Results 71 to 80 of about 1,110,843 (197)

Assessing protein‐specific radiation damage in time‐resolved X‐ray solution‐scattering experiments at high‐brilliance synchrotrons using fast detector readout

Acta Crystallographica Section D, Volume 82, Issue 7, Page 715-726, July 2026.
Adenylate kinase was used to quantify how experimental parameters influence radiation damage during time‐resolved X‐ray solution scattering (TR‐XSS) at a multipurpose SAXS beamline. The study provides general guidelines for minimizing radiation artifacts in TR‐XSS.Time‐resolved X‐ray solution scattering (TR‐XSS) enables tracking of protein structural ...
Fatemeh Sabzian-Molaei, Tomás S. Plivelic, Magnus Andersson   +2 more
wiley   +1 more source

Key events in the history of electron microscopy

, 2003
Citation: Haguenau, F. et al. (2003). 'Key events in the history of electron microscopy', Microscopy and Microanalysis, 9(2), 96-138. [Available at http://journals.cambridge.org/action/displayJournal?jid=MAM]. © 2003 Microscopy Society of America.
Haguenau, F., Haguenau, F, Hutchison, John, Simon, GT, Hawkes, PW, Hutchinson, John, Simon, G. T., Williams, DB, Hawkes, P. W., Williams, D. B., Satiat-Jeunemaître, B., Satiat-Jeunemaître, B, Hutchison, JL   +12 more
core   +1 more source

Cryotomography of budding influenza a virus reveals filaments with diverse morphologies that mostly do not bear a genome at their distal end [PDF]

, 2013
Influenza viruses exhibit striking variations in particle morphology between strains. Clinical isolates of influenza A virus have been shown to produce long filamentous particles while laboratory-adapted strains are predominantly spherical.
Swetha Vijayakrishnan, Vijayakrishnan Swetha, Jackson David, Worawit Suphamungmee, David Bhella, Loney Colin, Bhella, D., Swetha Vijayakrishnan (418947), Colin Loney (418948), David Jackson (84936), Frazer J. Rixon (129686), Colin Loney, Suphamungmee Worawit, Rixon, F.J., Jackson, David, Worawit Suphamungmee (418949), Rixon Frazer J., Vijayakrishnan, Swetha, Rixon, Frazer J., Loney, Colin, Bhella David, David Jackson, Loney, C., Suphamungmee, W., Jackson, D., Bhella, David, Vijayakrishnan, S., David Bhella (129684), Suphamungmee, Worawit, Frazer J Rixon   +29 more
core   +1 more source

Cryo-electron Microscopy Analysis of Structurally Heterogeneous Macromolecular Complexes

Computational and Structural Biotechnology Journal, 2016
Cryo-electron microscopy (cryo-EM) has for a long time been a technique of choice for determining structure of large and flexible macromolecular complexes that were difficult to study by other experimental techniques such as X-ray crystallography or ...
Slavica Jonić
doaj   +1 more source

Wave Mechanics of Ciliary Proteins: Quantum‐Enabled Sensing and Energy Transfer in the “Cellular Antenna”

Aggregate, Volume 7, Issue 6, June 2026.
This review surveys eukaryotic cilia as putative quantum‐enabled sensory and regulatory centers. It highlights their multifaceted roles in the cell, focuses on the nontrivial roles of quantum mechanics in their membrane and cytoskeletal proteins, and introduces the essential building blocks enabling quantum properties to survive in the warm, wet, and ...
Daniel L. Bilezikian, Dylan Davidoff, Justin R. Caram, Thomas P. Fay, Aarat P. Kalra, Paul S. Weiss   +5 more
wiley   +1 more source

Interaction of complexes I, III, and IV within the bovine respirasome by single particle cryoelectron tomography [PDF]

, 2011
The respirasome is a multisubunit supercomplex of the respiratory chain in mitochondria. Here we report the 3D reconstruction of the bovine heart respirasome, composed of dimeric complex III and single copies of complex I and IV, at about 2.2-nm ...
Dudkina, N., Kudryashev, M, Dudkina, N.V., Kudryashev, M., Boekema, E. J., Stahlberg, Henning, Stahlberg, H, Dudkina, Natalya V., Natalya V. Dudkina, Egbert J. Boekema, Kudryashev, M. ; https://orcid.org/, Stahlberg, Henning,, Kudryashev, Mikhail, Boekema, E J, Mikhail Kudryashev, Dudkina, Natalya V.,, Dudkina, N V, Boekema, E.J., Dudkina, N. V., Boekema, Egbert J.,, Boekema, E., Stahlberg, H., Kudryashev, Mikhail,, Henning Stahlberg, Boekema, Egbert J.   +24 more
core   +3 more sources

A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex

Cell Reports, 2019
Summary: LSD1 and LSD2 are homologous histone demethylases with opposite biological outcomes related to chromatin silencing and transcription elongation, respectively.
Chiara Marabelli, Biagina Marrocco, Simona Pilotto, Sagar Chittori, Sarah Picaud, Sara Marchese, Giuseppe Ciossani, Federico Forneris, Panagis Filippakopoulos, Guy Schoehn, Daniela Rhodes, Sriram Subramaniam, Andrea Mattevi   +12 more
doaj   +1 more source

Advances in GPCRs Associated With Wnt Signaling Within the Auditory System

Medicine Bulletin, Volume 2, Issue 3, Page 280-298, June 2026.
ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang, Changling Xu, Jiangang Fan, Renjie Chai   +3 more
wiley   +1 more source

Surface topography of microtubule walls decorated with monomeric and dimeric kinesin constructs [PDF]

, 2000
The surface topography of opened-up microtubule walls (sheets) decorated with monomeric and dimeric kinesin motor domains was investigated by freeze-drying and unidirectional metal shadowing.
Mandelkow, Eckhard, Song, Young Hwa, Woehlke, Guenther, Tittmann, Peter, Hoenger, Andreas, Gross, Heinz, Doerhoefer, Monika, Peter Tittmann, Andreas Hoenger, Heinz Gross, Young Hwa Song, Guenther Woehlke, Monika Doerhoefer, Eckhard Mandelkow   +13 more
core   +2 more sources

Rational acquisition of laboratory equipment: an accurate mathematical model to estimate the trade‐offs in shared and nonshared equipment

Acta Crystallographica Section D, Volume 82, Issue 6, Page 638-645, June 2026.
We present a quantitative framework combining cost modelling and queueing theory to estimate hourly access costs, waiting times and congestion levels for shared high‐end scientific equipment. The approach is general, illustrated with cryo‐electron microscopy examples, and implemented in an open‐access online calculator to support evidence‐based ...
C. O. S. Sorzano, J. M. Carazo
wiley   +1 more source