Results 21 to 30 of about 1,844 (163)

mMass as a software tool for the annotation of cyclic peptide tandem mass spectra. [PDF]

PLoS ONE, 2012
Natural or synthetic cyclic peptides often possess pronounced bioactivity. Their mass spectrometric characterization is difficult due to the predominant occurrence of non-proteinogenic monomers and the complex fragmentation patterns observed. Even though
Timo H J Niedermeyer, Martin Strohalm
doaj   +1 more source

Bright Side of Fusarium oxysporum: Secondary Metabolites Bioactivities and Industrial Relevance in Biotechnology and Nanotechnology

Journal of Fungi, 2021
Fungi have been assured to be one of the wealthiest pools of bio-metabolites with remarkable potential for discovering new drugs. The pathogenic fungi, Fusarium oxysporum affects many valuable trees and crops all over the world, producing wilt.
Sabrin R. M. Ibrahim, Alaa Sirwi, Basma G. Eid, Shaimaa G. A. Mohamed, Gamal A. Mohamed   +4 more
doaj   +1 more source

Stereocalpin B, a New Cyclic Depsipeptide from the Antarctic Lichen Ramalina terebrata

Metabolites, 2022
Stereocalpin B, a new cyclic depsipeptide (1), and a new dibenzofuran derivative (3), were isolated from the Antarctic lichen, Ramalina terebrata (Ramalinaceae), along with a known cyclic depsipeptide (2).
Seulah Lee, Se Yun Jeong, Dieu Linh Nguyen, Jae Eun So, Ki Hyun Kim, Ji Hee Kim, Se Jong Han, Sung-Suk Suh, Jun Hyuck Lee, Ui Joung Youn   +9 more
doaj   +1 more source

Cyclic Octamer Peptoids: Simplified Isosters of Bioactive Fungal Cyclodepsipeptides

Molecules, 2018
Cyclic peptoids have recently emerged as an important class of bioactive scaffolds with unique conformational properties and excellent metabolic stabilities.
Assunta D’Amato, Giorgio Della Sala, Irene Izzo, Chiara Costabile, Yuichi Masuda, Francesco De Riccardis   +5 more
doaj   +1 more source

Virtual Prospection of Marine Cyclopeptides as Therapeutics by Means of Conceptual DFT and Computational ADMET

Pharmaceuticals, 2022
Bioactive peptides are chemical compounds created through the covalent bonding of amino acids, known as amide or peptide bonds. Due to their unusual chemistry and various biological effects, marine bioactive peptides have garnered considerable research ...
Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik   +2 more
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Metabolities from Marine Sponges of the Genus Callyspongia: Occurrence, Biological Activity, and NMR Data

Marine Drugs, 2021
The genus Callyspongia (Callyspongiidae) encompasses a group of demosponges including 261 described species, of which approximately 180 have been accepted after taxonomic reviews.
Lucas Hilário Nogueira de Sousa, Rusceli Diego de Araújo, Déborah Sousa-Fontoura, Fabrício Gava Menezes, Renata Mendonça Araújo   +4 more
doaj   +1 more source

Enhanced Ohmyungsamycin A Production via Adenylation Domain Engineering and Optimization of Culture Conditions

Frontiers in Microbiology, 2021
Ohmyungsamycins (OMSs) A and B are cyclic depsipeptides produced by marine Streptomyces strains, which are synthesized by a non-ribosomal peptide synthetase. Notably, OMS A exhibits more potent activity against Mycobacterium tuberculosis and human cancer
Eunji Kim, Young Eun Du, Yeon Hee Ban, Yern-Hyerk Shin, Dong-Chan Oh, Yeo Joon Yoon   +5 more
doaj   +1 more source

Two New Cyclic Depsipeptides from the Endophytic Fungus sp

Natural Product Communications, 2015
Two new cyclic depsipeptides, W493 C (1) and D (2), along with two known derivatives W493 A (3) and B (4) were obtained from the endophytic fungus Fusarium sp. isolated from the Mangrove plant Ceriops tagal.
Fang Lv, Georgios Daletos, Wenhan Lin, Peter Proksch   +3 more
doaj   +1 more source

Cyclodepsipeptides from Marine Sponges: Natural Agents for Drug Research

Marine Drugs, 2010
A number of natural products from marine sponges, such as cyclodepsipeptides, have been identified. The structural characteristics of this family of cyclic peptides include various unusual amino acid residues and unique N-terminal polyketide-derived ...
Rosa Lemmens-Gruber, Gowri Shankar Bagavananthem Andavan   +1 more
doaj   +1 more source

Isolation, Structure Elucidation and Biological Evaluation of Lagunamide D: A New Cytotoxic Macrocyclic Depsipeptide from Marine Cyanobacteria

Marine Drugs, 2019
Lagunamide D, a new cytotoxic macrocyclic depsipeptide, was discovered from a collection of marine cyanobacteria from Loggerhead Key in the Dry Tortugas, Florida.
Danmeng Luo, Masteria Y. Putra, Tao Ye, Valerie J. Paul, Hendrik Luesch   +4 more
doaj   +1 more source