Results 181 to 190 of about 1,959 (214)

Muscle necrosis caused by the sub-units of crotoxin

Toxicon, 1986
The effects of the basic (CB) and acidic (CA) subunits of crotoxin on rat skeletal muscle in vivo have been studied. CB caused muscle necrosis, with damage limited to an outer rim of muscle fibres in rat soleus. The inflammatory response was relatively small.
J A, Kouyoumdjian, J B, Harris, M A, Johnson   +2 more
openaire   +2 more sources

Effects of subunit cross-linking on the properties of crotoxin

Toxicon, 1990
Crotoxin was cross-linked using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride. Cross-linked crotoxin had the expected amino-terminal amino acids, amino acid composition, behavior on SDS-PAGE and an 80% reduction of reactable lysine residues.
B W, Lennon, D, Plummer, I I, Kaiser
openaire   +2 more sources

Postsynaptic Effects of Crotoxin and of Its Isolated Subunits

European Journal of Biochemistry, 1979
Crotoxin is a potent neurotoxin from the venom of Crotalus durissus terrificus. It is composed of two subunits: a basic phospholipase A2 with low toxicity (component B) and an acidic protein seemingly devoid of intrinsic biological activity (component A).
C, Bon, J P, Changeux, T W, Jeng, H, Fraenkel-Conrat   +3 more
openaire   +2 more sources

Effects of crotoxin, a neurotoxin from Crotalus durissus terrificus snake venom, on human endothelial cells.

International Journal of Biological Macromolecules, 2019
Vascular endothelium plays an important modulatory role due to the production of molecules that mediate vasomotricity, inflammation, and leukocyte adhesion and rolling.
C. M. D. de Andrade, F. M. Rey, A. Cintra, S. Sampaio, M. R. Torqueti   +4 more
semanticscholar   +1 more source

Crotoxin acceptor protein isolated from Torpedo electric organ: binding properties to crotoxin by surface plasmon resonance

Toxicon, 2003
Crotoxin, a potent neurotoxin from the South American rattlesnake Crotalus durissus terrificus, is a heterodimeric phospholipase A(2) (EC 3.1.1.4), which blocks the release of acetylcholine from peripheral neurons. We previously have suggested the existence of a 48 kDa crotoxin-binding protein in the presynaptic membranes of the electric organ of ...
Grazyna, Faure, Alenka, Copic, Sabine, Le Porrier, Franc, Gubensek, Cassian, Bon, Igor, Krizaj   +5 more
openaire   +2 more sources

Crotoxin

Nature, 1939
K. H. SLOTTA, H. FRAENKEL-CONRAT
openaire   +1 more source

The anti-cancer potential of crotoxin in estrogen receptor-positive breast cancer: its effects and mechanism of action.

Toxicon, 2021
C. Almeida, C. Amaral, T. Augusto, G. Correia-da-Silva, Camila Marques de Andrade, M. R. Torqueti, N. Teixeira   +6 more
semanticscholar   +1 more source

BIOLOGICAL ACTIVITIES OF CROTOXIN AND AMINO ACID SEQUENCE OF CROTOXIN B

1980
H. Fraenkel-Conrat, T-W. Jeng, M. Hsiang
openaire   +1 more source

Neutralization of crotoxin by the specific crotoxin inhibitor from Crotalus durissus terrificus serum

Toxicon, 1996
G. Faure, J. Perales, C. Villela, V. Choumet, B. Saliou, G.B. Domont, H. Moussatché, C. Bon   +7 more
openaire   +1 more source

Antiplasmodial effect of the venom of , crotoxin complex and Crotoxin B

Acta Tropica, 2012
José María Gutiérrez, Cesar Segura, J M Gutierrez   +2 more
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