Results 71 to 80 of about 5,891 (192)
Effect of cuprizone treatment on subcellular morphology. [PDF]
, 2015 Four week-old male mice were treated with cuprizone for one week. Subcellular morphology was assessed in ultrathin thymic sections of control (A) and cuprizone-treated (B-E) mice.
Peter Acs (751324) +10 more
core +1 more source
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
MedComm, Volume 7, Issue 6, June 2026.Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
Brain and BehaviorObjective To investigate whether nicotinamide adenine dinucleotide (NAD+) supplementation can improve behavioral changes in a cuprizone‐intoxicated mouse model.
Shuang Song +6 more
doaj +1 more source
17β-Estradiol Enhances the Efficacy of Adipose-Derived Mesenchymal Stem Cells on Remyelination in Mouse Model of Multiple Sclerosis [PDF]
Acta Medica Iranica, 2012 Previous studies have demonstrated the potential of monotherapy with either mesenchymal stem cells (MSCs) or estrogen in autoimmune and cuprizone models of multiple sclerosis (MS).
Iraj Ragerdi Kashani +7 more
doaj +1 more source
Advanced NanoBiomed Research, Volume 6, Issue 4, April 2026.This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.In an organotypic cerebellar slice culture (OSC) ex vivo demyelination model, teriflunomide has been shown to positively affect myelin preservation during demyelination and enhance remyelination. This is hypothesized as being achieved by modulating the dynamics of glial cells.
Jessica Kronenberg +8 more
wiley +1 more source
An initial top-down proteomic analysis of the standard cuprizone mouse model of multiple sclerosis [PDF]
, 2016 An initial proteomic analysis of the cuprizone mouse model to characterise the breadth of toxicity by assessing cortex, skeletal muscle, spleen and peripheral blood mononuclear cells. Cuprizone treated vs.
Gopinath, Sumana (R17767) +7 more
core +1 more source
Glia, Volume 74, Issue 4, April 2026.Ronzano et al. show that neuronal activity promotes node‐like cluster (NLC) formation before (re)myelination by regulating β1Nav and Nav1.1, which are essential for NLC assembly. This may represent an intermediate step in activity‐driven myelination and contribute to the regulation of axonal conduction.
Rémi Ronzano +10 more
wiley +1 more source
Therapeutic effect of oligomeric proanthocyanidin in cuprizone‐induced demyelination [PDF]
Experimental Physiology, 2019 New Findings What is the central question of this study? Oligomeric proanthocyanidin has the capacity to alleviate abnormalities in neurological functioning. However, whether oligomeric proanthocyanidin can reduce the progression of demyelination or promote remyelination in demyelinating diseases remains unknown.
Qing Wang +10 more
openaire +2 more sources
Effect of cuprizone treatment on thymocytes. [PDF]
, 2015 Four week-old male mice were treated with cuprizone for one week, then immune-staining (A) with FITC-labelled anti-CD4 (green) and Alexa647-labelled anti-CD8 (red) antibodies was performed on thymic sections of untreated (Control) and cuprizone-treated ...
Peter Acs (751324) +10 more
core +1 more source