Results 31 to 40 of about 17,883 (244)

Enhanced antitumor activity of cucurbitacin B combined with cerulenin in osteosarcoma

open access: yesBangladesh Journal of Pharmacology, 2015
In the present study, the effect of cucurbitacin B and cerulenin combination on osteosarcoma was investigated to develop an effective treatment regimen.
Zhe Zhang, Ying Shen, Jian Wu, Lin Cai
doaj   +1 more source

Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation

open access: yesBMC Complementary and Alternative Medicine, 2012
Background Cucurbitacin B, an oxygenated tetracyclic triterpenoid compound extracted from the Thai medicinal plant Trichosanthes cucumerina L., has been reported to have several biological activities including anti-inflammatory, antimicrobial and ...
Duangmano Suwit   +4 more
doaj   +1 more source

Efficacy of Seed Priming With Cucurbitacin Phytonematicides Against Meloidogyne incognita on Pea

open access: yesFrontiers in Microbiology, 2022
The cost and environment concerns of existing drench-application technologies of cucurbitacin phytonematicides resulted in conceptualization of the priming-and-drying (PAD) technology of seeds with hypogeal germination.
Phatu William Mashela   +2 more
doaj   +1 more source

A Practical Protocol for a Comprehensive Evaluation of Sulfur Fumigation of Trichosanthis Radix Based on Both Non-Targeted and Widely Targeted Metabolomics

open access: yesFrontiers in Plant Science, 2020
Trichosanthis Radix (TR) is one of the most severely sulfur-fumigated herbs in the market, whose transformation mechanism of chemical compositions and sulfur-fumigation markers of TR have not been clarified.
Chuanzhi Kang   +11 more
doaj   +1 more source

Cucurbitacin B 2-Sulfate and Cucurbitacin Glucosides from the Root Bark of Helicteres angustifolia

open access: yesChemical and Pharmaceutical Bulletin, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Zong-Tsi, Chen   +2 more
openaire   +3 more sources

Herbivory reduces plant interactions with above- and belowground antagonists and mutualists. [PDF]

open access: yes, 2012
Herbivores affect plants through direct effects, such as tissue damage, and through indirect effects that alter species interactions. Interactions may be positive or negative, so indirect effects have the potential to enhance or lessen the net impacts of
Adler, L.S.   +4 more
core   +1 more source

Grayanotoxin I Intoxication in Pet Pigs [PDF]

open access: yes, 2018
Contaminated honey is a common cause of grayanotoxin intoxication in humans. Intoxication of animals, especially cattle, is usually due to ingestion of plants of the Ericaceae family, such as Rhododendron. Here, we report the ingestion of Pieris japonica
Köster, Nils   +5 more
core   +1 more source

Metabolic engineering of cucurbitacins in Cucurbita pepo hairy roots

open access: yesFrontiers in Plant Science, 2022
In this paper we show that metabolic engineering in Cucurbita pepo hairy roots can be used to both effectively increase and modify cucurbitacins. Cucurbitacins are highly-oxygenated triterpenoids originally described in the Cucurbitaceae family, but have
Aldo Almeida   +7 more
doaj   +1 more source

Cucurbitacin B Suppresses The Transactivation Activity of RelA/p65

open access: yesThe FASEB Journal, 2011
Cucurbitacin B, a natural triterpenoid is well known for its strong anticancer activity, and recent studies showed that cucurbitacicn B inhibits JAK/STAT3 pathway. In this study, we demonstrate for the first time that cucurbitacin B is also a potent inhibitor of NF‐κB activation. Our results showed that cucurbitacin B inhibited TNF‐α‐induced expression
Hong Ri, Jin   +3 more
openaire   +2 more sources

Cucurbitacin E has neuroprotective properties and autophagic modulating activities on dopaminergic neurons [PDF]

open access: yes, 2014
Natural molecules are under intensive study for their potential as preventive and/or adjuvant therapies for neurodegenerative disorders such as Parkinson’s disease (PD).
Arel-Dubeau, Anne-Marie   +8 more
core   +4 more sources

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