Results 11 to 20 of about 2,662 (167)
Cthrc1 is a positive regulator of osteoblastic bone formation. [PDF]
PLoS ONE, 2008 Bone mass is maintained by continuous remodeling through repeated cycles of bone resorption by osteoclasts and bone formation by osteoblasts. This remodeling process is regulated by many systemic and local factors.We identified collagen triple helix ...
Hiroaki Kimura +8 more
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Cthrc1, a novel circulating hormone regulating metabolism. [PDF]
PLoS ONE, 2012 We discovered the gene Collagen Triple Helix Repeat Containing 1 (Cthrc1) and reported its developmental expression and induction in adventitial cells of injured arteries and dermal cells of skin wounds. The role of Cthrc1 in normal adult tissues has not
J Patrizia Stohn +4 more
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Application Potential of CTHRC1 as a Diagnostic and Prognostic Indicator for Colon Adenocarcinoma [PDF]
Frontiers in Molecular Biosciences, 2022 Colon adenocarcinoma (COAD), ranking third in incidence and second in mortality, is one of the most common cancer types in the world. The initial stages of COAD usually show no obvious clinical symptoms; moreover, effective screening or diagnostic ...
Chen Pang +3 more
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The Mechanism Of Cthrc1 In The Osteogentic Differentation Of Hpdlscs
International Dental JournalAim or purpose: To investigate the role and underlying mechanisms of collagen triple helix repeat containing 1 (CTHRC1) in the osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs). Materials and methods: 1.
Zhihui Ye, Zhou Rui
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The Role of CTHRC1 in Regulation of Multiple Signaling and Tumor Progression and Metastasis [PDF]
Mediators of Inflammation, 2020 Collagen triple helix repeat containing-1 (CTHRC1) has been identified as cancer-related protein. CTHRC1 expresses mainly in adventitial fibroblasts and neointimal smooth muscle cells of balloon-injured vessels and promotes cell migration and tissue ...
Dan Mei +3 more
doaj +3 more sources
CTHRC1: A New Candidate Biomarker for Improved Rheumatoid Arthritis Diagnosis [PDF]
Frontiers in Immunology, 2019 Background: The purpose of this study was to determine whether plasma levels of the collagen triple helix repeat containing 1 (CTHRC1) protein can serve as a blood-based biomarker for improved diagnosis of rheumatoid arthritis (RA) patients and ...
Askhat Myngbay +9 more
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A Prognostic Signature Constructed by CTHRC1 and LRFN4 in Stomach Adenocarcinoma [PDF]
Frontiers in Genetics, 2021 BackgroundStomach adenocarcinoma (STAD) is the most common histological type of stomach cancer, which causes a considerable number of deaths worldwide. This study aimed to identify its potential biomarkers with the notion of revealing the underlying molecular mechanisms.MethodsGene expression profile microarray data were downloaded from the Gene ...
Songling Han +16 more
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Frontiers in Oncology, 2021 Kidney renal clear cell carcinoma (KIRC) and kidney renal papillary cell carcinoma (KIRP) are the most common RCC types. RCC has high immune infiltration levels, and immunotherapy is currently one of the most promising treatments for RCC. Collagen triple
Fenfang Zhou +13 more
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CTHRC1 is a prognosis-related biomarker correlated with immune infiltrates in colon adenocarcinoma
World Journal of Surgical Oncology, 2022 Background Colon adenocarcinoma (COAD) is one of the common cancers worldwide. Collagen triple helix repeat containing 1 (CTHRC1) has been reported to be involved in cell invasion, angiogenesis, and the promotion of epithelial-mesenchymal transformation ...
Chuang Meng +3 more
doaj +1 more source
Revista de Investigación Clínica, 2023 Background: CTHRC1 is highly expressed in various cancers. Objectives: The aim of the study was to study the role of CTHRC1 played in lung adenocarcinoma (LUAD) development and its underlying biological functions.
Keqi Liu +3 more
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