Results 211 to 220 of about 142,759 (329)

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Dual blockade of DPP-4 and CXCL12/CXCR4 axes synergistically protects podocytes in lupus nephritis. [PDF]

Front Pharmacol
Hu HM, Li YC, Zhang YM, Zhu TY, Yong WJ, Gan YH, Liu C, Duan RY, Xu HD, Zhao ZZ, Qi YY.   +10 more
europepmc   +1 more source

Development of a Novel SPR Assay to Study CXCR4–Ligand Interactions [PDF]

, 2020
Arnaud Boonen, Abhimanyu K. Singh, Anneleen Van Hout, Kalyan Das, Tom Van Loy, Sam Noppen, Dominique Schols   +6 more
openalex   +1 more source

Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies

Psychiatry and Clinical Neurosciences, EarlyView.
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda, Michihiro Toritsuka, Hiroto Tamakoshi, Nakao Iwata, Manabu Makinodan   +4 more
wiley   +1 more source

CXCR4 wt Allele [PDF]

, 2020
openaire   +1 more source

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source

Driver mutation-defined molecular landscapes of essential thrombocythemia. [PDF]

Blood Sci
Lorenzen AL, Huang G.
europepmc   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Inhibition of CXCR4 suppresses bone invasion in a murine model of oral squamous cell carcinoma. [PDF]

BMC Oral Health
Liu L, Huang Y, Zhang Q, Zheng K, Yan G.
europepmc   +1 more source

Progress Toward Rationally Designed Small-Molecule Peptide and Peptidomimetic CXCR4 Antagonists

, 2015
Jon Våben⊘, Bengt Erik Haug, Mette M. Rosenkilde   +2 more
openalex   +2 more sources