Results 71 to 80 of about 21,433 (201)
Influence of Acupuncture on the Immune Function of Immunosuppressive Cx43 Knockout Mice
针刺研究, 2007 Objective: To observe the influence of acupuncture on the immune function in immunosuppressive Cx43 knockout mice so as to explore the relationship between connexin 43(Cx43) and acupuncture signal transmission.Methods: Eighteen male Cx43 knockout mice ...
WU Xiao-hua +3 more
doaj +2 more sources
Effect of Cx43 downregulation on hESC stemness.
, 2013 Downregulation of Cx43 and stemness gene (OCT4, SOX2, and NANOG) expression in Cx43-siRNA-treated hESCs was confirmed by qRT-PCR after 2 days culture (A) and Western blot analysis after 4 days culture (B). The percentage of AP-positive colonies formed by
Dong Ryul Lee (141574) +9 more
core +1 more source
Andrology, EarlyView.ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus +6 more
wiley +1 more source
Expression of Cx43 in hESCs and hASCs.
, 2013 The expression of endogenous Cx43 in hESCs and hASCs was confirmed by qRT-PCR (A) and Western blot analysis (B). Expression of OCT4 (red) and Cx43 (green) in hESCs and hASCs was observed by immunocytochemistry (C).
Dong Ryul Lee (141574) +9 more
core +1 more source
Targeting CKIP‐1 for Disease Therapy: Cellular Functions, Molecular Networks, and Clinical Potential
Cell Proliferation, EarlyView.CKIP‐1, as a scaffold protein with special structural domains, treats related diseases through multiple emerging targeted technologies.
Xin Huang +4 more
wiley +1 more source
Bone ResearchCraniometaphyseal dysplasia (CMD), a rare craniotubular disorder, occurs in an autosomal dominant (AD) or autosomal recessive (AR) form. CMD is characterized by hyperostosis of craniofacial bones and metaphyseal flaring of long bones.
Yasuyuki Fujii +9 more
doaj +1 more source
Confirmation of Cx43 deletion by X-gal staining.
, 2013 The figure shows X-gal staining of osteoblasts isolated from femurs and tibia of a wild type (Cx43flx/flx, WT) and a Cx43 deficient (OC-Cre;Cx43flx/flx, KO) mouse. Cells from wild type mice had no blue staining indicating that floxed Cx43 was not deleted
Vikram Sathyendra (345239) +8 more
core +1 more source
The FEBS Journal, EarlyView.Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi +12 more
wiley +1 more source
Chronic thrombin treatment increases Cx43 protein expression.
, 2014 HPAECs were left untreated or treated hourly with thrombin (0.5 U/mL) over 6 hr. and Cx43 protein and mRNA were measured. A.) Representative immunoblot shows Cx43 protein levels in thrombin (thr) or control (C) HPAECs.
Anna A. Birukova (333901) +3 more
core +1 more source
The FEBS Journal, EarlyView.Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester +11 more
wiley +1 more source