Results 271 to 280 of about 16,264 (303)
Some of the next articles are maybe not open access.
Cyclic di-GMP Signaling in Bacillus subtilis
2020The ubiquitous second messenger bis-(3′-5′)-cyclic diguanosine monophosphate (cyclic di-GMP) plays a key role in regulating the transition from motility to sessility in bacteria. While cyclic di-GMP regulation is well studied in a number of Gram-negative bacteria, the physiological role of cyclic di-GMP in Gram-positive organisms is less characterized.
Cordelia A. Weiss, Wade C. Winkler
openaire +1 more source
Riboswitches That Sense Cyclic Di-GMP
2014Riboswitches are almost always located in the 5’ untranslated regions (UTRs) of messenger RNAs, where they typically control either transcription elongation or translation initiation of genes whose protein products synthesize or transport the regulatory ligand.
Elaine R. Lee +2 more
openaire +1 more source
Cyclic di-GMP Regulation of Gene Expression
2020Cyclic di-GMP is a nearly ubiquitous bacterial second messenger signaling molecule that links changes in environmental cues to the regulation of a myriad of phenotypes including but not limited to biofilm formation, motility, virulence, and DNA repair.
Meng-Lun Hsieh +2 more
openaire +1 more source
Rational Design of Fluorescent Biosensor for Cyclic di‐GMP
ChemBioChem, 2011Messenger bagged: The design of a fluorophore-labeled protein biosensor for the bacterial messenger cyclic di-GMP is described. The biosensor responds to c-di-GMP with sub-micromolar sensitivity in a real-time fashion. The biosensor can be used for enzyme assays for diguanylate cyclases and c-di-GMP phosphodiesterases as well as the high-throughput ...
Chun Loong, Ho +6 more
openaire +2 more sources
Cyclic di-GMP mediates Mycobacterium tuberculosis dormancy and pathogenecity
Tuberculosis, 2013Dormancy of Mycobacterium tuberculosis is likely to be a major cause of extended chemotherapeutic regimens and wide prevalence of tuberculosis. The molecular mechanisms underlying M. tuberculosis dormancy are not well understood. In this study, single-copy genes responsible for synthesis (dgc) and degradation (pde) of the ubiquitous bacterial second ...
Yuzhi, Hong +5 more
openaire +2 more sources
Cyclic Di-GMP Signaling and Host Immunity
2014Testing the hypothesis that cyclic Di-GMP (c-di-GMP) can be used clinically to inhibit infection, synthetic exogenous c-di-GMP was found not to be bactericidal or bacteriostatic but could significantly inhibit Staphylococcus aureus biofilm formation in vitro.
David K. R. Karaolis +1 more
openaire +1 more source
Cyclic di-GMP Signaling in Extreme Acidophilic Bacteria
2020Extreme acidophilic bacteria are a phylogenetically diverse group of microorganisms that grow optimally at pH values below 3. They thrive in natural or man-made environments where life is challenged by extreme acidity, low availability of organic matter, and high concentrations of heavy metals.
Matías Castro +3 more
openaire +1 more source
Methods for Cyclic Di-GMP Detection
2014The first decade of the 21st century has seen an explosion of interest in the bacterial second messenger signal cyclic di-GMP (c-di-GMP). The study of c-di-GMP during this period has been fueled by the development of methods to visualize and quantify this molecule.
openaire +1 more source
Regulation by Cyclic di-GMP in Myxococcus xanthus
2020Myxococcus xanthus has a complex lifecycle that is regulated by nutrient availability. In the presence of nutrients, M. xanthus cells grow, divide, and move to assemble into colonies that feed cooperatively either saprophytically or on prey. In response to starvation, a developmental program is initiated that culminates in formation of multicellular ...
María Pérez-Burgos +1 more
openaire +1 more source
Cyclic-di-GMP promotes bacteria–host association
Nature Microbiology, 2023Tory A. Hendry, Kelley A. Gallagher
openaire +2 more sources