Results 51 to 60 of about 17,883 (244)

A Systematic Review of Iran’s Medicinal Plants With Anticancer Effects [PDF]

, 2015
Increase in cases of various cancers has encouraged the researchers to discover novel, more effective drugs from plant sources. This study is a review of medicinal plants in Iran with already investigated anticancer effects on various cell lines.
Asadi-Samani, Majid., Aslani, Elahe., Kooti, Wesam., shirzad, Hedayatollah.   +3 more
core   +1 more source

Vaccarin Improves Myocardial Ischemia–Reperfusion Injury by Attenuating Oxidative Stress and Ferroptosis Through Reducing NOX4‐Modulated JAK2/STAT3 Pathway Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Vaccarin is a naturally occurring flavonoid glycoside with cardioprotective properties; however, its involvement in myocardial ischemia–reperfusion (MI/R) injury remains poorly defined. We herein investigated whether vaccarin protects cardiomyocytes from MI/R‐induced dysfunction in vivo and in vitro and examined the associated molecular ...
Han Yang, Mi Zhou, Feng‐Cai Zhang
wiley   +1 more source

Cucurbitacin E inhibits the Yes‑associated protein signaling pathway and suppresses brain metastasis of human non‑small cell lung cancer in a murine model. [PDF]

, 2019
Human non‑small cell lung cancer (NSCLC) is associated with an extremely poor prognosis especially for the 40% of patients who develop brain metastasis, and few treatment strategies exist.
Hsu, Ping-Chih, Jablons, David M, Liu, Shu, Tian, Bo, Urisman, Anatoly, Wang, Yu-Cheng, Xu, Zhidong, Yang, Cheng-Ta, Yang, Yi-Lin, You, Liang   +9 more
core  

Aphid adaptation to cucurbits: sugars, cucurbitacin and phloem structure in resistant and susceptible melons

BMC Plant Biology, 2023
Background Aphis gossypii, a strictly phloemophagaous aphid, colonize hundreds of plant families, and a group of clones formed a cucurbit-specialised host-race.
Pierre Sadon, Marie-Noëlle Corre, Raphael Lugan, Nathalie Boissot   +3 more
doaj   +1 more source

Cucurbitacin B and cancer intervention: Chemistry, biology and mechanisms (Review)

International Journal of Oncology, 2017
Cancer is one of the most important healthcare matters, with the worst prognosis but the best possibilities for scientific development. It is likely to increase in the future and cause global havoc designating it as an epidemic. Cancer development requires urgent intervention.
Sukant, Garg, Sunil C, Kaul, Renu, Wadhwa   +2 more
openaire   +3 more sources

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

Phytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou, Jingyun Chi, Yuan Ding, Zhidi Zhang, Rui Liang, Tianhao Wang, Yan Jiang, Rujun Song, Huazhou Fu, Xizhen Zhou   +9 more
wiley   +1 more source

Quantification of cucurbitacins B and E in Coccinia grandis fruit ethanolic extract and their anti-inflammatory effects in SARS-CoV-2 protein-stimulated macrophages

Cogent Food & Agriculture
Food-derived bioactive compounds are increasingly being recognized for their potential in modulating inflammatory responses associated with post-infectious health conditions.
Rattanathorn Choonong, Laddawan Senggunprai, Waraporn Putalun, Waranyoo Phoolcharoen   +3 more
doaj   +1 more source

Development of an Artificial Liquid Diet for Allelochemical Delivery in Lycorma delicatula

Journal of Applied Entomology, EarlyView.
ABSTRACT Spotted lanternfly, Lycorma delicatula White (Hemiptera: Fulgoridae), is an invasive phloem‐feeding planthopper native to Asia, which poses a growing threat to US agriculture due to its broad host range and rapid spread since its 2014 detection. To better understand how L.
Brian F. Ruether, Mariana Gelambi, Kate A. Burgiss, Alejandra Caballero, Sherry B. Hildreth, Dorothea Tholl   +5 more
wiley   +1 more source

The cytotoxic Activity of Cucurbitacin E and Busulphan on ovarian and stomach cancer cells in vitro : a comparative study [PDF]

, 1996
A comparative study of the cytotoxicity of cucurbitacin E, a natural product, and busulphan on human ovarian and stomach cell lines was carried out.
Attard, Everaldo, Cuschieri, Alfred, Grixti, Mario, Scicluna-Spiteri, Anthony   +3 more
core  

Targeting tumor-associated macrophages by anti-tumor Chinese materia medica [PDF]

, 2017
Tumor-associated macrophages (TAMs) play a key role in all stages of tumorigenesis and tumor progression. TAMs secrete different kinds of cytokines, chemokines, and enzymes to affect the progression, metastasis, and resistance to therapy depending on ...
A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Saccani, A Schmieder, A Sica, A Sica, B Ruffell, B Shao, BB Aggarwal, BC Kennedy, BK Sekhon, C Jia, C Liu, C Steidl, CE Lewis, CK Mueller, Curzio Rüegg, D Ghosh, DM Mosser, E Bolli, E Schutyser, F Li, F Zhao, FO Martinez, FR Zhao, G Shu, G Solinas, H Diao, H Fritz, H Kurahara, H Kurahara, H Ouyang, H Wang, H Wang, H Zhang, H Zhao, HYT Nguyen, IA Schepetkin, J Cook, J Deng, J Ding, J Gao, J Li, J Li, J Li, J Rius, J Wang, J Yin, J Zhang, JB Mitchem, JW Pollard, JY Jang, JY Shin, Kun Zhou, L Bingle, L Sanchez-Martin, L Varinska, LI Partecke, Li-kang Sun, Lin Miao, M Egeblad, M Hong, M Ito, M Jinushi, M Pesic, MA Khan, Margaret Gebauer, Micheal O. Hottiger, ML Taddei, MR Galdiero, Muriel Cuendet, MY Kim, P Allavena, P Suboj, P Sun, P Yu, PS Kyrn, Q Dong, Q Lin, R Graziose, R Noy, R Ostuni, R Zhu, S Banerjee, S Gao, S Iwanowycz, S Lunardi, S Shi, S Shimura, S Ye, SM Woo, SR Hingorani, SR Hyam, T Kawanishi, T Xu, V Riabov, W Lam, W Shi, Wei-ling Pu, X Jia, X Li, X Lin, X Nie, X Qian, X Sun, X Tang, X Wang, X Zhan, X Zhang, X Zhang, Xiu-mei Gao, XL Zhu, XW Yang, Y Cai, Y Kimura, Y Lei, Y Liu, Y Song, Y Tu, Y Wang, Y Wang, Y Zhao, YP Guo, Yun-sha Zhang, Z Cai, Z Jiang, Z Lin, Z Liu   +131 more
core   +1 more source