Results 121 to 130 of about 3,176 (160)
Arthogalin, a Cyclic Depsipeptide from the Lichen Arthothelium galapagoense
Zeitschrift Fur Naturforschung - Section B Journal of Chemical Sciences, 1995 The structure and stereochemistry of arthogalin from the liehen Arthothelium galapagoense has been elucidated as the cyclic depsipeptide 1′.
S Huneck, G Nicholson
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Chemistry and Biology of Cyclic Depsipeptides of Medicinal and Biological Interest
Current Medicinal Chemistry, 2004Cyclodepsipeptides comprise a wide variety of cyclic peptides of natural origin and are characterized by the occurrence of at least one ester linkage. The great interest that this class of natural products has elicited in scientific community is explained by their wide range of biological activities, intriguing mechanisms of action and attractive ...
Francisco, Sarabia +4 more
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Cyclic Peptides and Depsipeptides from Fungi
2009This chapter describes the occurrence of cyclic peptides and cyclic depsipeptides within the kingdom Eumycota (true fungi), the diversity of structures and their chemical building blocks, their ecological roles and their different biological activities.
Heidrun Anke, Luis Antelo
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New Cyclic Depsipeptide from an Endophytic Actinomycete
Chemistry of Natural Compounds, 2015A new sixteen-member cyclic depsipeptide, strepeptolide, was isolated from the culture broth of an endophytic actinomycetes strain. The structure of the compound was elucidated by detailed 1D, 2D NMR, HR-ESI-MS, and IR spectroscopic data.
Li Han, Yi-Qing Li, Li-Xing Zhao
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Total synthesis of an antifungal cyclic depsipeptide aureobasidin A
Tetrahedron, 1996Abstract The first total synthesis of antifungal cyclic depsipeptide aureobasidin A is described. The synthesis was achieved mainly using bromotris(pyrrolidino)phosphonium hexafluorophosphate (PyBroP) as a coupling reagent. Peptide cyclization was carried out between L- allo -isoleucine (L- a lle 1 ) and L- Pro 9 residues in the linear nonapeptide ...
Toru Kurome +6 more
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ChemInform Abstract: The Cyclic Depsipeptide Backbone of the Didemnins.
ChemInform, 1996AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
S. C. MAYER +2 more
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Asymmetric Total Syntheses of Marine Cyclic Depsipeptide Halipeptins A–D
Chemistry – A European Journal, 2006AbstractHalipeptins A–D (1 a–d) are a family of natural cyclic depsipeptides isolated from marine sponges. Total syntheses of these four compounds are detailed in this report. The key elements in this synthesis include the elaboration of the polysubstituted decanoic acid parts by two asymmetric aldol reactions, assembly of the N‐methyl‐δ ...
Shouyun, Yu, Xianhua, Pan, Dawei, Ma
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Rakicidin C, A New Cyclic Depsipeptide fromStreptomycessp.
European Journal of Organic Chemistry, 2000Chemical screening of extracts of Actinomycetes strains has led to the detection, isolation, and structure elucidation of the new cyclic depsipeptide rakicidin C (1). The secondary metabolite from Streptomyces sp. (strain GT 61042) is built-up from glutamine, N-methyl glycine, 4-amino-(2E,4)-pentadienoic acid, and 3-hydroxy-2,4,6,8-tetramethylnonanoic ...
Jin-Feng Hu +5 more
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Diverse Synthesis of Marine Cyclic Depsipeptide Lagunamide A and Its Analogues
The Journal of Organic Chemistry, 2013The asymmetric total synthesis of lagunamide A (3.0%, 20 steps longest linear sequence) and its five analogues, including the structure dehydrated at the C37 position, are detailed in this report. The key feature in this diverse synthesis includes the elaboration of four consecutive chiral centers at C37-40 and the final macrocyclization. Starting from
Wei, Huang +4 more
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Cyclic Carbo-Isosteric Depsipeptides and Peptides as a Novel Class of Peptidomimetics
Organic Letters, 2014A novel and highly efficient cyclization method has been developed to access a new class of cyclic carbo-isosteric depsipeptides and carbo-isosteric peptides. Our strategy requires easily accessible C-terminal methyl ketone ester or amide functionalized linear precursors as starting materials.
Stéphanie M, Guéret +2 more
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