of beta phospholipase A2 inhibitors (sbβPLIs) from Latin American pit vipers indicate a binding site region for basic snake venom phospholipases A2

Toxicon: X, 2019
Several snake species possess, in their circulating blood, endogenous PLA2 inhibitors (sbPLIs) with the primary function of natural protection against toxic enzymes from homologous and heterologous venoms.
Consuelo Latorre Fortes-Dias, Carlos Alexandre H. Fernandes, Paula Ladeira Ortolani, Patrícia Cota Campos, L.A. Melo, Liza Figueiredo Felicori, Marcos Roberto M. Fontes   +6 more
doaj   +1 more source

Nature Of The Postsynaptic Action Of Crotoxin At Guinea-pig Diaphragm End-plates.

, 2015
Crotoxin is known to desensitize the nicotinic receptor of Torpedo marmorata and Electrophorus electricus electroplaques. The aim of the present study was to elucidate whether the postsynaptic effect of crotoxin at a mammalian muscle end-plate is also ...
Heluany, N F, Fontana, M D, Brazil, O V
core   +1 more source

Crotoxin alters lymphocyte distribution in rats: Involvement of adhesion molecules and lipoxygenase-derived mediators

, 2008
Crotoxin is the main neurotoxic component of Crotalus durissus terrificus snake venom and modulates immune and inflammatory responses, interfering with the activity of leukocytes.
SUDO-HAYASHI, Lia S., OTTON, Rosemari, Curi, Rui, Vanessa O. Zambelli, Yara Cury, SAMPAIO, Sandra C., Luis R.C. Gonçalves, Maisa S. Della-Casa, CURY, Yara, Adilson S. Alves, Luiz R.G. Britto, ZAMBELLI, Vanessa O., BRITTO, Luiz R. G., ZYCHAR, Bianca C., Sandra C. Sampaio, Karin Greco, Diva D. Spadacci-Morena, Rui Curi, DELLA-CASA, Maisa S., ALVES, Adilson S., Lia S. Sudo-Hayashi, GRECO, Karin, SPADACCI-MORENA, Diva D., Bianca C. Zychar, GONCALVES, Luis R. C., Rosemari Otton   +25 more
core   +1 more source

Conformation of the neurotoxin crotoxin complex and its subunits

Biochemistry, 1979
Crotoxin, the neurotoxin from Crotalus durissus terrificus venom, and its two subunits, crotoxin A and crotoxin B, have been examined by fluorescence and circular dichroism techniques. Model spectra of crotoxin, generated from the expected contributions of the individual subunits, agreed with experimental results only at pH 2, where crotoxin was fully ...
openaire   +3 more sources

The molecular weight of crotoxin [PDF]

Biochemical Journal, 1938
N, Gralén, T, Svedberg
openaire   +2 more sources

Crotoxin-induced behavioral effects in rats.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 1997
Crotoxin is the major component of Crotalus durissus terrificus venom. In view of the presence of high-affinity specific binding sites for crotoxin in the brain, the objective of this work was to investigate whether crotoxin induces behavioral effects in the open-field and hole-board tests. Adult male Wistar rats (180-220 g) treated with crotoxin, 100,
Moreira, E. G., Nascimento, N., Rosa, G. J.M., Rogero, J. R., Vassilieff, V. S.   +4 more
openaire   +2 more sources

Cross-neutralization of the neurotoxicity of Crotalus durissus terrificus and Bothrops jararacussu venoms by antisera against crotoxin and phospholipase A(2) from Crotalus durissus cascavella venom

, 2015
We have previously demonstrated that rabbit antisera raised against crotoxin from Crotalus durissus cascavella venom (cdc-crotoxin) and its PLA(2) (cdc-PLA(2)) neutralized the neurotoxicity of this venom and its crotoxin.
Hyslop, Stephen, Hyslop, S, Marangoni, Sérgio, Randazzo-Moura, Priscila, Beghini, DG, Rodrigues-Simioni, L, Novello, JC, da Cruz-Hofling, MA, Rodrigues-Simioni, Léa, Marangoni, S, Novello, José Camilo, Randazzo-Moura, P, Beghini, Daniela G, da Cruz-Höfling, Maria Alice   +13 more
core   +1 more source

Neuromuscular effects of venoms and crotoxin-like proteins from Crotalus durissus ruruima and Crotalus durissus cumanensis

, 2015
A myographic study was performed to compare the neuromuscular effects of venoms and crotoxin-like proteins from Crotalus durissus ruruima and Crotalus durissus cumanensis in mice phrenic-diaphragm preparation.
Garrido Cavalcante, Walter Luis, Garrido Cavalcante, Walter Luis [UNESP], Marangoni, Sergio, Gallacci, Marcia [UNESP], Gallacci, Marcia, Cavalcante, Walter Luís Garrido, Ponce-Soto, Luis Alberto   +6 more
core   +1 more source