Results 131 to 140 of about 44,475 (230)

Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu, Usri H. Ibrahim, Irene Mackraj, Carola Niesler   +3 more
wiley   +1 more source

The CXCL12-CXCR4 axis in colorectal cancer: immune regulation, metastatic progression, and therapeutic implications. [PDF]

Front Immunol
Tian S, Liu J, Yang X, Guo J.
europepmc   +1 more source

EGFR‐Targeting IgG1 Antibody Enhances NK Cell‐Mediated Tumor Killing in KRAS‐Mutant Pancreatic Cancer

MedComm, Volume 7, Issue 7, July 2026.
In KRAS‐mutant pancreatic cancer, persistent downstream signaling can limit the efficacy of EGFR‐targeting mAbs. However, the addition of NK cells enables nimotuzumab to effectively direct a potent antitumor response via antibody‐dependent cellular cytotoxicity (ADCC), overcoming this resistance mechanism.
Ruoxi Xiao, Xiaoxiao Li, Ping Li, Junjin Wang, Xiaoyuan Sun, Chenyang Zhao, Zimin Liu, Ruining Gong, Minghan Ren, Ke Lei, He Ren   +10 more
wiley   +1 more source

Placode-derived orphan chemokine CXCL14 is critical for proper chick trigeminal ganglion formation. [PDF]

Dev Biol
Urrutia HA, Gao J, Bronner ME.
europepmc   +1 more source

Secondary Analysis of the CAN‐Study, a Randomised Controlled Trial – Local Anaesthesia and Overall Survival

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Introduction This study investigates long‐term survival in the Cancer and Anaesthesia (CAN) study, focusing on the potential impact of local anaesthetic infiltration during breast cancer surgery. A positive effect from peritumoral infiltration has recently been suggested.
Mats Enlund, Anders Berglund, Leif Bergkvist, on behalf of the CAN‐Study‐Group, Rebecca Ahlstrand, Andreas Ekman, Anna Enlund, Per Flisberg, Lars Hedlund, Johan Lundberg, Dong‐Xin Wang, Fredrik Wärnberg, Ingrid Östlund   +12 more
wiley   +1 more source

Senolytic Treatment With Fisetin Reverses Age-Related Endothelial Dysfunction Partially Mediated by SASP Factor CXCL12. [PDF]

Aging Cell
Mahoney SA, Mazan-Mamczarz K, Tsitsipatis D, VanDongen NS, Henry-Smith C, Okereke AN, Munk R, Darvish S, Murray KO, De S, Gorospe M, Seals DR, Rossman MJ, Herman AB, Clayton ZS.   +14 more
europepmc   +1 more source

Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer

Immunology, Volume 178, Issue 3, Page 377-386, July 2026.
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros, Gabriel Augusto Leite, Arthur Gomes de Andrade, Maria Danielma dos Santos Reis, Luiz Henrique Agra Cavalcante‐Silva, Marvin Paulo Lins   +5 more
wiley   +1 more source

Pharmacological modulation of CXCL12/CXCR4/ACKR3 for brain disorders - an overview. [PDF]

Cell Commun Signal
Kuppens A, Rogister B, Neirinckx V.
europepmc   +1 more source

Ovarian hormones and high‐fat diet duration distinctively modulate hypothalamic chemokine profile

Journal of Neuroendocrinology, Volume 38, Issue 7, July 2026.
Abstract Excessive intake of saturated fats triggers inflammation in the hypothalamus, a key regulator of energy balance. In the chronic phase of this inflammatory response, bone marrow‐derived and lymphoid cells are chemoattracted to this region, partially mitigating high‐fat diet (HFD)‐induced metabolic impairments.
Alexia Guimaraes Batista Augusto, Giovanna Ariozi dos Santos, Igor Vinicius Sousa Cavalheiro, Vinicius Stefanini Mantovan, Larissa Silva Bergantini, Nicolly Porto Marin, Ester dos Santos Alves, Licio Augusto Velloso, Natalia Ferreira Mendes   +8 more
wiley   +1 more source

Insights into the context-dependent immunological roles of the CXCL12-CXCR4 axis in alopecia. [PDF]

Front Immunol
Sung JH, Zheng M, Park IG, An S, Cho J, Noh M.   +5 more
europepmc   +1 more source