Results 231 to 240 of about 1,721,329 (334)

Quadratic unconstrained binary optimization and constraint programming approaches for lattice-based cyclic peptide docking. [PDF]

Sci Rep
Brubaker JK, Booth KEC, Arakawa A, Furrer F, Ghosh J, Sato T, Katzgraber HG.   +6 more
europepmc   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Targeted imaging of pulmonary fibrosis by a cyclic peptide LyP-1. [PDF]

Sci Rep
Li J, Shu R, Peng T, Yang Z, Yang M, Hu F, Tao Z, Hong Y, Cai Z, Jia J, Wan L, Tian S, She ZG, Li H, Zhang XJ, Zhang E.   +15 more
europepmc   +1 more source

Photoactivated Proximity Protein Labeling Reveals Enhanced Tumor Retention of a D‐Peptide‐Ruthenium Prodrug Conjugate

Advanced Healthcare Materials, EarlyView.
Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang, Peiyuan Wang, Hildert Bronkhorst, Yurii Husiev, Ludovic Bretin, Maarten N. van Ginkel, Wen Sun, Sylvestre Bonnet   +7 more
wiley   +1 more source

Ultra-short cyclic peptide Cy _RL-QN15 acts as a TLR4 antagonist to expedite oral ulcer healing. [PDF]

Zool Res
Ru ZQ, Wu YT, Yang CY, Yang YT, Li YJ, Liu M, Peng Y, Yang YL, Wang JY, Jia QY, Li YS, Fu Z, Yang MF, Tang J, Fan Y, Liu CX, Su WR, Liu NX, He L, Wang Y, Yang XW.   +20 more
europepmc   +1 more source

Silencing Myostatin Using In Vivo Self‐Assembled siRNA Protects Against Cancer‐ and Dexamethasone‐Induced Muscle Atrophy

Advanced Healthcare Materials, EarlyView.
This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin, Azhar Anwar, Jiehao Chen, Qinghao Sun, Likun Zhou, Jie Tang, Jingwei Guo, Linbo Yan, Yongci Chen, Feng Yin, Chen‐Yu Zhang, Zigang Li, Jizheng Ma, Liyuan Sheng, Xi Chen   +14 more
wiley   +1 more source

A novel homoarginine-containing cyclic peptide pioamide with selective antipseudomonal activity isolated from the nematode symbiont <i>Photorhabdus khanii</i>. [PDF]

Appl Environ Microbiol
Imai Y, Son S, Sasaki M, Liang L, Gates MF, Ghiglieri M, Shimosato T, Honrao C, Ma X, Guo JJ, Lewis K.   +10 more
europepmc   +1 more source

Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS‐CoV‐2 Main Protease with Antiviral Activity [PDF]

K. J. Harrison, Patrick W. Carlos, Sven Ullrich, Anupriya Aggarwal, Jason Johansen‐Leete, Vishnu Mini Sasi, Isabel Barter, Joshua W. C. Maxwell, Max J. Bedding, Mark Larance, Stuart Turville, Alexander Norman, Colin J. Jackson, Christoph Nitsche, Richard J. Payne   +14 more
openalex   +1 more source

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

A synthetic cyclic peptide for promoting antigen presentation and immune activation. [PDF]

NPJ Vaccines
Zhang J, Madge HYR, Mahmoud A, Lu L, Wang W, Huang W, Koirala P, Gonzalez Cruz JL, Kong WY, Bashiri S, Shalash AO, Hussein WM, Khalil ZG, Wells JW, Toth I, Stephenson RJ.   +15 more
europepmc   +1 more source