Results 21 to 30 of about 3,210 (194)
CTHRC1 Derived From Cancer‐Associated Fibroblasts Promotes Pancreatic Cancer Progression and Metastasis via the LIF‐STAT3 Pathway [PDF]
Cancer MedicineBackground Collagen triple helix repeat containing 1 (CTHRC1) is a secreted protein involved in tissue remodeling and fibrotic processes, which also suggests emerging roles in cancer.
Hang Yin +8 more
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CTHRC1-driven breast cancer progression: insights from palmitoylation networks and spatial heterogeneity [PDF]
BMC CancerThis study systematically screened palmitoylation-related key biomarkers in breast cancer and constructed a high-precision diagnostic model combining multi-omics data and machine learning algorithms.
Shujia Yu, Jingyu Wu
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CTHRC1 (Collagen Triple Helix Repeat Containing 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on CTHRC1 (Collagen Triple Helix Repeat Containing 1), with data on DNA, on the protein encoded, and where the gene is implicated.
LeClair, R, Durmus, T, Lindner, V
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Mechanistic study of CTHRC1 in promoting Wilms’ tumor progression by regulating M2-type tumor-associated macrophages polarization [PDF]
Journal of Translational MedicineBackground This study aimed to investigate the role of Collagen triple helix repeat protein 1 (CTHRC1) in Wilms’ tumor (WT) progression and elucidate its molecular mechanism in promoting WT malignancy through regulation of M2-type tumor-associated ...
Yingquan Zhuo +8 more
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A Prognostic Signature Constructed by CTHRC1 and LRFN4 in Stomach Adenocarcinoma [PDF]
Frontiers in Genetics, 2021 BackgroundStomach adenocarcinoma (STAD) is the most common histological type of stomach cancer, which causes a considerable number of deaths worldwide. This study aimed to identify its potential biomarkers with the notion of revealing the underlying molecular mechanisms.MethodsGene expression profile microarray data were downloaded from the Gene ...
Songling Han +16 more
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Frontiers in Oncology, 2021 Kidney renal clear cell carcinoma (KIRC) and kidney renal papillary cell carcinoma (KIRP) are the most common RCC types. RCC has high immune infiltration levels, and immunotherapy is currently one of the most promising treatments for RCC. Collagen triple
Fenfang Zhou +13 more
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HeliyonThe emerging tumor microenvironment (TME) is a complex and constantly evolving entity. Cancer-associated fibroblasts (CAFs) are a vital component of the TME with diverse functions.
Yiding Bian +8 more
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Cthrc1 is a negative regulator of myelination in schwann cells [PDF]
Glia, 2011 AbstractThe analysis of the molecular mechanisms involved in the initial interaction between neurons and Schwann cells is a key issue in understanding the myelination process. We recently identified Cthrc1 (Collagen triple helix repeat containing 1) as a gene upregulated in Schwann cells upon interaction with the axon. Cthrc1 encodes a secreted protein
Apra, Caroline +8 more
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CTHRC1 is a prognosis-related biomarker correlated with immune infiltrates in colon adenocarcinoma
World Journal of Surgical Oncology, 2022 Background Colon adenocarcinoma (COAD) is one of the common cancers worldwide. Collagen triple helix repeat containing 1 (CTHRC1) has been reported to be involved in cell invasion, angiogenesis, and the promotion of epithelial-mesenchymal transformation ...
Chuang Meng +3 more
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Revista de Investigación Clínica, 2023 Background: CTHRC1 is highly expressed in various cancers. Objectives: The aim of the study was to study the role of CTHRC1 played in lung adenocarcinoma (LUAD) development and its underlying biological functions.
Keqi Liu +3 more
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