Results 31 to 40 of about 3,681 (193)

Insights into the Antimicrobial Activities and Metabolomes of Aquimarina (Flavobacteriaceae, Bacteroidetes) Species from the Rare Marine Biosphere

Marine Drugs, 2022
Two novel natural products, the polyketide cuniculene and the peptide antibiotic aquimarin, were recently discovered from the marine bacterial genus Aquimarina.
Sandra Godinho Silva, Patrícia Paula, José Paulo da Silva, Dalila Mil-Homens, Miguel Cacho Teixeira, Arsénio Mendes Fialho, Rodrigo Costa, Tina Keller-Costa   +7 more
doaj   +1 more source

Szentiamide, an -formylated Cyclic Depsipeptide from DSM 16338

Natural Product Communications, 2011
Szentiamide ( 1 ) a new cyclic hexadepsipeptide was isolated from the culture broth of the entomopathogenic bacterium Xenorhabdus szentirmaii DSM 16338 T .
Birgit Ohlendorf, Sven Simon, Jutta Wiese, Johannes F. Imhoff   +3 more
doaj   +1 more source

Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA)

Pharmaceutics, 2018
Teixobactin is a highly potent cyclic depsipeptide which kills a broad range of multi-drug resistant, Gram-positive bacteria, such as Methicillin-resistant Staphylococcus aureus (MRSA) without detectable resistance.
Ruba Malkawi, Abhishek Iyer, Anish Parmar, Daniel G. Lloyd, Eunice Tze Leng Goh, Edward J. Taylor, Sarir Sarmad, Annemieke Madder, Rajamani Lakshminarayanan, Ishwar Singh   +9 more
doaj   +1 more source

Unprecedented Antimicrobial and Cytotoxic Polyketides from Cultures of Diaporthe africana sp. nov.

Journal of Fungi, 2023
Four unprecedented polyketides named isoprenylisobenzofuran B (2), isoprenylisobenzofuran C1/C2 (3), diaporisoindole F1/F2 (4), and isochromophilonol A1/A2 (7) were isolated from ethyl acetate extracts of the newly described endophytic fungus Diaporthe ...
Blondelle Matio Kemkuignou, Christopher Lambert, Marc Stadler, Simeon Kouam Fogue, Yasmina Marin-Felix   +4 more
doaj   +1 more source

Revised Structure of Cyclolithistide A, a Cyclic Depsipeptide from the Marine Sponge Discodermia japonica [PDF]

, 2016
A cyclic peptide was isolated from the deep-sea marine sponge Discodermia japonica, and its NMR spectroscopic data were identical to those reported for cyclolithistide A, a known antifungal depsipeptide.
Kentaro Takada (1476262), Yuji Ise (1476268), Hiroki Tajima (1854154), Toshiyuki Wakimoto (1452055), Ikuro Abe (1433923)   +4 more
core   +1 more source

SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A.

PLoS ONE, 2016
In order to expand the repertoire of antifungal compounds a novel, high-throughput phenotypic drug screen targeting fungal phosphatidylserine (PS) synthase (Cho1p) was developed based on antagonism of the toxin papuamide A (Pap-A).
Chelsi D Cassilly, Marcus M Maddox, Philip T Cherian, John J Bowling, Mark T Hamann, Richard E Lee, Todd B Reynolds   +6 more
doaj   +1 more source

Ulongapeptin, a Cytotoxic Cyclic Depsipeptide from a Palauan Marine Cyanobacterium Lyngbya sp. [PDF]

, 2016
Ulongapeptin (1), a cyclic depsipeptide, was isolated from a Palauan marine cyanobacterium Lyngbya sp. The gross structure was elucidated through one-dimensional TOCSY experiments and other spectroscopic techniques.
Wesley Y. Yoshida (1265682), Valerie J. Paul (307783), Philip G. Williams (307047), Richard E. Moore (2709358), Michael K. Quon (2728150)   +4 more
core   +1 more source

Characterizing the Anti-HIV Activity of Papuamide A

Marine Drugs, 2008
Papuamide A is representative of a class of marine derived cyclic depsipeptides, reported to have cytoprotective activity against HIV-1 in vitro. We show here that papuamide A acts as an entry inhibitor, preventing human immunodeficiency virus infection ...
Louis R. Barrows, Vicente Planelles, Cynthia D. Andjelic   +2 more
doaj   +1 more source

Bioactivities of Lyngbyabellins from Cyanobacteria of Moorea and Okeania Genera

Molecules, 2020
Cyanobacteria are reported as rich sources of secondary metabolites that provide biological activities such as enzyme inhibition and cytotoxicity. Ten depsipeptide derivatives (lyngbyabellins) were isolated from a Malaysian Moorea bouillonii and a Red ...
Imam Fathoni, Julie G. Petitbois, Walied M. Alarif, Ahmed Abdel-Lateff, Sultan S. Al-Lihaibi, Erina Yoshimura, Yasuyuki Nogata, Charles S. Vairappan, Eti Nurwening Sholikhah, Tatsufumi Okino   +9 more
doaj   +1 more source

Isolation of Heptadepsin, a Novel Bacterial Cyclic Depsipeptide that Inhibits Lipopolysaccharide Activity [PDF]

, 2004
Lipopolysaccharide (LPS) is considered to cause various inflammatory reactions. We searched among microbial secondary metabolites for compounds that could inhibit LPS-stimulated adhesion between human umbilical vein endothelial cells (HUVEC) and human ...
Miyake, Kensuke, Osamu Ohno, Kensuke Miyake, Igarashi, Masayuki, Sawa, Ryuichi, Kinoshita, Naoko, Yoko Ikeda, Masayuki Igarashi, Kazuo Umezawa, Naoko Kinoshita, Ikeda, Yoko, Suzuki, Yoshikazu, Ohno, Osamu, Ryuichi Sawa, Yoshikazu Suzuki, Umezawa, Kazuo   +15 more
core   +1 more source