Results 21 to 30 of about 1,254,991 (185)

Bright Side of Fusarium oxysporum: Secondary Metabolites Bioactivities and Industrial Relevance in Biotechnology and Nanotechnology

Journal of Fungi, 2021
Fungi have been assured to be one of the wealthiest pools of bio-metabolites with remarkable potential for discovering new drugs. The pathogenic fungi, Fusarium oxysporum affects many valuable trees and crops all over the world, producing wilt.
Sabrin R. M. Ibrahim, Alaa Sirwi, Basma G. Eid, Shaimaa G. A. Mohamed, Gamal A. Mohamed   +4 more
doaj   +1 more source

Biologically active cyclic depsipeptides from marine cyanobacteria [PDF]

This thesis describes the chemical investigation of marine cyanobacteria collected in Madagascar and Panama with an emphasis on the isolation and structure elucidation of medicinally relevant secondary metabolites.
Medina, Rebecca A.
core   +6 more sources

Stereocalpin B, a New Cyclic Depsipeptide from the Antarctic Lichen Ramalina terebrata

Metabolites, 2022
Stereocalpin B, a new cyclic depsipeptide (1), and a new dibenzofuran derivative (3), were isolated from the Antarctic lichen, Ramalina terebrata (Ramalinaceae), along with a known cyclic depsipeptide (2).
Seulah Lee, Se Yun Jeong, Dieu Linh Nguyen, Jae Eun So, Ki Hyun Kim, Ji Hee Kim, Se Jong Han, Sung-Suk Suh, Jun Hyuck Lee, Ui Joung Youn   +9 more
doaj   +1 more source

Cyclic Octamer Peptoids: Simplified Isosters of Bioactive Fungal Cyclodepsipeptides

Molecules, 2018
Cyclic peptoids have recently emerged as an important class of bioactive scaffolds with unique conformational properties and excellent metabolic stabilities.
Assunta D’Amato, Giorgio Della Sala, Irene Izzo, Chiara Costabile, Yuichi Masuda, Francesco De Riccardis   +5 more
doaj   +1 more source

Virtual Prospection of Marine Cyclopeptides as Therapeutics by Means of Conceptual DFT and Computational ADMET

Pharmaceuticals, 2022
Bioactive peptides are chemical compounds created through the covalent bonding of amino acids, known as amide or peptide bonds. Due to their unusual chemistry and various biological effects, marine bioactive peptides have garnered considerable research ...
Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik   +2 more
doaj   +1 more source

Synthesis of 16-membered cyclic depsipeptides via direct amide cyclization [PDF]

, 2000
The 2,2-disubstituted 2H-azirin-3-amines 5 (3-amino-2H-azirines) were used as synthons for alpha,alpha-disubstituted alpha-amino acids in the preparation of 16-membered cyclic depsipeptides 13.
Linden, Anthony; https://orcid.org/, Zass, Engelbert, Dunitz, Jack D., Gademann, Karl, MORINI, Giuseppina, Nangia, Ashwini, Molisho, N., Felderhoff, M., CENA C., MEDANA C., Seebach, Dieter, Walder, L., BERTINARIA M., ADAMI, Maristella, Hoyer, Daniel, SORBA G., Webersinn, S., Ernst, Martin, POZZOLI, Cristina, Desiraju, Gautam R., Koch, Kristian N, Heimgartner, Heinz, Heinen, S., Sarma, Jagarlapudi A. R. P., GASCO A., CORUZZI G.   +25 more
core   +1 more source

Metabolities from Marine Sponges of the Genus Callyspongia: Occurrence, Biological Activity, and NMR Data

Marine Drugs, 2021
The genus Callyspongia (Callyspongiidae) encompasses a group of demosponges including 261 described species, of which approximately 180 have been accepted after taxonomic reviews.
Lucas Hilário Nogueira de Sousa, Rusceli Diego de Araújo, Déborah Sousa-Fontoura, Fabrício Gava Menezes, Renata Mendonça Araújo   +4 more
doaj   +1 more source

Swinhopeptolides A and B: Cyclic Depsipeptides from the Sponge Theonella swinhoei that Inhibit Ras/Raf Interaction

Journal of Natural Products, 2020
Two new cyclic depsipeptides named swinhopeptolides A (1) and B (2), have been isolated from the marine sponge Theonella swinhoei cf. verrucosa, collected from Papua New Guinea.
Chang-Kwon Kim, Dongdong Wang, Heidi R. Bokesch, R. Fuller, Emily A. Smith, C. J. Henrich, David E. Durrant, D. Morrison, C. Bewley, K. Gustafson   +9 more
semanticscholar   +1 more source

Enhanced Ohmyungsamycin A Production via Adenylation Domain Engineering and Optimization of Culture Conditions

Frontiers in Microbiology, 2021
Ohmyungsamycins (OMSs) A and B are cyclic depsipeptides produced by marine Streptomyces strains, which are synthesized by a non-ribosomal peptide synthetase. Notably, OMS A exhibits more potent activity against Mycobacterium tuberculosis and human cancer
Eunji Kim, Young Eun Du, Yeon Hee Ban, Yern-Hyerk Shin, Dong-Chan Oh, Yeo Joon Yoon   +5 more
doaj   +1 more source

Protozoan-induced regulation of cyclic lipopeptide biosynthesis Is an effective predation defense mechanism for Pseudomonas fluorescens [PDF]

, 2009
Environmental bacteria are exposed to a myriad of biotic interactions that influence their function and survival. The grazing activity of protozoan predators significantly impacts the dynamics, diversification, and evolution of bacterial communities in ...
de Bruijn, Irene, Mazzola, M., Mazzola, Mark, Bruijn, I., de, Cohen, Michael F, Cohen, M.F., Raaijmakers, Jos M, Raaijmakers, J.M., de Bruijn, I.   +8 more
core   +1 more source