Results 11 to 20 of about 3,681 (193)
Optimized SPE–UPLC–MS/MS Method for Sensitive Determination of Cereulide in Complex InfantFormula Matrices [PDF]
ToxinsCereulide is a heat-stable cyclic depsipeptide toxin produced by Bacillus cereus and is responsible for foodborne emetic syndrome. Recent reports of Bacillus cereus contamination and cereulide occurrence in infant formula have raised increasing food ...
Zixiao Zhou +8 more
doaj +2 more sources
Lyngbyastatins 8–10, Elastase Inhibitors with Cyclic Depsipeptide Scaffolds Isolated from the Marine Cyanobacterium Lyngbya semiplena [PDF]
Marine Drugs, 2009 Investigation of an extract from the marine cyanobacterium Lyngbya semiplena, collected in Tumon Bay, Guam, led to the identification of three new cyclodepsipeptides, lyngbyastatins 8–10 (1–3).
Hendrik Luesch +3 more
doaj +2 more sources
A cyclic carbo-isosteric penta-depsipeptide: cyclo(Phe1–d-Ala2–Gly3–Phe4–APO5) [PDF]
Acta Crystallographica Section E: Crystallographic Communications, 2015 The title compound, cyclo(Phe1–d-Ala2–Gly3–Phe4–APO5), C26H32N4O5, is the minor diastereoisomer of a cyclic penta-peptidomimetic analogue containing a novel 2-aminopropyl lactone (APO) motif, which displays the same number of atoms as the native amino ...
Stéphanie M. Guéret, Trixie Wagner
doaj +4 more sources
Adsorption of cyclic depsipeptide mycotoxins to glass [PDF]
, 2014 During analytical processes, adsorption of peptides, which is believed to mostly be due to non-covalent interactions and depending upon the experimental conditions, cannot only lead to significant loss of the analyte, but also to increased analytical variability. This undesirable aspect, however, has been given scant attention [1-2].
Taevernier, Lien +2 more
openaire +2 more sources
Structural and functional studies of cyclic depsipeptide biosynthesis [PDF]
, 2019 Cyclic depsipeptides, ubiquitous natural products of industrial and medical importance, are produced by nonribosomal peptide synthetases (NRPS) using a diverse repertoire of biosynthetic mechanisms. For instance, cereulide (Ces) and valinomycin (Vlm) depsipeptide synthetases generate a linear precursor by the alternate condensation of hydroxy and amino
Alonzo Muniz, Diego
openaire +2 more sources
Human skin kinetics of cyclic depsipeptide mycotoxins [PDF]
, 2014 Cyclic depsipeptides (CDPs) are an emerging group of naturally occurring bioactive peptides, some of which are already developed as pharmaceutical drugs, e.g. valinomycin. They are produced by bacteria, marine organisms and fungi [1]. Some CDPs are secondary fungal metabolites, which can be very toxic to humans and animals, and are therefore called ...
Taevernier, Lien +3 more
openaire +2 more sources
Pagoamide A, a Cyclic Depsipeptide Isolated from a Cultured Marine Chlorophyte, Derbesia sp., Using MS/MS-Based Molecular Networking. [PDF]
J Nat Prod, 2020 A thiazole-containing cyclic depsipeptide with 11 amino acid residues, named pagoamide A (1), was isolated from laboratory cultures of a marine Chlorophyte, Derbesia sp.
Li Y +14 more
europepmc +5 more sources
Discovery of a Cyclic Depsipeptide from Chaetomium mollipilium by the Genome Mining Approach [PDF]
, 2022 Genome mining and bioinformatics analyses allowed us to rationally find a candidate biosynthetic gene cluster for a new cyclic depsipeptide of Chaetomium mollipilium.
Taro Ozaki (823047) +11 more
core +1 more source
Total Synthesis of Pagoamide A
Molecules, 2021 The first total synthesis of the thiazole-containing cyclic depsipeptide pagoamide A, is detailed. The longest linear sequence of the liquid-phase synthesis comprises 9 long linear steps from simple known starting materials, which led to the unambiguous ...
Fusong Wu +4 more
doaj +1 more source
Pathogens, 2020 Fungi from the Hypocreales order synthesize a range of toxic non-ribosomal cyclic peptides with antimicrobial, insecticidal and cytotoxic activities. Entomopathogenic Beauveria, Isaria and Cordyceps as well as phytopathogenic Fusarium spp.
Monika Urbaniak +4 more
doaj +1 more source