Solid-Phase Synthesis of Cyclic Depsipeptides Containing a Tyrosine Phenyl Ester Bond
The first solid-phase strategy for the synthesis of cyclic depsipeptides containing a phenyl ester linkage in their structure is described. The key steps of the synthesis were the formation of the phenyl ester bond and the on-resin head-to-side-chain ...
Kristy Vogels (2918675) +4 more
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Lagunamides A (<strong>1</strong>) and B (<strong>2</strong>) are potent cytotoxic cyclic depsipeptides isolated from the filamentous marine cyanobacterium, <em>Lyngbya majuscula</em>, from Pulau Hantu, Singapore ...
David Tai Leong +3 more
doaj +1 more source
Cyclodepsipeptides from Marine Sponges: Natural Agents for Drug Research
A number of natural products from marine sponges, such as cyclodepsipeptides, have been identified. The structural characteristics of this family of cyclic peptides include various unusual amino acid residues and unique N-terminal polyketide-derived ...
Rosa Lemmens-Gruber +1 more
doaj +1 more source
Fig. 2 in Trikoveramides A-C, cyclic depsipeptides from the marine cyanobacterium Symploca hydnoides
Fig. 2. Mass spectrometric fragmentation of trikoveramides A (1) – C (3).Published as part of Phyo, Ma Yadanar, Katermeran, Nursheena Parveen, Goh, Jun Xian & Tan, Lik Tong, 2021, Trikoveramides A-C, cyclic depsipeptides from the marine cyanobacterium ...
Tan, Lik Tong +3 more
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Metabolomics reveals the heterogeneous secretome of two entomopathogenic fungi to ex vivo cultured insect tissues. [PDF]
Fungal entomopathogens rely on cellular heterogeneity during the different stages of insect host infection. Their pathogenicity is exhibited through the secretion of secondary metabolites, which implies that the infection life history of this group of ...
Charissa de Bekker +3 more
doaj +1 more source
Peptides from Marine-Derived Fungi: Chemistry and Biological Activities
Marine natural products are well-recognized as potential resources to fill the pipeline of drug leads to enter the pharmaceutical industry. In this circumstance, marine-derived fungi are one of the unique sources of bioactive secondary metabolites due to
Salar Hafez Ghoran +4 more
doaj +1 more source
Protozoan-induced regulation of cyclic lipopeptide biosynthesis Is an effective predation defense mechanism for Pseudomonas fluorescens [PDF]
Environmental bacteria are exposed to a myriad of biotic interactions that influence their function and survival. The grazing activity of protozoan predators significantly impacts the dynamics, diversification, and evolution of bacterial communities in ...
de Bruijn, Irene +8 more
core +1 more source
Evidence for Ion-Templation During Macrocyclooligomerization of Depsipeptides
The ion-mediated Mitsunobu macrocyclooligomerization (M-MCO) reaction of hydroxy acid depsipeptides provides small collections of cyclic depsipeptides with good mass recovery.
Suzanne M. Batiste (4994918) +1 more
core +2 more sources
Lagunamide D, a new cytotoxic macrocyclic depsipeptide, was discovered from a collection of marine cyanobacteria from Loggerhead Key in the Dry Tortugas, Florida.
Danmeng Luo +4 more
doaj +1 more source
Production of destruxins from Metarhizium spp. fungi in artificial medium and in endophytically colonized cowpea plants. [PDF]
Destruxins (DTXs) are cyclic depsipeptides produced by many Metarhizium isolates that have long been assumed to contribute to virulence of these entomopathogenic fungi.
Patrícia S Golo +8 more
doaj +1 more source

