Results 171 to 180 of about 1,795 (192)

Induction of tolerance to crotoxin in mice.

The Journal of Pharmacology and Experimental Therapeutics, 1993
Crotoxin, the major toxic component from the venom of Crotalus durissus terrificus is a potent neurotoxin (LD50, i.p., mice, 0.09 mg/kg) which possesses phospholipase A2 activity and causes a blockade of neuromuscular transmission. In this article, we show that mice injected daily with progressively increasing doses of crotoxin develop tolerance to the
M, Okamoto, L J, Viskatis, G, de la Roza, J C, Vidal   +3 more
openaire   +2 more sources

Reduction of crotoxin-induced neuromuscular blockade by gamma radiation

Toxicon, 1998
A comparative study between crotoxin and gamma irradiated crotoxin was performed on the indirectly evoked twitches and tetani of sciatic nerve-extensor digitorum longus muscle of rats. Crotoxin (3 to 14 microg/ml) decreased the amplitude of twitches and induced a slight tetanic fade, and irradiated crotoxin did not significantly affect either twitch ...
Gallacci, M., Nunes, E. C., Moreira, E. G., Nascimento, N., Rogero, JR, Vassilieff, V. S.   +5 more
openaire   +3 more sources

Cytotoxicity of crotoxin on murine erythroleukemia cellsin vitro

Investigational New Drugs, 1993
The cytotoxic effect of crotoxin, a heterodimeric phospholipase A2 from the venom of Crotalus durissus terrificus, was examined on murine erythroleukemia cells in vitro. Crotoxin cytocidal effect on cell growth had an EC50 of approximately 0.1-0.2 microM (3.0-5.0 micrograms/ml) in serum-free medium.
R E, Corin, L J, Viskatis, J C, Vidal, M A, Etcheverry   +3 more
openaire   +2 more sources

Rattlesnake venom neurotoxins: crotoxin-related proteins

1997
Abstract Only two of the neurotoxins from rattlesnake venoms, crotoxin and Mojave toxin, have been characterized to any appreciable extent. These two toxins have very similar structures, comparable activities, and are immunologically crossreactive.
A L Bieber, C Bon,, G Faure
openaire   +1 more source

Crotoxin

Nature, 1939
K. H. SLOTTA, H. FRAENKEL-CONRAT
openaire   +1 more source

Biochemistry and pharmacology of the crotoxin complex

Naunyn-Schmiedebergs Archiv f�r Pharmakologie, 1971
K, Rübsamen, H, Breithaupt, E, Habermann   +2 more
openaire   +2 more sources

Neutralization of crotoxin by the specific crotoxin inhibitor from Crotalus durissus terrificus serum

Toxicon, 1996
G. Faure, J. Perales, C. Villela, V. Choumet, B. Saliou, G.B. Domont, H. Moussatché, C. Bon   +7 more
openaire   +1 more source

Crotoxin: a diaphragm-specific myotoxin?

Toxicon, 1995
G.A. Canziani, M. Langford, L. Viskatis, J.C. Vidal, I. Kaiser   +4 more
openaire   +1 more source

BIOLOGICAL ACTIVITIES OF CROTOXIN AND AMINO ACID SEQUENCE OF CROTOXIN B

1980
H. Fraenkel-Conrat, T-W. Jeng, M. Hsiang
openaire   +1 more source

Electrophoresis of Crotoxin^*

Journal of the American Chemical Society, 1942
Choh Hao Li, H. Fraenkel-Conrat
openaire   +1 more source