Results 51 to 60 of about 3,689 (198)

Biomedical and therapeutic applications of biosurfactants [PDF]

, 2010
During the last years, several applications of biosurfactants with medical purposes have been reported. Biosurfactants are considered relevant molecules for applications in combating many diseases and as therapeutic agents due to their antibacterial ...
A. Bernheimer, A. Fiechter, A. Flasz, A. Singh, A.B. Moldes, A.L. Moyne, B. Angelova, B. Gan, C. Carrillo, C. Delden Van, C. Heinemann, C.G. Hoogmoed Van, C.L. Wang, C.N. Mulligan, D. Kitamoto, D. Kitamoto, D. Vollenbroich, D. Vollenbroich, D.J. Bidel, D.R. Mack, F. Ahimou, F. Besson, F. Ramisse, G. Reid, G. Reid, G. Reid, G. Reid, G. Reid, H. Isoda, H. Isoda, H. Itokawa, H. Sano, H.J. Busscher, H.J. Busscher, H.J. Busscher, I. Grangemard, I.M. Banat, I.M. Banat, I.M. Banat, I.N.A. Bogaert Van, J. Gerard, J. Im, J.D. Desai, J.D. Hamme Van, J.D. Sheppard, J.H. Im, J.R. Mireles, J.R. Wright, K. Das, K. Das, K. Jenny, K. Kim, K. Millsap, K. Mittenbuhler, L. Thimon, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, M. Benincasa, M. Konishi, M. Morikawa, M. Shibahara, M. Velraeds, M. Velraeds, M. Velraeds, M. Velraeds, M. Yakimov, N. G. Dehghan, N. Kosaric, N. Kosaric, N. Naruse, O.M.P. Rivera, P. Gotek, P. Singh, R. Maier, R. Makkar, R. Sen, R.M. Maier, R.T. Otto, S. Boris, S. Cameotra, S. Cameotra, S. Igarashi, S. Ito, S. Joshi, S. Lang, S. Lin, S. Lin, S. Mukherjee, T. I. Pratt, T. Kikuchi, T. Kikuchi, T. Neu, T. Nielsen, T. Sudo, V. Shah, X. Zhao, X. Zhao, Y. Inoh, Y. Inoh, Y. Ishigami, Y. Kameda, Y. Maitani, Y. Tanaka, Y. Uchida, Y. Uchida, Y. Ueno, Y. Ueno, Y. Wakamatsu   +114 more
core   +1 more source

Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A

Angewandte Chemie International Edition, EarlyView.
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham, Edward S. Hems, Daniel C. L. Van, Justin E. Clarke, Sergey Nepogodiev, Julius S. P. Adamson, Christian Bassi, Michael E. Webb, Glyn R. Hemsworth, Orde Q. Munro, Barrie Wilkinson, Ryan F. Seipke   +11 more
wiley   +1 more source

Selective complexation of divalent cations by a cyclic α,β-peptoid hexamer: a spectroscopic and computational study [PDF]

, 2016
We describe the qualitative and quantitative analysis of the complexation properties towards cations of a cyclic peptoid hexamer composed of alternating α- and β-peptoid monomers, which bear exclusively chiral (S)-phenylethyl side chains (spe) that have ...
A. A. Edwards, A.-S. Biesse-Martin, Armand, Arnaud-Neu, B. D. Alexander, B. V. Nielsen, Baskin, Baskin, Baskin, Bosque-Sendra, C. Taillefumier, Caumes, Conti, Culf, Culf, D. Mistry, Daily, De Cola, De Cola, De Santis, De Santis, Della Sala, Devarajan, Diamond, Dudek, Durán Merás, E. De Santis, Eberspaecher, G. Siligardi, Gorske, Goutelle, Han, Hinaje, Hioki, Hjelmgaard, Izzo, Javorfi, Kalugin, Kelly, Kirshenbaum, Knight, Knight, L. Waters, Lee, Maayan, Maayan, Maharani, Maulucci, Mishustin, Ovchinnikov, Pigot, R. Hussain, Roy, S. Faure, S. J. Holder, Schettini, Shannon, Shin, Siligardi, Siligardi, Stewart, Sui, Wu, Wu, Yoe, Yoo, Zabrodski, Zeng, Zsila   +68 more
core   +2 more sources

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Cyclic peptides and depsipeptides from cyanobacteria: A review

Journal of Industrial Microbiology, 1996
An elaborate array of structurally-novel and biologically-active cyclic peptides and depsipeptides are found in blue-green algae (cyanobacteria). Several of these compounds possess structures that are similar to those of natural products from marine invertebrates.
openaire   +2 more sources

Investigation of the N-Terminus Amino Function of Arg10-Teixobactin

Molecules, 2017
Teixobactin is a recently described antimicrobial peptide that shows high activity against gram-positive bacteria as well as mycobacterium tuberculosis.
Shimaa A. H. Abdel Monaim, Sikabwe Noki, Estelle J. Ramchuran, Ayman El-Faham, Fernando Albericio, Beatriz G. de la Torre   +5 more
doaj   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Biosurfactants: potential applications in medicine [PDF]

, 2006
The use and potential commercial application of biosurfactants in the medical field has increased during the past decade. Their antibacterial, antifungal and antiviral activities make them relevant molecules for applications in combating many diseases ...
Banat, Ibrahim M., Oliveira, Rosário, Rodrigues, L. R., Teixeira, J. A.   +3 more
core   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source