Results 21 to 30 of about 433,171 (190)

Szentiamide, an -formylated Cyclic Depsipeptide from DSM 16338

Natural Product Communications, 2011
Szentiamide ( 1 ) a new cyclic hexadepsipeptide was isolated from the culture broth of the entomopathogenic bacterium Xenorhabdus szentirmaii DSM 16338 T .
Birgit Ohlendorf, Sven Simon, Jutta Wiese, Johannes F. Imhoff   +3 more
doaj   +1 more source

Cyclic J integral using linear matching method [PDF]

, 2012
The extended version of the latest Linear Matching Method (LMM) has the capability to evaluate the stable cyclic response, which produces cyclic stresses, residual stresses and plastic strain ranges for the low cycle fatigue assessment with cyclic load ...
Chen, Haofeng, Chen, Weihang
core   +3 more sources

Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA)

Pharmaceutics, 2018
Teixobactin is a highly potent cyclic depsipeptide which kills a broad range of multi-drug resistant, Gram-positive bacteria, such as Methicillin-resistant Staphylococcus aureus (MRSA) without detectable resistance.
Ruba Malkawi, Abhishek Iyer, Anish Parmar, Daniel G. Lloyd, Eunice Tze Leng Goh, Edward J. Taylor, Sarir Sarmad, Annemieke Madder, Rajamani Lakshminarayanan, Ishwar Singh   +9 more
doaj   +1 more source

Unprecedented Antimicrobial and Cytotoxic Polyketides from Cultures of Diaporthe africana sp. nov.

Journal of Fungi, 2023
Four unprecedented polyketides named isoprenylisobenzofuran B (2), isoprenylisobenzofuran C1/C2 (3), diaporisoindole F1/F2 (4), and isochromophilonol A1/A2 (7) were isolated from ethyl acetate extracts of the newly described endophytic fungus Diaporthe ...
Blondelle Matio Kemkuignou, Christopher Lambert, Marc Stadler, Simeon Kouam Fogue, Yasmina Marin-Felix   +4 more
doaj   +1 more source

Isolation of Heptadepsin, a Novel Bacterial Cyclic Depsipeptide that Inhibits Lipopolysaccharide Activity [PDF]

, 2004
Lipopolysaccharide (LPS) is considered to cause various inflammatory reactions. We searched among microbial secondary metabolites for compounds that could inhibit LPS-stimulated adhesion between human umbilical vein endothelial cells (HUVEC) and human ...
Miyake, Kensuke, Osamu Ohno, Kensuke Miyake, Igarashi, Masayuki, Sawa, Ryuichi, Kinoshita, Naoko, Yoko Ikeda, Masayuki Igarashi, Kazuo Umezawa, Naoko Kinoshita, Ikeda, Yoko, Suzuki, Yoshikazu, Ohno, Osamu, Ryuichi Sawa, Yoshikazu Suzuki, Umezawa, Kazuo   +15 more
core   +1 more source

SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A.

PLoS ONE, 2016
In order to expand the repertoire of antifungal compounds a novel, high-throughput phenotypic drug screen targeting fungal phosphatidylserine (PS) synthase (Cho1p) was developed based on antagonism of the toxin papuamide A (Pap-A).
Chelsi D Cassilly, Marcus M Maddox, Philip T Cherian, John J Bowling, Mark T Hamann, Richard E Lee, Todd B Reynolds   +6 more
doaj   +1 more source

Characterizing the Anti-HIV Activity of Papuamide A

Marine Drugs, 2008
Papuamide A is representative of a class of marine derived cyclic depsipeptides, reported to have cytoprotective activity against HIV-1 in vitro. We show here that papuamide A acts as an entry inhibitor, preventing human immunodeficiency virus infection ...
Louis R. Barrows, Vicente Planelles, Cynthia D. Andjelic   +2 more
doaj   +1 more source

Bioactivities of Lyngbyabellins from Cyanobacteria of Moorea and Okeania Genera

Molecules, 2020
Cyanobacteria are reported as rich sources of secondary metabolites that provide biological activities such as enzyme inhibition and cytotoxicity. Ten depsipeptide derivatives (lyngbyabellins) were isolated from a Malaysian Moorea bouillonii and a Red ...
Imam Fathoni, Julie G. Petitbois, Walied M. Alarif, Ahmed Abdel-Lateff, Sultan S. Al-Lihaibi, Erina Yoshimura, Yasuyuki Nogata, Charles S. Vairappan, Eti Nurwening Sholikhah, Tatsufumi Okino   +9 more
doaj   +1 more source

Synthesis of szentiamide, a depsipeptide from entomopathogenic Xenorhabdus szentirmaii with activity against Plasmodium falciparum

Beilstein Journal of Organic Chemistry, 2012
The synthesis of the recently characterized depsipeptide szentiamide (1), which is produced by the entomopathogenic bacterium Xenorhabdus szentirmaii, is described. Whereas no biological activity was previously identified for 1, the material derived from
Friederike I. Nollmann, Andrea Dowling, Marcel Kaiser, Klaus Deckmann, Sabine Grösch, Richard ffrench-Constant, Helge B. Bode   +6 more
doaj   +1 more source

Discovery of a gene cluster for the biosynthesis of novel cyclic peptide compound, KK-1, in Curvularia clavata

Frontiers in Fungal Biology, 2023
KK-1, a cyclic depsipeptide with 10 residues produced by a filamentous fungus Curvularia clavata BAUA-2787, is a promising pesticide active compound with high activity against many plant pathogens, especially Botrytis cinerea.
Shigenari Yamaguchi, Tomonori Fujioka, Akira Yoshimi, Akira Yoshimi, Toshitaka Kumagai, Maiko Umemura, Keietsu Abe, Keietsu Abe, Masayuki Machida, Masayuki Machida, Kiyoshi Kawai   +10 more
doaj   +1 more source