Results 121 to 130 of about 714,192 (184)

Circulating tumor cell parameters during systemic therapy in primary breast cancer

Сибирский онкологический журнал
Circulating tumor cells (CTCs) are frequently studied in terms of their prognostic significance during perioperative systemic therapy (periST) for breast cancer (BC).
I. V. Mikhailov, I. V. Grebennik, A. A. Glazkov, I. A. Kruglova, S. A. Kuznetsova, A. S. Balkanov   +5 more
doaj   +1 more source

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang, Siwen Wu, Yusi Wang, Die Hu, Li Yang   +4 more
wiley   +1 more source

Primary BPH Stromal Cell Cultures Exhibit Heightened Androgen‐Responsiveness

The Prostate, Volume 86, Issue 15, Page 1508-1517, November 2026.
ABSTRACT Background Benign prostatic hyperplasia (BPH) is the most common disease in aging males. BPH growth is androgen‐dependent, and it appears that androgens preferentially stimulate the growth of BPH as compared to normal prostate. The mechanism of preferential androgen stimulation of BPH growth is not clear.
Wei Chen, Fulu Dong, Mohammad Reza Askarpour, Laura E. Pascal, Rajiv Dhir, Uma Chandran, Bruce L. Jacobs, Donald B. DeFranco, Naoki Yoshimura, Zhou Wang   +9 more
wiley   +1 more source

Indium Clusters With 6s2 Lone‐Pair Effect as Excitonic Electron Reservoirs for Direct 2e− Photocatalytic H2O2 Photosynthesis

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
This study demonstrates that indium clusters with 6s2 lone‐pair effect anchored on carbon nitride act as excitonic electron reservoirs to boost charge separation and O2 activation for highly selective direct 2e− oxygen reduction. This work establishes cluster‐mediated electron reservoir engineering as a general strategy for enhancing selective ...
Shijie Xie, Teng Shao, Yuye Jiao, Yurou Song, Huijie Cheng, Yaru Shao, Tianyi Ma, Jungang Hou   +7 more
wiley   +2 more sources

Abstract P2-01-10: Circulating CAF/CTC complexes and breast cancer metastasis

, 2018
Background: Metastatic disease in breast cancer (BC) is the leading cause of cancer-related mortality among women worldwide. Synergy between cancer cells and non-cancer cells of the tumor microenvironment (TME) are vital for disease progression.
C Morata-Tarifa, U Sharma, M Picon-Ruiz, J Slingerland, D El-Ashry, K Medina-Saenz, T Seagroves, M Lippman, P Miller, T Yeasky   +9 more
core   +1 more source

Design, Synthesis and Biophysical Characterisation of CPP‐PNA Conjugates for Targeting Oncogenic microRNA‐221

Journal of Peptide Science, Volume 32, Issue 11, November 2026.
Cell‐penetrating peptide‐peptide nucleic acid (CPP‐PNA) conjugates that target the oncogenic microRNA‐221‐5p were synthesised using Cu(I)‐catalysed azide‐alkyne cycloaddition (CuAAC) and disulfide‐mediated conjugation strategies. These constructs form highly stable, sequence‐selective PNA/RNA heteroduplexes and demonstrate preliminary antiproliferative
Martina Rotondo, Françoise Illien, Fabienne Burlina, Barbara Biondi   +3 more
wiley   +1 more source

In vitro evidence for the potential of EGFR inhibitors to decrease the TGF-β1-induced dispersal of circulating tumour cell clusters mediated by EGFR overexpression

Scientific Reports
Most cancer-related deaths are due to the spread of tumour cells throughout the body—a process known as metastasis. While in the vasculature, these cells are referred to as circulating tumour cells (CTCs) and can be found as either single cells or ...
Jorian D. Hapeman, Rakshit Galwa, Caroline S. Carneiro, Aurora M. Nedelcu   +3 more
doaj   +1 more source

Idiographic interrater reliability measures for intensive longitudinal multirater data

British Journal of Mathematical and Statistical Psychology, Volume 79, Issue 3, Page 547-568, November 2026.
Abstract Interrater reliability plays a crucial role in various areas of psychology. In this article, we propose a multilevel latent time series model for intensive longitudinal data with structurally different raters (e.g., self‐reports and partner reports).
Tobias Koch, Miriam F. Jaehne, Michaela Riediger, Antje Rauers, Jana Holtmann   +4 more
wiley   +1 more source

Investigation of melanoma circulating tumour cell clusters using biomaterial surfaces

, 2023
Circulating tumour cells (CTC) disperse from primary tumours to distal anatomical sites via lymphatic and haematological vessels. This process is known as metastasis, which contributes to the majority of cancer-related mortality.
Rajendran, R
core  

Brain viral reservoir seeding and neurological metabolic dysregulation in early‐life immunodeficiency virus infection

Brain Pathology, Volume 36, Issue 6, November 2026.
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma, Robert Blair, Yao‐Zhong Liu, Xiaolei Wang, Eunice Vincent, Christopher Yu, Lara A. Doyle‐Meyers, Cissy Zhang, Ahmad Saied, Anne Le, Ronald S. Veazey, Qigui Yu, Huanbin Xu   +12 more
wiley   +1 more source