Results 211 to 220 of about 17,883 (244)

Callus formation and cucurbitacin B accumulation in Ecballium elaterium callus cultures

Fitoterapia, 2003
Ecballium elaterium fruit juice is used for the treatment of sinusitis in Turkish folk medicine. The aim of this study was to increase the yield of cucurbitacin B, an anti-inflammatory compound previously isolated in various organs of E. elaterium, through tissue culture techniques.
Yesilada, E, Memisoglu, M, Toker, G, Toker, MC   +3 more
openaire   +3 more sources

Disposition and fate of cucurbitacin B in five species of diabroticites

Journal of Chemical Ecology, 1985
Five species of diabroticites with different host-plant preferences produced an essentially identical array of metabolites when fed radiolabeled cucurbitacin B synthesized in vivo and purified fromCucurbita maxima Duchesne seedlings. All species excreted the bulk of the cucurbitacin (67,17-94.59% total dpm), permanently sequestered a small proportion ...
J E, Ferguson, R L, Metcalf, D C, Fischer   +2 more
openaire   +2 more sources

Combined antitumor activity of cucurbitacin B and docetaxel in laryngeal cancer

European Journal of Pharmacology, 2008
Combination therapy with multiple drugs is a common practice in the treatment of cancer. The promising clinical activity of docetaxel has promoted considerable interest in combining it with other antitumor agents. To determine whether cucurbitacin B can enhance chemosensitivity to docetaxel in laryngeal cancer, in the present study, we investigated the
Tingyan, Liu, Meixia, Zhang, Hongliang, Zhang, Chunyan, Sun, Xiaolin, Yang, Yihui, Deng, Wenyue, Ji   +6 more
openaire   +2 more sources

Cucurbitacin B inhibits immunomodulatory function and the inflammatory response in macrophages

Immunopharmacology and Immunotoxicology, 2015
Cucurbitacin B (CuB) is a triterpenoid that is widely distributed in the plant kingdom and has a variety of biological activities. However, the immunomodulatory and anti-inflammatory effects of CuB have not been well characterized. Therefore, in this study, we investigated the effects of CuB on parameters related to antigen presentation and T-cell ...
Minju, Kim, Sun Young, Park, Mei Ling, Jin, Geuntae, Park, Hong-Joo, Son   +4 more
openaire   +2 more sources

Determination of Cucurbitacin B in Trichosanthes dioica Roxb by HPTLC

Pharmacognosy Communication, 2014
Background: Trichosanthes dioica Roxb, (Cucurbitaceae), is a perennial herb distributed in Asian subcontinent. The pointed gourd is mainly cultivated as a vegetable. The Charaka Samhita prescribes its use in treating jaundice and alcoholism. Ayurvedic literature depicts its use as a diuretic, cardiotoinc, antiulcer and a laxative. Recent research trend
Joy Ashish Solomon, Aditya Ganeshpurkar, Nilesh Shrivastava, Divya Bansal, Nazneen Dubey   +4 more
openaire   +1 more source

Multifaceted Therapeutic Impacts of Cucurbitacin B: Recent Evidences From Preclinical Studies

Phytotherapy Research
ABSTRACTThe most prevalent and bioactive cucurbitacin is Cucurbitacin B (CuB, C32H46O8), which is a tetracyclic triterpene chiefly present in the Cucurbitaceae family. CuB has a wide spectrum of pharmacological properties namely antioxidant, anticancer, hepatoprotective, anti‐inflammatory, antiviral, hypoglycaemic, insecticidal, and neuroprotective ...
Meenal Sahu, Tripti Paliwal, Smita Jain, Kanika Verma, Dipjyoti Chakraborty, Shivangi Jaiswal, Jaya Dwivedi, Swapnil Sharma   +7 more
openaire   +2 more sources

Structure of cucurbitacin B

Tetrahedron Letters, 1960
A. Melera, M. Gut, C.R. Noller
openaire   +1 more source

Cucurbitacin B Δ23-reductase from Cucurbita maxima

Biochimica et Biophysica Acta (BBA) - Enzymology, 1968
J.C. Schabort, D.J.J. Potgieter
openaire   +2 more sources

Cucurbitacin B and Isocucurbitacin B: Cytotoxic Components of Helicteres isora

Journal of Natural Products, 1985
M F, Bean, M, Antoun, D, Abramson, C J, Chang, J L, McLaughlin, J M, Cassady   +5 more
openaire   +2 more sources

Concerning ring A of cucurbitacin B

Tetrahedron Letters, 1960
C.R. Noller, A. Melera, M. Gut, J.N. Shoolery, L.F. Johnson   +4 more
openaire   +1 more source