Results 31 to 40 of about 1,216 (181)
Crotoxin Inhibits Endothelial Cell Functions in Two- and Three-dimensional Tumor Microenvironment
Frontiers in Pharmacology, 2021 Antitumor property of Crotoxin (CTX), the major toxin from Crotalus durissus terrificus snake venom, has been demonstrated in experimental animal models and clinical trials.
Ellen Emi Kato +6 more
doaj +1 more source
Crotoxin-induced behavioral effects in rats
, 1996 Crotoxin is the major component of Crotalus durissus terrificus venom. In view of the presence of high-affinity specific binding sites for crotoxin in the brain, the objective of this work was to investigate whether crotoxin induces behavioral effects in
Moreira, E. G. +4 more
core +4 more sources
Crotalic accidents in Brazil: actualities and perspectives
Revista Médica de Minas Gerais, 2022 Introduction: Ophidian accidents are neglected events in tropical and in developing countries, including Brazil. Serpents of the Crotalus genus (rattlesnakes) are those that produce the highest case-fatality in the country.
Hammer, Fernanda Martins +2 more
doaj +1 more source
Toxins, 2020 The most abundant protein families in viper venoms are Snake Venom Metalloproteases (SVMPs), Snake Venom Serine Proteases (SVSPs) and Phospholipases (PLA2s).
Edgar Neri-Castro +9 more
doaj +1 more source
Toxins, 2022 In Colombia, South America, there is a subspecies of the South American rattlesnake Crotalus durissus, C. d. cumanensis, a snake of the Viperidae family, whose presence has been reduced due to the destruction of its habitat. It is an enigmatic snake from
Carlos A. Cañas
doaj +1 more source
Biological and structural characterization of crotoxin and new isoform of crotoxin B PLA(2) (F6a) from Crotalus durissus collilineatus snake venom [PDF]
, 2006 A new crotoxin B isoform PLA(2) (F6a), from Crotalus durissus collilineatus was purified from by one step reverse phase HPLC chromatography using mu-Bondapack C-18 column analytic.
Ponce-Soto, LA +11 more
core +2 more sources
Biological Roles of the Two Components of Crotoxin [PDF]
Proceedings of the National Academy of Sciences, 1971 Crotoxin, the Brazilian rattlesnake neurotoxin, generally behaves as a homogeneous protein; however, it is a molecular complex of an acidic and a basic protein. These can be separated after alkylation or acylation of the amino groups, or on carboxymethyl cellulose at pH 4, or on DEAE-cellulose in 6 M urea. The two proteins differ greatly in composition,
R A, Hendon, H, Fraenkel-Conrat
openaire +2 more sources
The antineoplastic potential of crotoxin isolated from Crotalus durissus terrificus snake venom on oral squamous cell carcinoma [PDF]
, 2023 This study investigated the antineoplastic effects of crotoxin isolated from snake venom of the South American Crotalus durissus terrificus in oral cancer cell lines and in an animal model of chemically induced oral cancer. We analyzed cell viability and
Eliane Macedo Sobrinho Santos +12 more
core +1 more source
BioMed Research International, Volume 2019, Issue 1, 2019., 2019 Snakebite envenoming is a neglected public health issue in many tropical and subtropical countries. To diagnosis and treat snakebites may be challenging to health care personnel since sufficient information has not been yet provided. This review presents the clinical, therapeutic, and laboratory aspects of Crotalus durissus (South American rattlesnakes)
Bruno Tumang Frare +7 more
wiley +1 more source
Molecules, 2020 Crotoxin, from the venom of the South American rattlesnake Crotalus durissus terrificus, is a potent heterodimeric presynaptic β-neurotoxin that exists in individual snake venom as a mixture of isoforms of a basic phospholipase A2 (PLA2) subunit (CBa2 ...
Dorota Nemecz +4 more
doaj +1 more source