Results 61 to 70 of about 9,957 (210)

Copper-Catalyzed One-Pot Synthesis of N-Sulfonyl Amidines from Sulfonyl Hydrazine, Terminal Alkynes and Sulfonyl Azides

Molecules, 2021
N-Sulfonyl amidines are developed from a Cu-catalyzed three-component reaction from sulfonyl hydrazines, terminal alkynes and sulfonyl azides in toluene at room temperature.
Yu Zhao, Zitong Zhou, Man Chen, Weiguang Yang   +3 more
doaj   +1 more source

Copper(I)-catalyzed tandem reaction: synthesis of 1,4-disubstituted 1,2,3-triazoles from alkyl diacyl peroxides, azidotrimethylsilane, and alkynes

Beilstein Journal of Organic Chemistry, 2018
A copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction for the synthesis of 1,4-disubstituted 1,2,3-triazoles from alkyl diacyl peroxides, azidotrimethylsilane, and terminal alkynes is reported.
Muhammad Israr, Changqing Ye, Munira Taj Muhammad, Yajun Li, Hongli Bao   +4 more
doaj   +1 more source

Phase transfer agent assisted biphasic CuAAC reaction

RSC Advances, 2014
A phase transfer agent assisted biphasic Cu(I) catalyzed azide–alkyne 1,3-dipolar cycloaddition (CuAAC) reaction system was developed. A biphasic reaction medium consisting of water and an organic solvent ensures the dissolution of reagents and substrates. Tris(triazolylmethyl)amine ligands with an appropriate hydrophilic–lipophilic balance are able to
Jae Hyun Kim, Sanghee Kim
openaire   +1 more source

Solvent-Free Copper-Catalyzed Azide-Alkyne Cycloaddition under Mechanochemical Activation

Molecules, 2015
The ball-mill-based mechanochemical activation of metallic copper powder facilitates solvent-free alkyne-azide click reactions (CuAAC). All parameters that affect reaction rate (i.e., milling time, revolutions/min, size and milling ball number) have been
Laura Rinaldi, Katia Martina, Francesca Baricco, Laura Rotolo, Giancarlo Cravotto   +4 more
doaj   +1 more source

Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies

Molecules, 2015
Copper(I)-catalyzed azide-alkyne cycloaddition, or CuAAC click chemistry, is an efficient method for bioconjugation aiming at chemical and biological applications.
Arindam Maity, Claudia Macaubas, Elizabeth Mellins, Kira Astakhova   +3 more
doaj   +1 more source

Capping Strategies for Covalent Template-Directed Synthesis of Linear Oligomers Using CuAAC.

Journal of the American Chemical Society, 2019
Covalent templating provides an attractive solution to the controlled synthesis of linear oligomers because a template oligomer can be used to define the precise length and sequence of the product.
M. Ciaccia, Diego Núñez-Villanueva, C. Hunter   +2 more
semanticscholar   +1 more source

Stepwise, Protecting Group Free Synthesis of [4]Rotaxanes

Molecules, 2017
Despite significant advances in the last three decades towards high yielding syntheses of rotaxanes, the preparation of systems constructed from more than two components remains a challenge.
James E. M. Lewis, Joby Winn, Stephen M. Goldup   +2 more
doaj   +1 more source

Fluorophore-Assisted Click Chemistry through Copper(I) Complexation

Biomolecules, 2020
The copper-catalyzed alkyne-azide cycloaddition (CuAAC) is one of the most powerful chemical strategies for selective fluorescent labeling of biomolecules in in vitro or biological systems. In order to accelerate the ligation process and ensure efficient
Victor Flon, Magalie Bénard, Damien Schapman, Ludovic Galas, Pierre-Yves Renard, Cyrille Sabot   +5 more
doaj   +1 more source

Synthesis of 1,5-disubstituted tetrazole-1,2,3 triazoles hybrids via Ugi-azide/CuAAC

Synthetic Communications, 2019
A new synthetic strategy to obtain new linked 1,5-disubstituted tetrazole-1,2,3-triazoles via the Ugi-azide reaction followed by a copper-catalyzed alkyne-azide reaction (CuAAC) was developed.
Cesia M. Aguilar-Morales, Denisse de Loera, C. Contreras-Celedón, C. Cortés-García, L. Chacón-García   +4 more
semanticscholar   +1 more source

Intramolecular N···F Pnictogen Bond Mitigates the Explosive Behavior of Azido‐L‐Phenylalanines

ChemistryEurope, EarlyView.
An intramolecular N···F pnictogen bond is the key for the chemical stabilization of the fluorinated azido‐L‐phenylalanines, mitigating the risk of explosion and thus facilitating the handling and storage of these materials. Organic azides are versatile intermediates but are plagued by intrinsic instability and potential explosiveness. Here, it is shown
Andrea Pizzi, Eleonora Veronese, Nicola Demitri, Marco Saccone, Pierangelo Metrangolo, Giancarlo Terraneo   +5 more
wiley   +1 more source