Applying the Poincaré Disc Method to Analyze the Hierarchical Structure of TADs in Hi-C Data. [PDF]
Timofeev A, Bratchikov A, Anufriev A.
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Cumulative transcription factor binding and p300-mediated histone acetylation drive enhancer activation frequency. [PDF]
Baderna V +11 more
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TM-Loop: Transformer multi-omics hierarchical detection of chromatin loop. [PDF]
Zhai H, Yang H, Hou Z, Liu X, Wang J.
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dcHiChIP: a comprehensive Nextflow-based pipeline for multiscale analysis of chromatin architecture from HiChIP data. [PDF]
Agarwal A, Al Bkhetan Z, Plewczynski D.
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Cohesin-mediated loop extrusion and enhancer-associated factors additively contribute to <i>Sox2</i> looping with its distal enhancer. [PDF]
Martinovic M +7 more
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Guided Electrokinetic Assembly of Functionalized Latex Beads for Fluorescence Signal Enhancement Using AC Electro-Osmosis. [PDF]
Zhou T, Shin A, Kulinsky L.
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Protocol for genomic mapping of chromatin targets using high-throughput CUT&RUN. [PDF]
Kotapalli V, Iakova P, Lu Y, Jain AK.
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Role of CTCF in DNA damage response [PDF]
CCCTC-binding factor (CTCF) is a highly conserved, ubiquitously expressed zinc finger protein. CTCF is a multifunctional protein, associated with a number of vital cellular processes such as transcriptional activation, repression, insulation, imprinting and genome organization.
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Embryogenesis without CTCF in flies and vertebrates
Nature Structural & Molecular Biology, 2021CTCF is a conserved DNA- and RNA-binding protein with roles in genome folding and transcriptional regulation. Two recent studies investigated how CTCF knockout perturbs genome biology and derails embryogenesis in zebrafish and Drosophila melanogaster, revealing contrasting effects across species.
Geoffrey Fudenberg, Elphège P. Nora
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