Results 81 to 90 of about 8,969 (212)
Sex Differences in Metabolite–Immune Circuits of Neuroinflammation
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Sex is a fundamental yet underexplored determinant of human neuroinflammation. Across autoimmune, neurodegenerative, and post‐infectious neurological syndromes, males and females exhibit consistent differences in disease vulnerability, progression, and immune tone.
Priyanka Saminathan +6 more
wiley +1 more source
IκB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-κB in the central nervous system [PDF]
, 2017 The IκB kinase complex induces nuclear factor kappa B activation and has recently been recognized as a key player of autoimmunity in the central nervous system.
Bethea, John R. +16 more
core
The relationships between vitamin K and cognition: a review of current evidence [PDF]
, 2019 Vitamin K is a fat-soluble nutrient discovered in 1935 and its role in blood coagulation has been thoroughly explored. In recent years, studies conducted in vitro and on animals highlighted vitamin K involvement in brain cells development and survival ...
Alisi, Ludovico +7 more
core +2 more sources
European Journal of Immunology, Volume 56, Issue 2, February 2026.Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley +1 more source
Photometric detection in flow analysis systems using integrated PEDDs [PDF]
, 2005 A novel inexpensive optical-sensing technique has been developed for colorimetric flow analysis. This sensing system employs two LEDs whereby one is used as the light source and the other as a light detector.
Diamond, Dermot +2 more
core +2 more sources
Oligodendrocyte: Development, Plasticity, Biological Functions, Diseases, and Therapeutic Targets
MedComm, Volume 7, Issue 2, February 2026.The oligodendrocyte lineage and its roles in development, plasticity, and CNS homeostasis have been shown to have the potential to treat neurological diseases. However, the main obstacles to clinical translation, particularly in terms of BBB challenges and precise delivery.
Qiong Xiang +6 more
wiley +1 more source
Cells, 2019 Brain volume measurement is one of the most frequently used biomarkers to establish neuroprotective effects during pre-clinical multiple sclerosis (MS) studies.
Tanja Hochstrasser +9 more
doaj +1 more source
The Journal of Physiology, Volume 604, Issue 4, Page 1558-1574, 15 February 2026.Abstract figure legend The glia‐immune network involves the communication(s) of glia via immune signalling pathways. In neuro‐homeostasis these pathways have been shown to modulate key processes such as synaptic pruning and myelination. The dynamics of these processes is critical to CNS function.
Verity F. T. Mitchener +2 more
wiley +1 more source
Delayed Demyelination and Impaired Remyelination in Aged Mice in the Cuprizone Model
Cells, 2020 To unravel the failure of remyelination in multiple sclerosis (MS) and to test promising remyelinating treatments, suitable animal models like the well-established cuprizone model are required. However, this model is only standardized in young mice. This
Stefan Gingele +7 more
doaj +1 more source
CXCL10 Triggers Early Microglial Activation in the Cuprizone Model [PDF]
The Journal of Immunology, 2015 Abstract A broad spectrum of diseases is characterized by myelin abnormalities and/or oligodendrocyte pathology. In most, if not all, of these diseases, early activation of microglia occurs. Our knowledge regarding the factors triggering early microglia activation is, however, incomplete.
Clarner, T. +16 more
openaire +3 more sources