Comprehensive analysis of prognostic value and immune infiltration of CXC chemokines in pancreatic cancer [PDF]
BMC Medical Genomics, 2022 Background The prognosis of pancreatic cancer is poor, with a 5-year survival rate of less than 10%. Studies have shown that chemokines in the tumour microenvironment are often altered, which is associated with immune infiltration and the prognosis and ...
Yanhua Jing +3 more
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Prognostic Biomarkers and Immunotherapeutic Targets Among CXC Chemokines in Pancreatic Adenocarcinoma [PDF]
Frontiers in Oncology, 2021 BackgroundPancreatic cancer is one of the principal causes of tumor-related death worldwide. CXC chemokines, a subfamily of functional chemotactic peptides, affect the initiation of tumor cells and clinical outcomes in several human malignant tumors ...
Jiacheng Huang +9 more
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Analysis of therapeutic targets and prognostic biomarkers of CXC chemokines in cervical cancer microenvironment [PDF]
Cancer Cell International, 2021 Background The tumor microenvironment (TME) has received an increasing amount of attention. CXC chemokines can regulate immune cell transport and tumor cell activity to exert anti-tumor immunity.
Weina Kong +7 more
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Prognostic Significance and Therapeutic Target of CXC Chemokines in the Microenvironment of Lung Adenocarcinoma [PDF]
International Journal of General Medicine, 2022 Kun Wang, Rongyang Li, Yu Zhang, Weifeng Qi, Tao Fang, Weiming Yue, Hui Tian Department of Thoracic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, People’s Republic of ChinaCorrespondence: Hui Tian ...
Wang K +6 more
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CXC Chemokines in the Pathogenesis of Pulmonary Disease and Pharmacological Relevance [PDF]
International Journal of Inflammation, 2022 Chemokines and their receptors play important roles in the pathophysiology of many diseases by regulating the cellular migration of major inflammatory and immune players.
Kayode Komolafe, Maricica Pacurari
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CXC Chemokines as Therapeutic Targets and Prognostic Biomarkers in Skin Cutaneous Melanoma Microenvironment [PDF]
Frontiers in Oncology, 2021 BackgroundSkin Cutaneous Melanoma (SKCM) is a tumor of the epidermal melanocytes induced by gene activation or mutation. It is the result of the interaction between genetic, constitutional, and environmental factors.
Xuezhi Zhou +7 more
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The Role of CXC Chemokines in Cardiovascular Diseases [PDF]
Frontiers in Pharmacology, 2022 Cardiovascular disease (CVD) is a class of diseases with high disability and mortality rates. In the elderly population, the incidence of cardiovascular disease is increasing annually.
Xiyi Lu +12 more
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The role of proinflammatory cytokines and CXC chemokines (CXCL1–CXCL16) in the progression of prostate cancer: insights on their therapeutic management [PDF]
Cellular & Molecular Biology LettersReproductive cancers are malignancies that develop in the reproductive organs. One of the leading cancers affecting the male reproductive system on a global scale is prostate cancer (PCa). The negative consequences of PCa metastases endure and are severe,
Amin Ullah, Wang Jiao, Bairong Shen
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Identification of Therapeutic Targets and Prognostic Biomarkers Among CXC Chemokines in the Renal Cell Carcinoma Microenvironment [PDF]
Frontiers in Oncology, 2020 Background: Renal cell carcinoma (RCC) is one of the most common malignances with an ever-increasing incidence and high mortality. Cross-talk between cancer cells and interstitial cells exerts significant effects on neoplasia and tumor development and is
Qingquan Zeng +5 more
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CC and CXC chemokines play key roles in the development of polyomaviruses related pathological conditions [PDF]
Virology Journal, 2021 It has been reported that polyomaviruses are the microbes which can be a cause of several human pathological conditions including cancers, nephropathy, progressive multifocal leukoencephalopathy and gynaecological disease. Although investigators proposed
Mohammad Hassan Mohammadi +1 more
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