Results 191 to 200 of about 17,883 (244)

Cucurbitacin B Exerts Antiaging Effects in Yeast by Regulating Autophagy and Oxidative Stress. [PDF]

open access: yesOxid Med Cell Longev, 2019
Lin Y   +8 more
europepmc   +1 more source

A Bioreductive Prodrug of Cucurbitacin B Significantly Inhibits Tumor Growth in the 4T1 Xenograft Mice Model. [PDF]

open access: yesACS Med Chem Lett, 2019
Suebsakwong P   +8 more
europepmc   +1 more source

Cucurbitacin B ameliorates acetaminophen induced mitochondrial oxidative stress through the Nrf2 pathway

open access: hybrid
Xin Yang   +8 more
openalex   +1 more source

Cucurbitacin B and cucurbitacin I suppress adipocyte differentiation through inhibition of STAT3 signaling

Food and Chemical Toxicology, 2014
Cucurbitacin B, a member of the cucurbitaceae family, can act as a STAT3 signaling inhibitor to regulate the growth of hepatocellular carcinoma. STAT3 signaling has been shown to inhibit adipocyte differentiation through C/EBPα and PPARγ. Based on these studies, we hypothesized that cucurbitacin B would prevent PPARγ mediated adipocyte differentiation ...
Dong Kwon Yang   +2 more
exaly   +3 more sources

Simultaneous determination of cucurbitacin B and cucurbitacin E in rat plasma by UHPLC-MS/MS: A pharmacokinetics study after oral administration of cucurbitacin tablets

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2017
Cucurbitacin B (CuB) and cucurbitacin E (CuE) are tetracyclic triterpene compounds from Cucurbitaceae, and the main bioactive compounds of cucurbitacins tablets that used to treatment of chronic hepatitis. Pharmacological research has been very comprehensive, and there are few studies on pharmacokinetics, especially about CuE. An Ultra High Performance
Wenbo Zhu, Chun-Juan Yang, Gaosong Wu
exaly   +3 more sources

Cucurbitacin B inhibits the translational expression of hypoxia-inducible factor-1α

European Journal of Pharmacology, 2014
Cucurbitacin B is a triterpenoid compound isolated from Trichosanthes kirilowii Maximowicz, which has been used in oriental medicine for its antitumor activities. However, the mechanisms by which cucurbitacin B inhibits tumor growth are not fully understood.
Juan, Xuejun Jin
exaly   +3 more sources

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