Results 61 to 70 of about 1,216 (181)

Effect of Chlorogenic Acid (5‐Caffeoylquinic Acid) Isolated from Baccharis oxyodonta on the Structure and Pharmacological Activities of Secretory Phospholipase A2 from Crotalus durissus terrificus

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
The aim of this paper was to investigate the effect of chlorogenic acid (5‐caffeoylquinic acid, 5CQA), isolated from Baccharis oxyodonta, on the structure and pharmacological effect of secretory phospholipase A2 (sPLA2) from Crotalus durissus terrificus.
Daniela O. Toyama, Marcelo J. P. Ferreira, Paulete Romoff, Oriana A. Fávero, Henrique H. Gaeta, Marcos H. Toyama, Sung-Hoon Kim   +6 more
wiley   +1 more source

In vivo and in vitro prospection of the anti-ophidic properties exercised by the extracts of Jacaranda decurrens L.

Acta Scientiarum: Biological Sciences, 2021
The research and development of alternative treatments for snakebites (e.g., medicinal plants) is necessary due to the high costs of the existing ones.
Marcus Vinícius Cardoso Trento, Mateus Santos Carapiá, Pedro Henrique Souza César, Mariana Aparecida Braga, Andreimar Martins Soares, Silvana Marcussi   +5 more
doaj   +1 more source

Anti-inflammatory peptides and proteins from venomous snakes: a short review

Journal of Biological Research
Inflammation can be acute or chronic. Chronic inflammation is a condition associated with several diseases like cardiovascular and neurodegenerative disorders, and even cancer.
Fernando Lazcano-Pérez, Adrián Marcelo Franco-Vásquez, Ayetza Mathob Rodríguez-García, Roberto Arreguin-Espinosa   +3 more
doaj   +1 more source

Reduction of crotoxin-induced neuromuscular blockade by gamma radiation

, 1998
A comparative study between crotoxin and gamma irradiated crotoxin was performed on the indirectly evoked twitches and tetani of sciatic nerve-extensor digitorum longus muscle of rats.
Moreira, E. G., Nunes, E. C., Gallacci, M., Vassilieff, V. S., Rogero, JR, Nascimento, N.   +5 more
core   +1 more source

Estudo comparativo da ação da toxina botulínica tipo A e da crotoxina sobre as células satélites da musculatura extrínseca ocular em modelo animal A comparative study of the effects of type A botulinum toxin and crotoxin on satellite cells of extraocular muscles in rabbits

Revista Brasileira de Oftalmologia, 2009
OBJETIVOS: Avaliar o efeito da toxina botulínica do tipo A e da crotoxina na ativação de células satélites das fibras musculares de retos superiores de coelhos.
Marta Halfeld Ferrari Alves Lacordia, Geraldo de Barros Ribeiro, Henderson Celestino de Almeida, Carlos Henrique Reis de Araújo Silva, Maria do Carmo Jordão Coelho, Raul Fernando Binato Lamim   +5 more
doaj   +1 more source

OBTAINMENT OF CROTOXIN/PHEMA-G-LDPE AND CROTOXIN/PCL SYSTEMS

, 2006
A finalidade deste trabalho de pesquisa foi a obtenção de matrizes poliméricas imobilizadas com a crotoxina, proveniente do veneno bruto de cascavel.
Solange Gubbelini Lorenzetti, Lorenzetti, Solange Gubbelini   +1 more
core   +1 more source

A eficácia do antiveneno botrópico-crotálico na neutralização das principais atividades do veneno de Bothrops jararacussu The efficacy of the bothropic/crotalic antivenom on the neutralization of the main Bothrops jararacussu venom activities

Revista do Instituto de Medicina Tropical de São Paulo, 1992
A mionecrose é um dos efeitos causados pelo veneno de Bothrops jararacussu. Uma miotoxina com homologia estrutural à fosfolipase A2 (PLA2), mas sem atividade enzimática, foi isolada desse veneno.
Maria Cristina dos-Santos, Luís Roberto de Camargo Gonçalves, Consuelo L. Fortes-Dias, Yara Cury, José Maria Gutiérrez, Maria de Fátima D. Furtado   +5 more
doaj   +1 more source

Correlating biological activity to thermo-structural analysis of the interaction of CTX with synthetic models of macrophage membranes

Scientific Reports, 2021
The important pharmacological actions of Crotoxin (CTX) on macrophages, the main toxin in the venom of Crotalus durissus terrificus, and its important participation in the control of different pathophysiological processes, have been demonstrated.
Luciana de Araújo Pimenta, Evandro L. Duarte, Gabriel S. Vignoli Muniz, Kerly Fernanda Mesquita Pasqualoto, Marcos Roberto de Mattos Fontes, M. Teresa Lamy, Sandra Coccuzzo Sampaio   +6 more
doaj   +1 more source

Systemic and local myotoxicity induced by snake venom group II phospholipases A(2): Comparison between crotoxin, crotoxin B and a Lys49 PLA(2) homologue

, 2008
The patterns of myotoxicity induced in mice by crotoxin, crotoxin B and a Lys49 phospholipase A(2)(PLA(2)) homologue were compared. Lys49 PLA(2)-induced local myotoxicity is reflected by creatine kinase (CK) loss in injected gastrocnemius muscle, and by ...
Ponce-Soto, LA, Marangoni, Sergio, Marangoni, S, Ponce Soto, Luis Alberto, Gutierrez, JM, Lomonte, B, Lomonte, Bruno, Gutiérrez, José María   +7 more
core   +1 more source

Comparison of crotoxin isoforms reveals that stability of the complex plays a major role in its pharmacological action

, 1993
Crotoxin from the venom of the South American rattlesnake Crotalus durissus terrificus is a potent neurotoxin consisting of a weakly toxic phospholipase-A2 subunit (CB) and a non-enzymic, non-toxic subunit (CA).
Bon, C, Radvanyi, F, Faure, G, Saliou, B, Harvey, A L, Thomson, E   +5 more
core   +3 more sources