Results 131 to 140 of about 7,425 (214)

Pharmacologically Targeting Ferroptosis and Cuproptosis in Neuroblastoma

Molecular Neurobiology
Neuroblastoma is a deadly pediatric cancer that originates from the neural crest and frequently develops in the abdomen or adrenal gland. Although multiple approaches, including chemotherapy, radiotherapy, targeted therapy, and immunotherapy, are recommended for treating neuroblastoma, the tumor will eventually develop resistance, leading to treatment ...
Liu, Ying, Fleishman, Joshua S., Wang, Hongquan, Huo, Liang   +3 more
openaire   +2 more sources

Identification and validation of potential diagnostic signature and immune cell infiltration for HIRI based on cuproptosis-related genes through bioinformatics analysis and machine learning [PDF]

Background and aimsCuproptosis has emerged as a significant contributor in the progression of various diseases. This study aimed to assess the potential impact of cuproptosis-related genes (CRGs) on the development of hepatic ischemia and reperfusion ...
Fang Xiao, Fang Xiao, Fang Xiao, Guandou Yuan, Guandou Yuan, Guandou Yuan, Guoqing Ouyang, Guoqing Ouyang, Guoqing Ouyang, Guozhen Huang, Guozhen Huang, Guozhen Huang, Shuangjiang Li, Shuangjiang Li, Shuangjiang Li, Songqing He, Songqing He, Songqing He, Stephen Tomlinson, Yong Wang, Yong Wang, Yong Wang, Yonglian Zeng, Yonglian Zeng, Yonglian Zeng, Zhi Tan, Zhi Tan, Zhi Tan, Zhipeng Liu, Zhipeng Liu, Zhipeng Liu   +30 more
core   +1 more source

Regulating copper homeostasis of tumor cells to promote cuproptosis for enhancing breast cancer immunotherapy

Nature Communications
Cuproptosis is an emerging mode of programmed cell death for tumor suppression but sometimes gets resisted by tumor cells resist under specific mechanisms.
Meng Guan, Kai Cheng, Xiao-Ting Xie, Yong Li, Meng-Wen Ma, Bin Zhang, Si Chen, Wei Chen, Bo Liu, Jin-Xuan Fan, Yuan-Di Zhao   +10 more
doaj   +1 more source

Cuproptosis-related genes and agents: implications in tumor drug resistance and future perspectives [PDF]

In the field of tumor treatment, drug resistance remains a significant challenge requiring urgent intervention. Recent developments in cell death research have highlighted cuproptosis, a mechanism of cell death induced by copper, as a promising avenue ...
Bin Zhang, Bin Zhang, Daizhou Zhang, Daizhou Zhang, Lingwen Xu, Lingwen Xu, Wenjie Ren, Wenjie Ren, Wentao Liu, Wentao Liu, Xiangyu Kong, Xiangyu Kong, Xiaolan Cao, Xinzhi Li, Xinzhi Li, Xuan Tang, Xuan Tang, Yuxiao Deng, Yuxiao Deng   +18 more
core   +1 more source

Identification of cuproptosis-related genes in Alzheimer’s disease based on bioinformatic analysis

European Journal of Medical Research
Objective To explore the role of cuproptosis in Alzheimer’s disease (AD). Methods An AD-related microarray dataset was downloaded from the Gene Expression Omnibus (GEO) database (GSE140830).
Ming-ming Ma, Jing Zhao, Ling Liu, Cai-ying Wu   +3 more
doaj   +1 more source

Molecular function validation and prognostic value analysis of the cuproptosis-related gene ferredoxin 1 in papillary thyroid carcinoma

Scientific Reports
Cuproptosis, a copper-dependent distinct form of cell death, holds a critical role in tumor development. However, further investigation is needed to elucidate the impact of the cuproptosis signaling on thyroid cancer.
Shiyue He, Wenzhong Peng, Xinyue Hu, Yong Chen   +3 more
doaj   +1 more source

Issue Information

Experimental Physiology, Volume 111, Issue 2, Page 580-585, 1 February 2026.
wiley   +1 more source

Advancing precision oncology:Molecular insights and personalized therapeutic strategies in gastrointestinal cancers [PDF]

Gastrointestinal (GI) cancers, including esophageal adenocarcinoma, pancreatic ductal adenocarcinoma, and colorectal cancer, are among the most common and challenging cancers.
Dings, M.P.G.
core  

Wilson Disease: Why Early Diagnosis Matters and How to Improve Screening

Wilson disease is a genetic disorder of copper metabolism caused by mutations in the ATP7B gene, leading to copper accumulation in the liver, brain, and other organs.
Charzewski, Piotr, Starzyk, Agnieszka
core   +1 more source

Exploring Cuproptosis-Related Genes and Diagnostic Models in Renal Ischemia-Reperfusion Injury Using Bioinformatics, Machine Learning, and Experimental Validation [PDF]

Changhong Xu,1,* Yun Deng,1,* Xinyi Gong,2,* Huabin Wang,1 Jiangwei Man,1 Hailong Wang,1 Kun Cheng,1 Huiming Gui,1 Shengjun Fu,1 Shenghu Wei,3 Xiaoling Zheng,4 Tuanjie Che,4 Liyun Ding,3 Li Yang1 1Department of Urology, Institute of Urology ...
Che T, Cheng K, Deng Y, Ding L, Fu S, Gong X, Gui H, Man J, Wang H, Wang H, Wei S, Xu C, Yang L, Zheng X   +13 more
core   +1 more source