Results 71 to 80 of about 132,225 (219)

Molecular Simulations of the Ribosome and Associated Translation Factors

open access: yes, 2014
The ribosome is a macromolecular complex which is responsible for protein synthesis in all living cells according to their transcribed genetic information.
Hamed H. Alsulami (532535)   +3 more
core   +6 more sources

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

open access: yesAdvanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu   +3 more
wiley   +1 more source

High‐Resolution Characterization of Protein‐Conjugated, mRNA‐Loaded Lipid Nanoparticles by Analytical Ultracentrifugation

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles containing messenger RNA are characterized by sedimentation velocity analytical ultracentrifugation using UltraScan's new Custom Grid algorithm to provide multi‐dimensional distributions for partial specific volume (particle density), molar mass, sedimentation, diffusion, and hydrodynamic radius.
Sophia Bird   +8 more
wiley   +1 more source

Global structural survey of the flagellotropic myophage φTE infecting agricultural pathogen Pectobacterium atrosepticum

open access: yesNature Communications
Bacteriophages offer a promising alternative to drug-based treatments due to their effectiveness and host specificity. This is particularly important in agriculture as a biocontrol agent of plant diseases.
James Hodgkinson-Bean   +9 more
doaj   +1 more source

3D‐Printed Porous Hydroxyapatite Formed via Enzymatic Mineralization

open access: yesAdvanced Functional Materials, EarlyView.
Bone combines lightness, strength, and the ability to heal, inspiring new materials design. This work introduces a room‐temperature, enzyme‐mediated 3D printing method to create porous hydroxyapatite scaffolds. The process avoids energy‐intensive sintering, preserves bioactivity, and allows control over porosity and mineralization.
Francesca Bono   +6 more
wiley   +1 more source

Electromagnetic lensing using the Aharonov–Bohm effect

open access: yesNew Journal of Physics
We demonstrate theoretically and experimentally an electromagnetic lensing concept using the magnetic vector potential—in a region free of classical electromagnetic fields—via the Aharonov–Bohm (AB) effect.
Makoto Tokoro Schreiber   +3 more
doaj   +1 more source

Mimicking Block Copolymer Self‐Assembly with One‐Pot Synthesized Polyphosphoester Gradient Copolymers

open access: yesAdvanced Functional Materials, EarlyView.
Degradable Polyphosphoester (PPE) gradient copolymers (GCPs) are synthesized via one‐pot copolymerization. We show that GCPs self‐assemble into nanostructures like polymersomes, effectively mimicking the behavior of traditional BCPs. The gradient strength is key, with softer gradients favoring micelles.
Suna Azhdari   +7 more
wiley   +1 more source

Structural insights into the human P2X1 receptor and ligand interactions

open access: yesNature Communications
The P2X1 receptor is a trimeric ligand-gated ion channel that plays an important role in urogenital and immune functions, offering the potential for new drug treatments.
Felix M. Bennetts   +5 more
doaj   +1 more source

Recent advances in retroviruses via cryo-electron microscopy

open access: yesRetrovirology, 2018
Cryo-electron microscopy has undergone a revolution in recent years and it has contributed significantly to a number of different areas in biological research.
Johnson Mak, Alex de Marco
doaj   +1 more source

A^2-Net: Molecular Structure Estimation from Cryo-EM Density Volumes

open access: yes, 2019
Constructing of molecular structural models from Cryo-Electron Microscopy (Cryo-EM) density volumes is the critical last step of structure determination by Cryo-EM technologies.
Li, Hongsheng   +4 more
core   +1 more source

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