Results 121 to 130 of about 44,475 (230)

Integrated Single‐Cell RNA Sequencing and Untargeted Metabolomics Reveals β‐Elemene's Immune and Metabolic Modulation in Triple‐Negative Breast Cancer

MedComm – Oncology, Volume 5, Issue 3, September 2026.
In a 4T1 TNBC model, β‐elemene suppressed tumor growth and pulmonary metastasis. scRNA‐seq showed it remodeled the tumor microenvironment by reducing cancer‐associated fibroblasts, enhancing antigen presentation, and inhibiting pro‐tumorigenic ECM remodeling. Metabolomics revealed prostaglandin downregulation.
Zhiqiang Luo, Guohua Yu, Huixia Fan, Ruofan Guo, Jingqi Zheng, Chen Wang, Ruyi Jin, Junhui Zhou, Jian Yang   +8 more
wiley   +1 more source

CXCL12 levels correlate with reduced stroke severity and lower risk of hemorrhagic transformation in stroke patients. [PDF]

Front Cardiovasc Med
Ostos F, Moraga A, Cuartero MI, Vázquez-Reyes S, Peña-Martínez C, Seoane D, Gutiérrez-Sánchez M, Martínez-Salio A, Diaz-Benito B, Calleja P, García-Culebras A, Moro MÁ, Lizasoain I.   +12 more
europepmc   +1 more source

Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal, Anuradha Bankar, Vinicio A. de Jesus Perez   +2 more
wiley   +1 more source

IL-1β/CXCL12 signalling orchestrates adipocyte-pancreatic neuroendocrine tumor crosstalk. [PDF]

J Transl Med
Oldani M, Grassi ES, Gaudenzi G, Rybinska I, Carra S, Massardi E, Fazio N, Caraglia M, Persani L, Vitale G.   +9 more
europepmc   +1 more source

Circulating Tumor Cells in Multiple Myeloma: From Peripheral Clues to Central Insights

American Journal of Hematology, Volume 101, Issue 7, Page 1575-1588, July 2026.
CTC offer a minimally invasive widow into systemic myeloma biology, overcoming the sampling bias of bone marrow biopsies. Their prognostic value at diagnosis, potential role in MRD monitoring, and ability to capture clonal evolution highlight them as actionable biomarkers for future precision medicine.
Benjamin Podvin, Bruno Paiva, Irene M. Ghobrial, Salomon Manier   +3 more
wiley   +1 more source

Integrative Transcriptomic Analysis Identifies CXCL12 as a Candidate Hub Gene Associated with CD4⁺ T-Cell Immune Network Remodeling in Secondary Lymphedema. [PDF]

J Inflamm Res
Huang X, Lu C, Tan Z, Xu J.
europepmc   +1 more source

Deciphering the Therapeutic and Preventive Potential of Dietary Tannins in Osteosarcoma: A Multi‐Omics Approach Targeting TGFA and Immune Microenvironment Remodeling

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Dietary tannin‐associated molecular programs converge on a TGFA‐centered regulatory axis that governs osteosarcoma progression and immune remodeling. Multi‐omics integration combined with machine learning identifies a tannin‐related risk score (TRR) that stratifies tumor aggressiveness and immune landscape heterogeneity.
Ge Yunling, Xu Jietao, Xiao He, Zhao Tingxiao, Lv Jun, Zhou Hong, Qian Jiawei, Wang Xijun, Kang Yao   +8 more
wiley   +1 more source

CXCL12 wt Allele [PDF]

, 2020
openaire   +1 more source

<i>CXCL12</i> rs1801157 Polymorphism Is Associated with Antiatherogenic Lipoprotein Subfraction Profile Independent of Coronary Artery Disease Risk in a Turkish Population: A Case-Control Study. [PDF]

J Clin Med
Deniz İ, Türer Cabbar A, Akdeniz FT, İsbir T, Güleç Yılmaz S.   +4 more
europepmc   +1 more source

Multi-omics reveals a novel Cxcr4⁺ subpopulation of alveolar macrophages and therapeutic effect of AMD3100 in mice with advanced silicosis. [PDF]

Clin Transl Med
Mu M, Li B, Cao H, Zou Y, Yan R, Wang F, Zhao Y, Xie Z, Du M, Wu X, Tao X, Wang J.   +11 more
europepmc   +1 more source