Adaptive Laboratory Evolution of Cupriavidus necator H16 for Carbon Co-Utilization with Glycerol. [PDF]
Int J Mol Sci, 2019 Cupriavidus necator H16 is a non-pathogenic Gram-negative betaproteobacterium that can utilize a broad range of renewable heterotrophic resources to produce chemicals ranging from polyhydroxybutyrate (biopolymer) to alcohols, alkanes, and alkenes. However, C.
González-Villanueva M +6 more
europepmc +7 more sources
Engineering Cupriavidus necator H16 for the autotrophic production of (R)-1,3-butanediol. [PDF]
Metab Eng, 2021 Butanediols are widely used in the synthesis of polymers, specialty chemicals and important chemical intermediates. Optically pure R-form of 1,3-butanediol (1,3-BDO) is required for the synthesis of several industrial compounds and as a key intermediate of β-lactam antibiotic production.
Gascoyne JL +3 more
europepmc +6 more sources
Metabolic Engineering of Cupriavidus necator H16 for Sustainable Biofuels from CO2 [PDF]
Trends in Biotechnology, 2021 Decelerating global warming is one of the predominant challenges of our time and will require conversion of CO2 to usable products and commodity chemicals. Of particular interest is the production of fuels, because the transportation sector is a major source of CO2 emissions. Here, we review recent technological advances in metabolic engineering of the
Justin Panich +2 more
openaire +6 more sources
Improving CO2 assimilation efficiency in Cupriavidus necator H16 [PDF]
, 2021 In this fast-developing world, there is an increasing demand for biodegradable and renewable materials derived from cheap and wildly available resources. Waste gases from industry (steel manufacturing, oil refining, coal and natural/shale gas) can be used as alternatives to petroleum-based solutions.
Tibaldero, Giorgia
core +3 more sources
An Engineered Constitutive Promoter Set with Broad Activity Range for Cupriavidus necator H16 [PDF]
ACS Synthetic Biology, 2018 Well-characterized promoters with variable strength form the foundation of heterologous pathway optimization. It is also a key element that bolsters the success of microbial engineering and facilitates the development of biological tools like biosensors.
Abayomi Oluwanbe Johnson +3 more
openaire +5 more sources
CO2-based production of phytase from highly stable expression plasmids in Cupriavidus necator H16 [PDF]
Microbial Cell FactoriesBackground Existing plasmid systems offer a fundamental foundation for gene expression in Cupriavidus necator; however, their applicability is constrained by the limitations of conjugation.
Simon Arhar +8 more
doaj +2 more sources
Investigating Mass Transfer and Reaction Engineering Characteristics in a Membrane Biofilm Using Cupriavidus necator H16 [PDF]
Membranes, 2023 Membrane biofilm reactors are a growing trend in wastewater treatment whereby gas-transfer membranes provide efficient bubbleless aeration. Recently, there has been a growing interest in using these bioreactors for industrial biotechnology using ...
Burcu Akkoyunlu +3 more
doaj +2 more sources
Metabolic engineering of Cupriavidus necator H16 for sustainable biomanufacturing
, 2023 Uncoupling fuel and chemical production from the consumption of fossil resources is a fundamental challenge for sustainable development. In industrial biomanufacturing, this challenge is most often addressed by using heterotrophic microbes to convert plant biomass into value-added compounds.
Della Valle, Simona
openaire +3 more sources
Strain and model development for auto- and heterotrophic 2,3-butanediol production using Cupriavidus necator H16 [PDF]
Biotechnology for Biofuels and BioproductsThe production of platform chemicals from renewable energy sources is a crucial step towards a post-fossil economy. This study reports on the production of acetoin and 2,3-butanediol heterotrophically with fructose as substrate and autotrophically from ...
Janek R. Weiler +4 more
doaj +2 more sources
Production of succinate with two CO2 fixation reactions from fatty acids in Cupriavidus necator H16 [PDF]
Microbial Cell FactoriesBackground Biotransformation of CO2 into high-value-added carbon-based products is a promising process for reducing greenhouse gas emissions. To realize the green transformation of CO2, we use fatty acids as carbon source to drive CO2 fixation to produce
Linqing Li +4 more
doaj +2 more sources