The Role of CXC Chemokines in Cancer Progression. [PDF]
Cancers (Basel), 2022 CXC chemokines are small chemotactic and secreted cytokines. Studies have shown that CXC chemokines are dysregulated in multiple types of cancer and are closely correlated with tumor progression. The CXC chemokine family has a dual function in tumor development, either tumor-promoting or tumor-suppressive depending on the context of cellular signaling.
Wu T, Yang W, Sun A, Wei Z, Lin Q.
europepmc +5 more sources
The role of CXC chemokines and receptors in breast cancer [PDF]
Clinical and Experimental MedicineCXC chemokines are a class of cytokines possessing chemotactic properties. Studies indicate that CXC chemokines exhibit dysregulation in miscellaneous cancer categories and are significantly associated with the advancement of tumors. Breast cancer is a commonly diagnosed and fatal cancer among the female population.
Mahdi Masrour +2 more
exaly +4 more sources
A comprehensive bioinformatics analysis to identify potential prognostic biomarkers among CC and CXC chemokines in breast cancer [PDF]
Scientific Reports, 2022 Breast cancer (BC) is a major human health problem due to its increasing incidence and mortality rate. CC and CXC chemokines are associated with tumorigenesis and the progression of many cancers.
Hossein Hozhabri +3 more
doaj +2 more sources
Screening of CXC chemokines in the microenvironment of ovarian cancer and the biological function of CXCL10 [PDF]
World Journal of Surgical Oncology, 2021 Background This study aims to screen and identify the biological functions and prognostic value of CXC chemokines in ovarian cancer (OC) through bioinformatics and molecular biology methods, and to provide data support for the selection of biomarkers and
Weiyuan Li +3 more
doaj +2 more sources
Vaccines, 2022 COVID-19 is one of the progressive viral pandemics that originated from East Asia. COVID-19 or SARS-CoV-2 has been shown to be associated with a chain of physio-pathological mechanisms that are basically immunological in nature.
Mojgan Noroozi Karimabad +1 more
exaly +3 more sources
Regulation of Expression of CXC Chemokines in Cultured Hepatocytes [PDF]
Iranian Journal of Public Health, 2005 Chemokines are low molecular weight proteins (8-17 kDa). They are classified in four distinct groups as CXC, CC, CX3C and C. Depending on the presence or absence of a motif called ELR (Arg-Leu-Glu) before the first cysteine residue in their structure ...
GhH Hassanshahiraviz, AJ Dickson
doaj +4 more sources
Molecular Identification and Dual Functions of Two Different CXC Chemokines in Nile Tilapia (Oreochromis niloticus) against Streptococcus agalactiae and Flavobacterium columnare [PDF]
Microorganisms, 2020 Two CXC chemokines in Nile tilapia (On-CXC1 and On-CXC2) were identified at both the genomic and proteomic levels. A southern blot analysis and comparison searching in Ensembl confirmed the typical structure of the CXC chemokine genes and provided ...
Chatsirin Nakharuthai +1 more
doaj +2 more sources
Epigenetics underpinning the regulation of the CXC (ELR+) chemokines in non-small cell lung cancer. [PDF]
PLoS ONE, 2011 BACKGROUND:Angiogenesis may play a role in the pathogenesis of Non-Small Cell Lung cancer (NSCLC). The CXC (ELR(+)) chemokine family are powerful promoters of the angiogenic response.
Anne-Marie Baird +2 more
doaj +3 more sources
The expression and role of CXC chemokines in colorectal cancer [PDF]
Cytokine & Growth Factor Reviews, 2011 Cancer is a life-threatening disease world-wide and colorectal cancer is the second common cause of cancer mortality. The interaction between tumor cells and stromal cells plays a crucial role in tumor initiation and progression and is partially mediated by chemokines.
Hannelien, Verbeke +3 more
openaire +3 more sources
A narrative review: CXC chemokines influence immune surveillance in obesity and obesity-related diseases: Type 2 diabetes and nonalcoholic fatty liver disease [PDF]
Reviews in Endocrine and Metabolic Disorders, 2023 Amin Ullah, Ahmad Ud Din, Wen Ding
exaly +2 more sources