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Total synthesis of antimicrobial and antitumor cyclic depsipeptides

Chemical Communications, 2010
The total synthesis of natural products "has to be viewed as an art and a science that needs to be advanced for its own sake" (K. C. Nicolaou) and indeed, the achievements within this field of chemistry during the last decades are astonishing. However, besides its inherent beauty, total synthesis also opens the gates widely to a better understanding of
Wenhua, Li   +2 more
openaire   +2 more sources

Cyclic Peptides and Depsipeptides from Fungi

2009
This chapter describes the occurrence of cyclic peptides and cyclic depsipeptides within the kingdom Eumycota (true fungi), the diversity of structures and their chemical building blocks, their ecological roles and their different biological activities.
Heidrun Anke, Luis Antelo
openaire   +1 more source

A Total Synthesis of the Cyclic Depsipeptide Chaiyaphumine‐A

ChemistrySelect, 2017
Abstract The first total synthesis of Chaiyaphumine‐A, a cyclic depsipentapeptide isolated from Xenorhabdus SP. PB614 which showed good activity against Plasmodium falcifarum (IC 50 = 0.61 μM ...
Somnath S. Gholap, Sandip R. Ugale
openaire   +1 more source

Chemistry and Biology of Cyclic Depsipeptides of Medicinal and Biological Interest

Current Medicinal Chemistry, 2004
Cyclodepsipeptides comprise a wide variety of cyclic peptides of natural origin and are characterized by the occurrence of at least one ester linkage. The great interest that this class of natural products has elicited in scientific community is explained by their wide range of biological activities, intriguing mechanisms of action and attractive ...
Francisco, Sarabia   +4 more
openaire   +2 more sources

Interaction of cyclic peptides and depsipeptides with calmodulin.

Peptide research, 1992
A variety of small peptides bind calmodulin (CaM) and inhibit CaM-dependent enzyme activity. The cyclic peptides cyclosporin A (CSA) and gramicidin-S (GRS) are shown to bind CaM and inhibit 3',5'-cyclic nucleotide phosphodiesterase (PDE) in a calcium-dependent manner.
K A, Mereish   +3 more
openaire   +1 more source

N-Methylsansalvamide, a cytotoxic cyclic depsipeptide from a marine fungus of the genus Fusarium

Phytochemistry, 2000
William Fenical   +2 more
exaly  

Total Synthesis of Halipeptin A: A Potent Antiinflammatory Cyclic Depsipeptide

Angewandte Chemie International Edition, 2004
Shouyun, Yu   +3 more
openaire   +2 more sources

Arthogalin, a Cyclic Depsipeptide from the Lichen Arthothelium galapagoense

Zeitschrift Fur Naturforschung - Section B Journal of Chemical Sciences, 1995
S Huneck
exaly  

METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES

2019
HEIMBACH DIRK   +11 more
openaire   +5 more sources

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