Results 11 to 20 of about 121,650 (304)

<em>Bacillus anthracis</em> Edema Factor Substrate Specificity: Evidence for New Modes of Action [PDF]

Toxins, 2012
Since the isolation of <em>Bacillus anthracis</em> exotoxins in the 1960s, the detrimental activity of edema factor (EF) was considered as adenylyl cyclase activity only.
Roland Seifert, Stefan Dove, Martin Göttle   +2 more
doaj   +4 more sources

Cyclic nucleotide signalling in malaria parasites [PDF]

Open Biology, 2017
The cyclic nucleotides 3′, 5′-cyclic adenosine monophosphate (cAMP) and 3′, 5′-cyclic guanosine monophosphate (cGMP) are intracellular messengers found in most animal cell types.
David A. Baker, Laura G. Drought, Christian Flueck, Stephanie D. Nofal, Avnish Patel, Maria Penzo, Eloise M. Walker   +6 more
doaj   +4 more sources

Crosstalk between G-protein and Ca2+ pathways switches intracellular cAMP levels [PDF]

, 2001
Cyclic adenosine monophosphate and cyclic guanosine monophosphate are universal intracellular messengers whose concentrations are regulated by molecular networks comprised of different isoforms of the synthases adenylate cyclase or guanylate cyclase and ...
A Dietz, B Majorovits, D Lal, FT Avignone, G Heusser, HV Klapdor-Kleingrothaus, HV Klapdor-Kleingrothaus, HV Klapdor-Kleingrothaus, HV Klapdor-Kleingrothaus, HV Klapdor-Kleingrothaus, J Ellis, J Hellmig, JD Lewin, K Preese, L Baudis, L Baudis, OA Ponkratenko, P Belli, R Bernabei, R Gaitskell, R Schnee, v Bednyakov, WN Hess   +22 more
core   +2 more sources

Differences in growth and alkaline phosphatase activity between Microcystis aeruginosa and Chlorella pyrenoidosa in response to media with different organic phosphorus

Journal of Limnology, 2011
The growth of Microcystis aeruginosa and Chlorella pyrenoidosa in three dissolved organic phosphorus sources (glucose-1- phosphate, adenosine triphosphate, cyclic-adenosine monophosphate) were studied in cultures separated by a dialysis membrane. Results
Yang YU, Min ZHANG, Fanxiang KONG, Xiaoli SHI, Shanqin QIAN   +4 more
doaj   +1 more source

Antidepressant effect of electroacupuncture regulates signal targeting in the brain and increases brain-derived neurotrophic factor levels

Neural Regeneration Research, 2016
Electroacupuncture improves depressive behavior faster and with fewer adverse effects than antidepressant medication. However, the antidepressant mechanism of electroacupuncture remains poorly understood.
Dong-mei Duan, Ya Tu, Ping Liu, Shuang Jiao   +3 more
doaj   +1 more source

The role of Phosphodiesterase-1 and its natural product inhibitors in Alzheimer’s disease: A review

Frontiers in Pharmacology, 2022
Phosphodiesterase-1 (PDE1) is a versatile enzyme that has surprisingly received considerable attention as a possible therapeutic target in Alzheimer’s disease (AD) because it maintains the homeostasis of 3ʹ,5ʹ-cyclic adenosine monophosphate (cAMP) and 3ʹ,
Nazir Ahmad, Kaisun Nesa Lesa, Ari Sudarmanto, Nanang Fakhrudin, Nanang Fakhrudin, Zullies Ikawati   +5 more
doaj   +1 more source

Imaging of PDE2- and PDE3-Mediated cGMP-to-cAMP Cross-Talk in Cardiomyocytes

Journal of Cardiovascular Development and Disease, 2018
Cyclic nucleotides 3′,5′-cyclic adenosine monophosphate (cAMP) and 3′,5′-cyclic guanosine monophosphate (cGMP) are important second messengers that regulate cardiovascular function and disease by acting in discrete subcellular microdomains.
Nikoleta Pavlaki, Viacheslav O. Nikolaev
doaj   +1 more source

Effect of dietary fluorine from Araxá rock phosphate on the hepatic production of cyclic-adenosine monophosphate in broilers

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 1999
The cyclic adenosine 3’, 5’-monophosphate (cAMP) production was evaluated in liver thin sections of broiler chicks fed on a experimental diet containing bicalcium phosphate or Araxá rock phosphate (ARP) as source of P, with a high content of fluorine, at
M.J.M. Rezende, J.A.F. Veloso, R.M.M. Turchetti-Maia   +2 more
doaj   +1 more source

Cyclic AMP signalling in pancreatic islets [PDF]

, 2010
Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian, Ong, Wee Kiat, Pyne, Nigel J.   +2 more
core   +1 more source

"cAMP sponge": a buffer for cyclic adenosine 3', 5'-monophosphate. [PDF]

PLoS ONE, 2009
BACKGROUND:While intracellular buffers are widely used to study calcium signaling, no such tool exists for the other major second messenger, cyclic AMP (cAMP). METHODS/PRINCIPAL FINDINGS:Here we describe a genetically encoded buffer for cAMP based on the
Konstantinos Lefkimmiatis, Mary Pat Moyer, Silvana Curci, Aldebaran M Hofer   +3 more
doaj   +1 more source