Results 151 to 160 of about 142,759 (329)
PGK1 contributes to tumorigenesis and sorafenib resistance of renal clear cell carcinoma via activating CXCR4/ERK signaling pathway and accelerating glycolysis [PDF]
, 2022 Yu He +10 more
openalex +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Triple‐negative breast cancer (TNBC) is characterized as an aggressive malignancy with limited therapeutic options. The circular RNA circ_0006174 has been implicated in oncogenic processes across various cancers; however, its specific role in the pathogenesis of TNBC remains unclear.
Yong‐Zhe Tang +4 more
wiley +1 more source
Significance of CXCL12/CXCR4 Ligand/Receptor Axis in Various Aspects of Acute Myeloid Leukemia
Cancer Management and Research, 2020 Zinat Yazdani,1 Zahra Mousavi,2 Alireza Moradabadi,1 Gholamhossein Hassanshahi1,3 1Department of Hematology and Blood Banking, Kerman University of Medical Sciences, Kerman, Iran; 2Department of Hematology and Medical Laboratory Sciences, Iranshahr ...
Yazdani Z +3 more
doaj
Role of CXCR4 as a Prognostic Biomarker Associated With the Tumor Immune Microenvironment in Gastric Cancer [PDF]
, 2021 Yuyang Gu +5 more
openalex +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu +5 more
wiley +1 more source
Med Research, EarlyView.Intra‐tumour heterogeneity is present in gastrointestinal tumours at the single‐cell level. Cell cycling, EMT, MYC and TNF‐α are the four main consensus meta‐programs in gastrointestinal tumours. Then, a prognostic model based on intratumoral heterogeneity was constructed using an artificial intelligence‐derived prognostic index.
Zhizhan Ni +12 more
wiley +1 more source
Med Research, EarlyView.ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang +22 more
wiley +1 more source
Medicinal Research Reviews, EarlyView.ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi +6 more
wiley +1 more source
Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development. [PDF]
Adv Sci (Weinh)Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Tong J +21 more
europepmc +2 more sources