Results 211 to 220 of about 157,119 (339)

Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs, Eslam A. Elghonaimy, Praveen Ramakrishnan Geethakumari, Kiran A. Kumar, Joseph F. Merola, Heather W. Goff, Todd A. Aguilera   +6 more
wiley   +1 more source

Identification of hypoxia-related gene signatures and molecular subtypes in chronic rhinosinusitis with nasal polyps. [PDF]

Braz J Otorhinolaryngol
Song L, Zhou S, Wang L, Lai J, Tan S, Yao C, Yu S.   +6 more
europepmc   +1 more source

CXCR4 involvement in neurodegenerative diseases [PDF]

, 2018
Karch, Celeste M., Wen, Natalie
core   +1 more source

Prognostic Significance of the Pretreatment Neutrophil‐to‐Lymphocyte Ratio and Tumor‐Associated Neutrophils in Head and Neck Squamous Cell Carcinoma: Systematic Review and Meta‐Analysis

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objectives The prognostic significance of the neutrophil‐to‐lymphocyte ratio (NLR) and tumor‐associated neutrophils (TANs) in head and neck squamous cell carcinoma (HNSCC) remains a subject of considerable research interest. This systematic review and meta‐analysis aimed to evaluate the relationship between pretreatment NLR and TANs and ...
Ahana Kapuge Dona Varuni Yashodha Ratnayake, Aini Hyytiäinen, Georgia Vasiliki Gkountana, Meri Torri, Ahmed Al‐Samadi   +4 more
wiley   +1 more source

Establishing C-X-C motif chemokine receptor 4 as a novel imaging target in giant cell arteritis. [PDF]

Arthritis Res Ther
Fröhlich M, Serfling SE, Gernert M, Guggenberger K, Higuchi T, Gerhard-Hartmann E, Weich A, Samnick S, Schmalzing M, Bley TA, Buck AK, Werner RA.   +11 more
europepmc   +1 more source

CXCR4 Gene Mutation [PDF]

, 2020
openaire   +1 more source

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice.

Proceedings of the National Academy of Sciences of the United States of America, 1998
Qing Ma, Daniel M Jones, P. Borghesani, R. Segal, T. Nagasawa, T. Kishimoto, R. Bronson, T. Springer   +7 more
semanticscholar   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Circulating soluble CXCR4 fails to differentiate subtypes of primary aldosteronism. [PDF]

J Endocr Soc
Chao W, Ren Y, Zou M, Tan L, Chen T.
europepmc   +1 more source

Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies

Psychiatry and Clinical Neurosciences, EarlyView.
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda, Michihiro Toritsuka, Hiroto Tamakoshi, Nakao Iwata, Manabu Makinodan   +4 more
wiley   +1 more source