Results 41 to 50 of about 22,654 (207)

Bacterial selenocysteine synthase structure revealed by single-particle cryoEM

Current Research in Structural Biology
The 21st amino acid, selenocysteine (Sec), is synthesized on its dedicated transfer RNA (tRNASec). In bacteria, Sec is synthesized from Ser-tRNA[Ser]Sec by Selenocysteine Synthase (SelA), which is a pivotal enzyme in the biosynthesis of Sec.
Vitor Hugo Balasco Serrão, Karine Minari, Humberto D'Muniz Pereira, Otavio Henrique Thiemann   +3 more
doaj   +1 more source

The membrane attack complex, perforin and cholesterol-dependent cytolysin superfamily of pore-forming proteins [PDF]

, 2016
The membrane attack complex and perforin proteins (MACPFs) and bacterial cholesterol-dependent cytolysins (CDCs) are two branches of a large and diverse superfamily of pore-forming proteins that function in immunity and pathogenesis.
Blackman, Bubeck, Bubeck, Cascales, Collier, Czajkowsky, Degiacomi, Dudkina, Dunstone, Estévez-Calvar, Ghatak, Giddings, Gilbert, Gilbert, Gilbert, Gilbert, Giousoh, Hadders, Hadders, Heuck, Hirst, Hotze, Hotze, Hotze, Housden, Jiang, Johnson, Johnson, Kawano, Kondos, LaChapelle, Law, Leka, Leung, Lovelace, Lukoyanova, Marchioretto, McCormack, Menestrina, Merle, Metkar, Morgan, Morgan, Mulvihill, Ounjai, Pardo-López, Peraro, Podack, Podobnik, Popoff, Praper, Ramachandran, Ramachandran, Ramm, Reboul, Reboul, Rosado, Rosado, Rossjohn, Sato, Serna, Seveau, Shatursky, Shepard, Shewell, Sonnen, Sugawara, Taylor, Tilley, Tomita, Tschopp, Tweten, Voskoboinik, Wade, Wade, Walker   +75 more
core   +2 more sources

The stack: a new bacterial structure analyzed in the Antarctic bacterium Pseudomonas deceptionensis M1(T) by transmission electron microscopy and tomography. [PDF]

PLoS ONE, 2013
In recent years, improvements in transmission electron microscopy (TEM) techniques and the use of tomography have provided a more accurate view of the complexity of the ultrastructure of prokaryotic cells. Cryoimmobilization of specimens by rapid cooling
Lidia Delgado, Ornella Carrión, Gema Martínez, Carmen López-Iglesias, Elena Mercadé   +4 more
doaj   +1 more source

Purification and Cryo-electron Microscopy Analysis of Plant Mitochondrial Ribosomes

Bio-Protocol, 2021
Plants make up by far the largest part of biomass on Earth. They are the primary source of food and the basis of most drugs used for medicinal purposes. Similarly to all eukaryotes, plant cells also use mitochondria for energy production.
Florent Waltz, Philippe Giegé, Yaser Hashem   +2 more
doaj   +1 more source

Research progress on the structure and function of the type IX secretion system of Porphyromonas gingivalis

口腔疾病防治, 2023
The Porphyromonas gingivalis type IX secretion system (T9SS) is a recently discovered protein secretion system that is widely distributed in Bacillus cereus. The T9SS is structurally complex and powerful.
ZHANG Ruotong, YE Wei
doaj   +1 more source

Variation in the organization and subunit composition of the mammalian pyruvate dehydrogenase complex E2/E3BP core assembly [PDF]

, 2011
The final version of this article is available at the link below.Crucial to glucose homoeostasis in humans, the hPDC (human pyruvate dehydrogenase complex) is a massive molecular machine comprising multiple copies of three distinct enzymes (E1–E3) and an
Alan Cooper, Blass, Brautigam, Brautigam, Chamberlain, Ciszak, Cooper, David Gilbert, Donna P. McGow, Frank, Hipps, Hiromasa, Hodgson, Hoyer, Huang, Izard, J. Gordon Lindsay, Jones, Jung, Konarev, Laue, Lessard, Leung, Lynch, Mande, Margaret A. Nutley, Mayers, McCartney, Olwyn Byron, Peter Kropholler, Philip Callow, Robinson, Sanderson, Schuck, Semenyuk, Smolle, Stanley, Stoops, Svergun, Swetha Vijayakrishnan, Vijayakrishnan, Wagenknecht, Yu, Zhou, Zhou   +44 more
core   +3 more sources

Cryoelectron microscopy pioneers win chemistry Nobel [PDF]

Physics Today, 2017
Proteins frozen in vitreous ice are now being imaged with atomic resolution.
openaire   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Insights into channel function via channel dysfunction [PDF]

, 2003
The nicotinic synapse has been a touchstone for advances in neuroscience ever since Jean Nicot, the French ambassador to Portugal, sent some tobacco seeds home to Paris in 1550 with a note that the New World plant had interesting effects when smoked. Now
Leite, John F., Lester, Henry A., Rodrigues-Pinguet, Nivalda   +2 more
core  

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source