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Cumulative transcription factor binding and p300-mediated histone acetylation drive enhancer activation frequency. [PDF]

open access: yesNat Genet
Baderna V   +11 more
europepmc   +1 more source

Role of CTCF in DNA damage response [PDF]

open access: yesMutation Research - Reviews in Mutation Research, 2019
CCCTC-binding factor (CTCF) is a highly conserved, ubiquitously expressed zinc finger protein. CTCF is a multifunctional protein, associated with a number of vital cellular processes such as transcriptional activation, repression, insulation, imprinting and genome organization.
Suresh Cuddapah   +2 more
exaly   +3 more sources
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Embryogenesis without CTCF in flies and vertebrates

Nature Structural & Molecular Biology, 2021
CTCF is a conserved DNA- and RNA-binding protein with roles in genome folding and transcriptional regulation. Two recent studies investigated how CTCF knockout perturbs genome biology and derails embryogenesis in zebrafish and Drosophila melanogaster, revealing contrasting effects across species.
Geoffrey Fudenberg, Elphège P. Nora
openaire   +2 more sources

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