Results 71 to 80 of about 17,883 (244)

Analysis of Active Compounds Using Target Protein Cofilin―Cucurbitacins in Cytotoxic Plant Bryonia cretica

Toxins, 2022
We examined a two-step target protein binding strategy that uses cofilin as the target protein to analyze the active constituents in Bryonia cretica. In the first step, we prepared the target protein, and used it to analyze the compounds binding to it in
Souichi Nakashima, Yoshimi Oda, Moeko Morita, Ayako Ohta, Toshio Morikawa, Hisashi Matsuda, Seikou Nakamura   +6 more
doaj   +1 more source

Identification of Blood Pressure‐Associated Metabolites by Integrating Metabolomic and Genetic Analysis

MedComm, Volume 7, Issue 4, April 2026.
This study identified 10 potential causality between metabolites and blood pressure and found potential genetic regulators of two metabolites. Multiomics integration revealed that a genetic variant near the omega‐3 metabolism genes (FADS1/FADS2) may influence blood pressure regulation by modulating prostaglandin E3 levels.
Yuanjiao Liu, Chunxiao Cheng, Xiong‐Fei Pan, Wei Shao, Dan Zhou, Yimin Zhu   +5 more
wiley   +1 more source

Comparison of the pharmacokinetic profiles of three triterpenoids after oral administration of a cucurbitacin tablet and nanosuspension by UHPLC-MS/MS

Frontiers in Pharmacology
IntroductionCucurbitacin, a class of triterpenoid compounds isolated from Pedicellus Melo, possesses various biological activities and is the primary active component of cucurbitacin tablets (CUT) used to treat chronic hepatitis and primary liver cancer.
Chun-nan Zhang, Zhi-bin Wang, Rui-tong Du, Shu-lu Zhang, Chu-qiao Wang, Meng Wang, Li-hong Wu, De-qiang Yang, Chen Wang   +8 more
doaj   +1 more source

Glucosinolate hydrolysis products suppress entomopathogenic nematodes in vitro but do not protect sequestering flea beetle larvae in vivo

Pest Management Science, Volume 82, Issue 4, Page 3603-3612, April 2026.
The flea beetle's glucosinolate‐based chemical defense fails to protect larvae from nematode infection. However, the defense inhibits the nematode's symbiotic bacteria, thereby potentially impairing nematode reproduction and biocontrol success. Abstract BACKGROUND The efficacy of entomopathogenic nematodes (EPNs) in the biological control of insect ...
Johannes Körnig, Vojtech Beneš, Christin Manthey, Michael Reichelt, Grit Kunert, Christian Paetz, Johanna Kutzschbach, Paula Lampe, Martin Kaltenpoth, Franziska Beran   +9 more
wiley   +1 more source

Wild edible plants: Nutritional and toxicological characteristics, retrieval strategies and importance for today's society [PDF]

, 2017
Wild edible plants (WEPs) are part of the cultural and genetic heritage of different regions of the world. In times of famine and scarcity, these sources of nutrients and health-promoting compounds have received high importance mainly in rural and ...
Abbasi, Abdelli, Aceituno-Mata, Al-Qura'n, Alarcón, Amaducci, Amalraj, Amirul, Ana Maria Carvalho, Anderson, AOAC, Bacchetta, Baker, Barreira, Barros, Barros, Barros, Barros, Barros, Barros, Barros, Barros, Barros, Barroso, Bianco, Bicho, Brogren, Caldas, Caleja, Caleja, Caleja, Carocho, Carr, Carvalho, Carvalho, Carvalho, Castañeda-Álvarez, Chen, Chen, Chen, Costa, Cowan, Da Rocha, Dias, Dodson, EFSA, EFSA, EFSA, EMA, EMA, European Commission, Fajardo, Fernandes, Galli, García Herrera, García-Herrera, García-Herrera, García-Herrera, García-Jiménez, Gille, Glensk, Gry, Guerra, Guil, Guil-Guerrero, Guil-Guerrero, Guil-Guerrero, Guimarães, Gupta, Güçlü-Üstündağ, Hylands, Hylands, Isabel C.F.R. Ferreira, José Pinela, Kaur, Kaushik, Kemal, Kim, Kiuchi, Kovács, Kovács, Kristanc, Kristanc, Kumarasamy, Lee, Li, Liebman, Magos Brehm, Marostica, Martins, Martins, Martins, Mason, Maxted, Menendez-Baceta, Menendez-Baceta, Molina, Monzote, Morales, Morales, Morales, Morales, Morales, Morales, Muzquiz, Muñoz, Niki, Niki, Nikolić, Oda, Oliveira, Oobayashi, Ottaway, Otten, Palaniswamy, Pandey, Pardo-de-Santayana, Pereira, Pereira, Pereira, Petropoulos, Petropoulos, Pinela, Pinela, Pinela, Pinela, Pinela, Pinela, Pinela, Pinela, Podolak, Pohlmann, Quintaes, Radulović, Ranfa, Renna, Reyes-García, Roeder, Réthy, Saini, Schippmann, Simopoulos, Sinha, Smith, Smolarz, Smolin, Souci, Stein, Street, Swaminathan, Sánchez-Mata, Sánchez-Mata, Sõukand, Sõukand, Tardio, Tardío, Tardío, Tardío, Tardío, Teixeira, The European Parliment and the Council of the European Union, The Plant List, Thomassen, Torbati, Torija-Isasa, Trichopoulou, Tucker, Turner, Tuttolomondo, Vacillotto, Vasquez, Vermerris, Vermerris, Vinha, Vizgirdas, Wiedenfeld, Wretensjö, Wu, Zhang, Zhang, Zhao, Łuczaj, Łuczaj, Żołnierczyk   +183 more
core   +1 more source

Isolation of anticancer constituents from Cucumis prophetarum var. prophetarum through bioassay-guided fractionation

BMC Complementary and Alternative Medicine, 2018
Background Cucumis prophetarum var. prophetarum is used in Saudi folk medicine for treating liver disorders and grows widely between Abha and Khamis Mushait City, Saudi Arabia.
Abdulrhman Alsayari, Lucas Kopel, Mahmoud Salama Ahmed, Hesham S. M. Soliman, Sivakumar Annadurai, Fathi T. Halaweish   +5 more
doaj   +1 more source

Convergence and parallelism in the evolution of plant metabolism

Journal of Integrative Plant Biology, Volume 68, Issue 4, Page 1013-1031, April 2026.
Similar traits in different organisms may originate from shared ancestry or evolve independently. The terminology used to define phenotypic similarity is often confusing. This review attempts to clarify the definitions and present examples from plant domestication and specialized metabolism to explain how complex traits evolve repeatedly in plants ...
Federico Scossa, Mustafa Bulut, Thomas Naake, John C. D'Auria, Alisdair R. Fernie   +4 more
wiley   +1 more source

Depletion of ATP-citrate lyase (ATPCL) affects chromosome integrity without altering histone acetylation in Drosophila mitotic cells [PDF]

, 2019
The Citrate Lyase (ACL) is the main cytosolic enzyme that converts the citrate exported from mitochondria by the SLC25A1 carrier in Acetyl Coenzyme A (acetyl-CoA) and oxaloacetate.
CENCI, GIOVANNI, DI GIORGIO, MARIA LAURA, LICURSI, Valerio, MORCIANO, PATRIZIA, NEGRI, RODOLFO, PORRAZZO, ANTONELLA, Yikang, Rong   +6 more
core   +2 more sources

Phytochemical Analysis of Veratrum Alkaloids in Medicinal Veratrum Globules Using High‐Performance Liquid Chromatography Coupled With Tandem Mass Spectrometry

Biomedical Chromatography, Volume 40, Issue 3, March 2026.
ABSTRACT Veratrum L. species have been used in traditional medicine for centuries due to their bioactive properties, yet they also contain toxic steroid alkaloids that pose potential health risks when present in herbal preparations. Reliable analytical approaches are therefore essential to ensure product safety, protect consumer health and assess ...
Julia Siegle, Jörg Pietsch
wiley   +1 more source

Relevamiento de la producción de lacasa en aislamientos de Colletotrichum (Ascomycota), agente causal de antracnosis de la Soja [PDF]

, 2007
Colletotrichum truncatum es el hongo patógeno más comúnmente asociado con la antracnosis de soja. Aunque la enzima ligninolítica lacasa se relaciona con la patogenicidad de un amplio rango de hongos fitopatógenos, su rol biológico en la interacción ...
Gally, Marcela Edith, Levin, Laura Noemí, Parisi, Matías, Ramos, Araceli Marcela   +3 more
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