Results 271 to 280 of about 504,196 (405)

PD‐L1 Expression is Mediated by microRNA Processing, Wnt/β‐Catenin Signaling, and Chemotherapy in Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Inhibition of immune checkpoint proteins is effective in adult cancers but has shown limited efficacy in pediatric cancers. While factors regulating expression of immune checkpoint proteins such as PD‐L1 are well documented in adult cancers, their regulation is poorly understood in pediatric cancers.
Patricia D. B. Tiburcio, Kavita Desai, Austin Warne, Arash Nabbi, Serena Zhou, Sean D. Reiff, Matthew E. Campbell, James F. Amatruda, Kenneth S. Chen   +8 more
wiley   +1 more source

Identification of novel cyclin-dependent kinase 4/6 inhibitors from marine natural products. [PDF]

PLoS One
Debnath A, Mazumder R, Singh AK, Singh RK.   +3 more
europepmc   +1 more source

Genetic framework of cyclin-dependent kinase function in Arabidopsis.

Developmental Cell, 2012
Moritz K. Nowack, Hirofumi Harashima, Nico Dissmeyer, Xin’Ai Zhao, D. Bouyer, Annika K. Weimer, Freya De Winter, Fang Yang, A. Schnittger   +8 more
semanticscholar   +1 more source

Covalent Inhibition of the Peptidyl‐Prolyl Isomerase Pin1 by Sulfopin Results in a Broad Impact on the Phosphoproteome of Human Osteosarcoma U2‐OS Cells

PROTEOMICS, EarlyView.
ABSTRACT Peptidyl‐prolyl isomerase, NIMA‐interacting protein 1‐(Pin1) catalyses the cis–trans interconversion of the inflexible bond between serine or threonine residues and proline at the +1 position (pSer/pThr‐Pro). Although initially discovered as an essential regulator of cell division, Pin1 has since been identified as a regulator of many ...
Scott E. Roffey, Owen Hovey, Kristina Jurcic, Kun Ping Lu, Xiao Zhen Zhou, David W. Litchfield   +5 more
wiley   +1 more source

Cyclin-dependent kinase 5 (CDK5) inhibitors in Parkinson disease. [PDF]

J Cell Mol Med
Alrouji M, Al-Kuraishy HM, Al-Gareeb AI, Alshammari MS, Alexiou A, Papadakis M, Bahaa MM, Batiha GE.   +7 more
europepmc   +1 more source

A sejtek osztódásának aktiválásában és szabályozásában szerepet játszó fehérjék lucernában [PDF]

, 2008
Miskolczi Pál
core  

P53 and anti‐p53 autoantibody complex versus anti‐p53 antibody as a biomarker for gastrointestinal cancer

Precision Medical Sciences, EarlyView.
This study compares the diagnostic value of the anti‐p53 autoantibody as potential biomarkers for gastrointestinal cancer with enzyme‐linked immunosorbent assay technique. Abstract Gastrointestinal tract cancer is among the most common types of cancer and includes colorectal cancer (CRC) and gastric cancer (GC).
V. Hamidi Sofiani, A. Ebrahimian Shiadeh, A. Tabarraei, H. Razavi Nikoo, F. Sadeghi, Gh. Kamrani, Y. Yahyapour, A. Moradi   +7 more
wiley   +1 more source

Phase I first-in-human dose escalation study of the oral casein kinase 1α and cyclin dependent kinase 7/9 inhibitor BTX A51 in advanced MDS and AML. [PDF]

J Hematol Oncol
Ball BJ, Xiao W, Borthakur G, Nguyen LXT, Valerio M, Venkatachalam A, Marcucci G, Stein AS, Thai DL, Cook DN, Chan K, Persaud S, Levine RL, Abdel-Wahab O, Ben-Neriah Y, Stein EM.   +15 more
europepmc   +1 more source

Phytoestrogen Signal Pathways and Estrogen Signaling in Ovarian Cancer: A Narrative Review

Phytotherapy Research, EarlyView.
Phytoestrogen signal pathways targeted in ovarian cancer. ABSTRACT Ovarian cancer (OC) is the second most common gynecological cancer and the leading cause of death from gynecological malignancies. Ovarian cancer mortality rate ranks fifth among cancer‐related deaths in Western societies.
Ozgur Kutuk, Ayse Kaplan
wiley   +1 more source

Cyclin-dependent kinase 5 (Cdk5) activity is modulated by light and gates rapid phase shifts of the circadian clock. [PDF]

Elife
Brenna A, Borsa M, Saro G, Ripperger JA, Glauser DA, Yang Z, Adamantidis A, Albrecht U.   +7 more
europepmc   +1 more source