Chemical Classification of Cyclic Depsipeptides
Cyclic depsipeptides (CDPs) are a family of cyclic peptide-related compounds, of which the ring is mainly composed of amino- and hydroxy acid residues joined by amide and ester bonds (at least one), leading to a wide diversity of fascinating chemical structures. They differ in both their ring structure and their side chains, especially by the nature of
Taevernier, Lien +3 more
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Coibamide A, a Potent Antiproliferative Cyclic Depsipeptide from the Panamanian Marine Cyanobacterium Leptolyngbya sp. [PDF]
Coibamide A, a Potent Antiproliferative Cyclic Depsipeptide from the Panamanian Marine Cyanobacterium Leptolyngbya ...
Luz I. Romero (2417095) +8 more
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Total Synthesis of the Marine Cyclic Depsipeptide Viequeamide A [PDF]
The first total synthesis of viequeamide A, a natural cyclic depsipeptide isolated from a marine button cyanobacterium, was achieved with the N-Me-Val–Thr peptide bond as the final macrocyclization site.
Zehong Miao (1655995) +5 more
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Multicomponent Synthesis of Cyclic Depsipeptide Mimics by Ugi Reaction Including Cyclic Hemiacetals Derived from Asymmetric Organocatalysis [PDF]
The synthesis of novel cyclic depsipeptide mimics by means of an organocatalytic conjugate addition, leading to chiral cyclic hemiacetals, followed by a multicomponent reaction with α-amino acids and isocyanides, is described. The initial organocatalytic
Odette Concepción (1392715) +5 more
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Kahalalide K: A New Cyclic Depsipeptide from the Hawaiian Green Alga Bryopsis Species [PDF]
Kahalalide K (1), a new cyclic depsipeptide, was isolated from the Hawaiian green alga Bryopsis sp. Kahalalide K was determined to possess a new array of three l- and three d-amino acids, including a 3-hydroxy-9-methyldecanoic acid that had been ...
Bryan Sakamoto (2348320) +4 more
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Total Synthesis and Assignment of the Side Chain Stereochemistry of LI-F04a: An Antimicrobial Cyclic Depsipeptide [PDF]
The total synthesis of the potent antifungal and antibiotic cyclic depsipeptide LI-F04a and its side chain epimer was accomplished using macrolactonization to assemble the cyclic peptide core, followed by attachment of the 15-guanidino-3 ...
Katrina A. Jolliffe (401409) +2 more
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Identification of 2,4-diacetylphloroglucinol production in the genus Chromobacterium
The compound 2,4-diacetylphloroglucinol (DAPG) is a broad-spectrum antibiotic that is primarily produced by Pseudomonas spp. DAPG plays an important role in the biocontrol disease suppressing activity of Pseudomonas spp.
Eric T. Johnson +4 more
doaj +1 more source
Georgamide, a New Cyclic Depsipeptide with an Alkynoic Acid Residue from an Australian Cyanobacterium [PDF]
A cyclic depsipeptide, georgamide (1), was isolated from an Australian cyanobacterium and characterized by spectroscopic means. The constituent units were five amino acid residues, one each of l-Thr, l-Pro, l-Val, N-Me-l-Val, and N-Me-l-Phe, and two ...
Karen L. Erickson (2254336) +1 more
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Determining the mode of action of microbial biocontrol agents plays a key role in their development and registration as commercial biopesticides. The biocontrol rhizobacterium Lysobacter capsici AZ78 (AZ78) is able to inhibit a vast array of plant ...
Francesca Brescia +6 more
doaj +1 more source
Total Synthesis and Cytotoxicity Studies of a Cyclic Depsipeptide with Proposed Structure of Palau'amide [PDF]
Total synthesis of a cyclic depsipeptide with proposed structure of palau'amide is achieved, which features a stereoselective elaboration of its 5,7-dihydroxy-2,6-dimethyldodec-2-en-11-ynoic acid unit.
Bin Zou (539731) +2 more
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