Results 141 to 150 of about 44,475 (230)

The Complex Relation of Branched‐Chain Amino Acids and Inflammation in the Obesity and Diabetes Context

Obesity Reviews, Volume 27, Issue 7, July 2026.
ABSTRACT In a scenario with increasing cases of obesity and diabetes worldwide, branched‐chain amino acids (BCAA) metabolism has become an important factor in the understanding of these pathologies. More recently, its chronic high plasma levels have been postulated, alongside glucose, inflammatory factors, and other molecules, as an important ...
Bernardo Starling‐Soares, Monique Macedo Coelho, Bruna Guerra Campolina, Camila Kümmel Duarte, Tatiani Uceli Maioli   +4 more
wiley   +1 more source

Longitudinal localization of leukaemic stem cells between the metaphysis and central marrow governs their behaviour. [PDF]

Nat Cell Biol
Wang C, Pan Y, Dong R, Zhou W, Meng X, Kang X, Nistala R, Hammer RD, Li L, Kang X.   +9 more
europepmc   +1 more source

Disease‐Associated Remodeling of m6A RNA Methylation in Human Interstitial Cells From Fibro‐Calcific Aortic Valves

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Direct RNA sequencing of primary human valvular interstitial cells (VICs) from non‐calcified control and fibro‐calcific aortic stenosis (AS) valves reveals disease‐associated remodeling of m6A RNA methylation. AS‐derived VICs show an overall increase in detected m6A sites, together with transcript‐specific hyper‐ and hypo‐methylation patterns ...
Vincenza Valerio, Omar Molla, Ilaria Massaiu, Gloria Garoffolo, Veronika A. Myasoedova, Mattia Chiesa, Paolo Poggio   +6 more
wiley   +1 more source

hucMSCs alleviate LPS-induced endothelial glycocalyx damage by secreting Cxcl12 to activate CXCR4. [PDF]

Stem Cell Res Ther
Cui J, Peng Z, Chen Y, Liu W, Chen Q, Wang X, Wang T, Huang X, Sun T.   +8 more
europepmc   +1 more source

Integrating gene-microbiome interactions and single-cell transcriptomics reveals therapeutic strategies for aortic aneurysm. [PDF]

iScience
Liu J, Han W, Wang D, Aierken Y, Liu Z, Wang J, Guo J, Li Y, Dai X.   +8 more
europepmc   +1 more source

CXCL12-mediated T cell infiltration drives breast cancer metastasis. [PDF]

Clin Exp Med
Liu X, Chen C, Liu L, Tang J, Zhang H, Jin G, Chen Y.   +6 more
europepmc   +1 more source

Genome‐wide association study in 21,271 individuals identifies 9 novel loci associated with circulating CD34+ hematopoietic stem and progenitor cell levels

HemaSphere, Volume 10, Issue 7, July 2026.
Yuwen Xie, Antton Lamarca, Caterina Cafaro, Gudmar Thorleifsson, Ludvig Ekdahl, Daniela Torres Di Bello, Zain Ali, Yen La, Lilja Stefansdottir, Alex Antill, Maroulio Pertesi, Maria Laura Mahecha Escobar, Magnús K. Magnússon, Simon N. Stacey, Kari Stefansson, Ingileif Jonsdottir, Göran Karlsson, Thorunn Olafsdottir, Unnur Thorsteinsdottir, Aitzkoa Lopez de Lapuente Portilla, Björn Nilsson   +20 more
wiley   +1 more source

A CXCR4 targeting peptide delivered by silica nanoparticles eliminates migrating cancer stem cells in pancreatic ductal adenocarcinoma. [PDF]

Sci Rep
Tiwary K, Lahusen A, Inaas S, Beitzinger B, Schmid R, Harms M, Hauff S, Arnold F, Walter K, Alcala S, Hahn S, Heßmann E, Kleger A, Azoitei N, Seufferlein T, Sainz B, Münch J, Lindén M, Hermann PC.   +18 more
europepmc   +1 more source

Substrate stiffness modulates human gingival fibroblast paracrine signaling to promote osteogenic differentiation of human periodontal ligament cells. [PDF]

Front Bioeng Biotechnol
Tiskratok W, Yamada M, Kyawsoewin M, Lwin HY, Egusa H, Jitprasertwong P, Limraksasin P.   +6 more
europepmc   +1 more source

The potential directing role of chemokines for specific metastatic sites in breast cancer. [PDF]

Sci Rep
Ayoub AM, El-Houseini ME, Tharwat E, Bayomy MFF, Abdellateif MS.   +4 more
europepmc   +1 more source