Results 61 to 70 of about 1,959 (214)

Crotalus durissus terrificus venom as a source of antitumoral agents

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
The basic knowledge on neoplasms is increasing quickly; however, few advances have been achieved in clinical therapy against tumors. For this reason, the development of alternative drugs is relevant in the attempt to improve prognosis and to increase ...
MA Soares, PB Pujatti, CL Fortes-Dias, L Antonelli, RG Santos   +4 more
doaj   +1 more source

Isolation, purification, structure elucidation, and antibody recognition of two phospholipases A2 and Crotoxin variation in the venom of the Tamaulipan rattlesnake Crotalus morulus.

Acta Tropica
The venom of six individuals of Crotalus morulus, an unstudied endemic species of Mexico, was analyzed by anti-crotoxin antibodies (anti-rCrotxB and anti-rCrotxAB) obtained from recombinant expression of crotoxin B and of a tandem protein containing both
Miguel Angel Mejía-Sánchez, Samuel Cardoso-Arenas, R. Miranda-Blancas, A. M. Franco-Vásquez, Alejandro Carbajal-Saucedo, T. Olamendi-Portugal, Fernando Zamudio, R. Arreguín-Espinosa, Gerardo Corzo   +8 more
semanticscholar   +1 more source

Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Glioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Livia Ramos Santiago, Edgar Alejandro Pinos Tamayo, Daniel Moreira dos Santos, Bonglee Kim, José R. Almeida, Rosy Iara Maciel de Azambuja Ribeiro, Marco Eigenfeld   +6 more
wiley   +1 more source

An Evaluation of 3‐Rhamnosylquercetin, a Glycosylated Form of Quercetin, against the Myotoxic and Edematogenic Effects of sPLA2 from Crotalus durissus terrificus

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
This paper shows the results of quercitrin effects on the structure and biological activity of secretory phospholipase (sPLA2) from Crotalus durissus terrificus, which is the main toxin involved in the pharmacological effects of this snake venom. According to our mass spectrometry and circular dichroism results, quercetin was able to promote a chemical
Daniela de Oliveira Toyama, Henrique Hessel Gaeta, Marcus Vinícius Terashima de Pinho, Marcelo José Pena Ferreira, Paulete Romoff, Fábio Filippi Matioli, Angelo José Magro, Marcos Roberto de Mattos Fontes, Marcos Hikari Toyama, Kota V. Ramana   +9 more
wiley   +1 more source

Crotalus durissus terrificus crotapotin naturally displays preferred positions for amino acid substitutions

Journal of Venomous Animals and Toxins including Tropical Diseases, 2017
Background Classically, Crotalus durissus terrificus (Cdt) venom can be described, according to chromatographic criteria, as a simple venom, composed of four major toxins, namely: gyroxin, crotamine, crotoxin and convulxin.
Laudicéia Alves de Oliveira, Rui Seabra Ferreira, Benedito Barraviera, Francilene Capel Tavares de Carvalho, Luciana Curtolo de Barros, Lucilene Delazari dos Santos, Daniel Carvalho Pimenta   +6 more
doaj   +1 more source

Ethnopharmacological Significance of Eclipta alba (L.) Hassk. (Asteraceae)

International Scholarly Research Notices, Volume 2014, Issue 1, 2014., 2014
Eclipta alba can be found growing wild in fallow lands of Bangladesh where it is considered as a weed by farmers. Traditional medicinal systems of the Indian subcontinent countries as well as tribal practitioners consider the plant to have diverse medicinal values and use it commonly for treatment of gastrointestinal disorders, respiratory tract ...
Rownak Jahan, Abdullah Al-Nahain, Snehali Majumder, Mohammed Rahmatullah, Jagadananda Ghosh   +4 more
wiley   +1 more source

Neurotoxic And Myotoxic Actions Of Crotoxin-like And Crotalus Durissus Cascavella Whole Venom In The Chick Biventer Cervicis Preparation.

, 2015
Crotoxin from Crotalus durissus cascavella venom was purified by a combination of molecular exclusion chromatography (Superdex 75 column) and HPLC molecular exclusion (Protein Pack 300SW column). Neurotoxic and myotoxic effects from C.
Novello, J C, Marangoni, S, Beghini, Daniela G, da Cruz-Höfling, Maria Alice, Rodrigues-Simioni, Léa, Toyama, M H   +5 more
core   +2 more sources

Prey specificity of predatory venoms

Biological Reviews, Volume 99, Issue 6, Page 2253-2273, December 2024.
ABSTRACT Venom represents a key adaptation of many venomous predators, allowing them to immobilise prey quickly through chemical rather than physical warfare. Evolutionary arms races between prey and a predator are believed to be the main factor influencing the potency and composition of predatory venoms.
Ondřej Michálek, Glenn F. King, Stano Pekár   +2 more
wiley   +1 more source

Crotalus durissus collilineatus Venom Induces TNF‐α and IL‐10 Production in Human Peripheral Blood Mononuclear Cells

International Scholarly Research Notices, Volume 2014, Issue 1, 2014., 2014
Snake venom has been the subject of numerous studies in an attempt to find properties and biological effects that may be beneficial to man. In this study we evaluated in vitro the effects of Crotalus durissus terrificus (Cdt) and Crotalus durissus collilineatus (Cdc) venom in human peripheral blood mononuclear cells (PBMCs).
Camila Bastos Ribeiro, Jéssica Cristina dos Santos, Jacyelle Medeiros Silva, Pedro Henrique Silva de Godoi, Marta Regina Magalhães, Mônica Spadafora-Ferreira, Simone Gonçalves Fonseca, Irmtraut Araci Hoffman Pfrimer, A. El-Shazly, U. Musabak, T. Oshima, T. Pessi   +11 more
wiley   +1 more source

Snake venom toxins: Potential anticancer therapeutics

Journal of Applied Toxicology, Volume 44, Issue 5, Page 666-685, May 2024.
Abstract Snake venom contains a cocktail of compounds dominated by proteins and peptides, which make up the toxin. The toxin components of snake venom attack several targets in the human body including the neuromuscular system, kidney and blood coagulation system and cause pathologies. As such, the venom toxins can be managed and used for the treatment
Benedict C. Offor, Lizelle A. Piater
wiley   +1 more source