Results 11 to 20 of about 433,171 (190)

Adsorption of cyclic depsipeptide mycotoxins to glass [PDF]

, 2014
During analytical processes, adsorption of peptides, which is believed to mostly be due to non-covalent interactions and depending upon the experimental conditions, cannot only lead to significant loss of the analyte, but also to increased analytical variability. This undesirable aspect, however, has been given scant attention [1-2].
Taevernier, Lien, Vansteelandt, Stijn, De Spiegeleer, Bart   +2 more
openaire   +2 more sources

Cyclic Thiosulfinates: Synthesis and Applications in Chemical Biology and Materials Science. [PDF]

Chembiochem
Cyclic thiosulfinates (CTs) are strained organosulfur heterocyclic compounds with a polarized ─S(═O)─S─ bond that enables selective thiol reactivity. Advances in synthesis afford tunable scaffolds that support efficient proximal thiol cross‐linking and enable applications in chemical biology and materials science. Cyclic thiosulfinates (CTs) constitute
Liebson B, Agar JN, Manetsch R, Parvatkar PT.   +3 more
europepmc   +2 more sources

Discovery of a Cyclic Depsipeptide from Chaetomium mollipilium by the Genome Mining Approach

, 2022
Genome mining and bioinformatics analyses allowed us to rationally find a candidate biosynthetic gene cluster for a new cyclic depsipeptide of Chaetomium mollipilium.
Taro Ozaki (823047), Taro Ozaki, Yuto Homma, Yohei Morishita, Akihiro Sugawara (198459), Yohei Morishita (5819357), Teigo Asai, Kento Tsukada (11982020), Teigo Asai (1915987), Kento Tsukada, Yuto Homma (12529891), Akihiro Sugawara   +11 more
core   +1 more source

Actinomycin Derivatives: Structural Diversification and Biological Activities. [PDF]

ChemMedChem
Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Can Ö, Bedir E.
europepmc   +2 more sources

Acetylation of FoxO1 Activates Bim Expression to Induce Apoptosis in Response to Histone Deacetylase Inhibitor Depsipeptide Treatment

Neoplasia: An International Journal for Oncology Research, 2009
Histone deacetylase (HDAC) inhibitors have been shown to induce cell cycle arrest and apoptosis in cancer cells. However, the mechanisms of HDAC inhibitor induced apoptosis are incompletely understood. In this study, depsipeptide, a novel HDAC inhibitor,
Yang Yang, Ying Zhao, Wenjuan Liao, Jing Yang, Lipeng Wu, Zhixing Zheng, Yu Yu, Wen Zhou, Lian Li, Jingnan Feng, Haiying Wang, Wei-Guo Zhu   +11 more
doaj   +1 more source

Chemical Classification of Cyclic Depsipeptides

Current Protein & Peptide Science, 2017
Cyclic depsipeptides (CDPs) are a family of cyclic peptide-related compounds, of which the ring is mainly composed of amino- and hydroxy acid residues joined by amide and ester bonds (at least one), leading to a wide diversity of fascinating chemical structures. They differ in both their ring structure and their side chains, especially by the nature of
Taevernier, Lien, Wynendaele, Evelien, Gevaert, Bert, De Spiegeleer, Bart   +3 more
openaire   +3 more sources

Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids

Beilstein Journal of Organic Chemistry, 2014
The synthesis of six cyclic depsipeptoids inspired by the natural depsipeptide sansalvamide A is described. An efficient and fast synthetic strategy was developed using a combination of consecutive isocyanide-based multicomponent reactions (Ugi and ...
Angélica de Fátima S. Barreto, Otilie E. Vercillo, Ludger A. Wessjohann, Carlos Kleber Z. Andrade   +3 more
doaj   +1 more source

Identification of 2,4-diacetylphloroglucinol production in the genus Chromobacterium

Scientific Reports, 2023
The compound 2,4-diacetylphloroglucinol (DAPG) is a broad-spectrum antibiotic that is primarily produced by Pseudomonas spp. DAPG plays an important role in the biocontrol disease suppressing activity of Pseudomonas spp.
Eric T. Johnson, Michael J. Bowman, Raylane Pereira Gomes, Lilian Carla Carneiro, Christopher A. Dunlap   +4 more
doaj   +1 more source

Characterisation of the Antibiotic Profile of Lysobacter capsici AZ78, an Effective Biological Control Agent of Plant Pathogenic Microorganisms

Microorganisms, 2021
Determining the mode of action of microbial biocontrol agents plays a key role in their development and registration as commercial biopesticides. The biocontrol rhizobacterium Lysobacter capsici AZ78 (AZ78) is able to inhibit a vast array of plant ...
Francesca Brescia, Anthi Vlassi, Ana Bejarano, Bernard Seidl, Martina Marchetti-Deschmann, Rainer Schuhmacher, Gerardo Puopolo   +6 more
doaj   +1 more source

Insights into the Antimicrobial Activities and Metabolomes of Aquimarina (Flavobacteriaceae, Bacteroidetes) Species from the Rare Marine Biosphere

Marine Drugs, 2022
Two novel natural products, the polyketide cuniculene and the peptide antibiotic aquimarin, were recently discovered from the marine bacterial genus Aquimarina.
Sandra Godinho Silva, Patrícia Paula, José Paulo da Silva, Dalila Mil-Homens, Miguel Cacho Teixeira, Arsénio Mendes Fialho, Rodrigo Costa, Tina Keller-Costa   +7 more
doaj   +1 more source