Results 11 to 20 of about 32,383 (302)
Neuropsychiatric Disease and Treatment, 2015 Yu Zhao,1 Ming Xiao,2 Wenbo He,3 Zhiyou Cai3 1Department of Neurology, the Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China; 2Department of Anatomy, Nanjing Medical ...
Zhao Y, Xiao M, He W, Cai Z
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JCI Insight, 2021 Obesity, a major health care issue, is characterized by metabolic abnormalities in multiple tissues, including the skeletal muscle. Although dysregulation of skeletal muscle metabolism can strongly influence the homeostasis of systemic energy, the ...
Bo Xu +9 more
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Role of cyclic AMP in the control of cell-specific gene expression [PDF]
, 1993 Genes have to be expressed in specific cell types at appropriate times of development dependent on external signals. cAMP signaling occurs in all cells, thus raising the question of how this signal transduction pattern is integrated into mechanisms ...
Boshart, Michael +3 more
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Cell Reports, 2023 Summary: Remyelination after white matter injury (WMI) often fails in diseases such as multiple sclerosis because of improper recruitment and repopulation of oligodendrocyte precursor cells (OPCs) in lesions.
Kimberly K. Hoi +7 more
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Expression cloning of a zinc-finger cyclic AMP-response-element-binding protein [PDF]
Biochemical Journal, 1995 In response to specific extracellular signals, intracellular cyclic AMP levels increase, leading to a variety of responses including the alteration of transcription of many eukaryotic genes. This transcriptional effect is frequently mediated through the cyclic AMP-response element (CRE) motif T(T/G)ACGTCA. Using an expression screening approach we have
R M, O'Brien +4 more
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Resveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cells. [PDF]
PLoS ONE, 2012 BACKGROUND: Resveratrol is a natural polyphenolic compound that has cardioprotective, anticancer and anti-inflammatory properties. We investigated the capacity of resveratrol to protect RAW 264.7 cells from inflammatory insults and explored mechanisms ...
Yi Zong +10 more
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Regulation of cyclic AMP response element‐binding protein during neuroglial interactions [PDF]
Journal of Neurochemistry, 2016 AbstractCommunications between neurons and glial cells play an important role in regulating homeostasis in the central nervous system. cAMP response element‐binding protein (CREB), a transcription factor, is down‐regulated by neurotoxins, which are known to be released by activated glial cells.
LiMei, Qin +2 more
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A Pivotal Role of Cyclic AMP-Responsive Element Binding Protein in Tumor Progression [PDF]
Cancer Research, 2004 Abstract Tumor microenvironment controls the selection of malignant cells capable of surviving in stressful and hypoxic conditions. The transcription factor, cyclic AMP-responsive element binding (CREB) protein, activated by multiple extracellular signals, modulates cellular response by regulating the expression of a multitude of genes ...
Rinat, Abramovitch +8 more
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Neoplasia: An International Journal for Oncology Research, 2007 We recently showed that NexrutineR, a Phellodendron amurense bark extract, suppresses proliferation of prostate cancer cell lines and tumor development in the transgenic adenocarcinoma of mouse prostate (TRAMP) model.
Rita Ghosh +6 more
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Insights into the activation mechanism of PopA, a cyclic di-GMP effector protein involved in cell cycle and development of "Caulobacter Crescentus" [PDF]
, 2012 In Caulobacter crescentus, a complex network integrating cyclic di-GMP and Phosphorylation-dependent signals controls the proteolysis of key regulatory proteins to drive cell cycle and polar morphogenesis.
Schalch-Moser, Annina Larissa
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