Results 51 to 60 of about 690 (160)

Renal and vascular effects of Crotalus durissus cumanensis venom and its crotoxin fraction

Journal of Venomous Animals and Toxins including Tropical Diseases, 2011
In this study, we evaluated the actions of Crotalus durissus cumanensis venom (CDCmV), and its crotoxin (Crtx) fraction, on renal and vascular functions in Wistar rats.
TP Pereira, RRPP Bezerra de Menezes, AFC Torres, TS Brito, FJ Batista-Lima, JFC Vinhote, DF Sousa, RM Ximenes, MH Toyama, EBS Diz Filho, PJC Magalhães, HSA Monteiro, AMC Martins   +12 more
doaj   +1 more source

Prey specificity of predatory venoms

Biological Reviews, Volume 99, Issue 6, Page 2253-2273, December 2024.
ABSTRACT Venom represents a key adaptation of many venomous predators, allowing them to immobilise prey quickly through chemical rather than physical warfare. Evolutionary arms races between prey and a predator are believed to be the main factor influencing the potency and composition of predatory venoms.
Ondřej Michálek, Glenn F. King, Stano Pekár   +2 more
wiley   +1 more source

Crotalus durissus collilineatus Venom Induces TNF‐α and IL‐10 Production in Human Peripheral Blood Mononuclear Cells

International Scholarly Research Notices, Volume 2014, Issue 1, 2014., 2014
Snake venom has been the subject of numerous studies in an attempt to find properties and biological effects that may be beneficial to man. In this study we evaluated in vitro the effects of Crotalus durissus terrificus (Cdt) and Crotalus durissus collilineatus (Cdc) venom in human peripheral blood mononuclear cells (PBMCs).
Camila Bastos Ribeiro, Jéssica Cristina dos Santos, Jacyelle Medeiros Silva, Pedro Henrique Silva de Godoi, Marta Regina Magalhães, Mônica Spadafora-Ferreira, Simone Gonçalves Fonseca, Irmtraut Araci Hoffman Pfrimer, A. El-Shazly, U. Musabak, T. Oshima, T. Pessi   +11 more
wiley   +1 more source

Snake venom toxins: Potential anticancer therapeutics

Journal of Applied Toxicology, Volume 44, Issue 5, Page 666-685, May 2024.
Abstract Snake venom contains a cocktail of compounds dominated by proteins and peptides, which make up the toxin. The toxin components of snake venom attack several targets in the human body including the neuromuscular system, kidney and blood coagulation system and cause pathologies. As such, the venom toxins can be managed and used for the treatment
Benedict C. Offor, Lizelle A. Piater
wiley   +1 more source

Effect of Chlorogenic Acid (5‐Caffeoylquinic Acid) Isolated from Baccharis oxyodonta on the Structure and Pharmacological Activities of Secretory Phospholipase A2 from Crotalus durissus terrificus

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
The aim of this paper was to investigate the effect of chlorogenic acid (5‐caffeoylquinic acid, 5CQA), isolated from Baccharis oxyodonta, on the structure and pharmacological effect of secretory phospholipase A2 (sPLA2) from Crotalus durissus terrificus.
Daniela O. Toyama, Marcelo J. P. Ferreira, Paulete Romoff, Oriana A. Fávero, Henrique H. Gaeta, Marcos H. Toyama, Sung-Hoon Kim   +6 more
wiley   +1 more source

In vivo and in vitro prospection of the anti-ophidic properties exercised by the extracts of Jacaranda decurrens L.

Acta Scientiarum: Biological Sciences, 2021
The research and development of alternative treatments for snakebites (e.g., medicinal plants) is necessary due to the high costs of the existing ones.
Marcus Vinícius Cardoso Trento, Mateus Santos Carapiá, Pedro Henrique Souza César, Mariana Aparecida Braga, Andreimar Martins Soares, Silvana Marcussi   +5 more
doaj   +1 more source

Anti-inflammatory peptides and proteins from venomous snakes: a short review

Journal of Biological Research
Inflammation can be acute or chronic. Chronic inflammation is a condition associated with several diseases like cardiovascular and neurodegenerative disorders, and even cancer.
Fernando Lazcano-Pérez, Adrián Marcelo Franco-Vásquez, Ayetza Mathob Rodríguez-García, Roberto Arreguin-Espinosa   +3 more
doaj   +1 more source

Estudo comparativo da ação da toxina botulínica tipo A e da crotoxina sobre as células satélites da musculatura extrínseca ocular em modelo animal A comparative study of the effects of type A botulinum toxin and crotoxin on satellite cells of extraocular muscles in rabbits

Revista Brasileira de Oftalmologia, 2009
OBJETIVOS: Avaliar o efeito da toxina botulínica do tipo A e da crotoxina na ativação de células satélites das fibras musculares de retos superiores de coelhos.
Marta Halfeld Ferrari Alves Lacordia, Geraldo de Barros Ribeiro, Henderson Celestino de Almeida, Carlos Henrique Reis de Araújo Silva, Maria do Carmo Jordão Coelho, Raul Fernando Binato Lamim   +5 more
doaj   +1 more source

A eficácia do antiveneno botrópico-crotálico na neutralização das principais atividades do veneno de Bothrops jararacussu The efficacy of the bothropic/crotalic antivenom on the neutralization of the main Bothrops jararacussu venom activities

Revista do Instituto de Medicina Tropical de São Paulo, 1992
A mionecrose é um dos efeitos causados pelo veneno de Bothrops jararacussu. Uma miotoxina com homologia estrutural à fosfolipase A2 (PLA2), mas sem atividade enzimática, foi isolada desse veneno.
Maria Cristina dos-Santos, Luís Roberto de Camargo Gonçalves, Consuelo L. Fortes-Dias, Yara Cury, José Maria Gutiérrez, Maria de Fátima D. Furtado   +5 more
doaj   +1 more source

Correlating biological activity to thermo-structural analysis of the interaction of CTX with synthetic models of macrophage membranes

Scientific Reports, 2021
The important pharmacological actions of Crotoxin (CTX) on macrophages, the main toxin in the venom of Crotalus durissus terrificus, and its important participation in the control of different pathophysiological processes, have been demonstrated.
Luciana de Araújo Pimenta, Evandro L. Duarte, Gabriel S. Vignoli Muniz, Kerly Fernanda Mesquita Pasqualoto, Marcos Roberto de Mattos Fontes, M. Teresa Lamy, Sandra Coccuzzo Sampaio   +6 more
doaj   +1 more source