Results 1 to 10 of about 76,308 (284)

Cell cycle progression or translation control is not essential for vesicular stomatitis virus oncolysis of hepatocellular carcinoma. [PDF]

, 2010
The intrinsic oncolytic specificity of vesicular stomatitis virus (VSV) is currently being exploited to develop alternative therapeutic strategies for hepatocellular carcinoma (HCC). Identifying key regulators in diverse transduction pathways that define
A Bianchini, A Villanueva, Alexandra Junger, Antonia Rizzani, DA Altomare, EF Dunn, Enrico N. De Toni, Günter Schneider, HG Wendel, I Fabregat, I Nicoletti, IBCJ Rosenwald, JE Dancey, Jennifer Altomonte, JH Connor, JS Orlando, K Shinozaki, K Shinozaki, L Mishra, LM Schang, M Ahmed, M Hidalgo, M Ikeda, M Sun, Maciej Lesniak, N Kato, N Kato, N Kemeny, N Sonenberg, NA Hamid, Nobuyuki Kato, O Ebert, O Ebert, O Larsson, Oliver Ebert, P Chakraborty, P Newell, PC Chiang, PL Hallenbeck, RB Kjellerup, RL Silva, RM Memmott, Roland M. Schmid, S Balachandran, S Joshi, S Marozin, S Oliere, S Sei, S Sell, Sabrina Marozin, SM Steinberg, SR Kimball, T Cascone, T Nakamura, T Ueda, TL Nguyen, TP Cripe, WE Thasler, Wolfgang E. Thasler, XQ Lun, Y Ma   +60 more
core   +23 more sources

Research progress on cell cycle regulation-related molecules in the development of oral squamous cell carcinoma

Kouqiang hemian waike zazhi, 2023
Oral squamous cell carcinoma (OSCC) is the most common oral and maxillofacial cancer. In‐depth research on the regulatory mechanism of cell cycle regulation‐related molecules has revealed that these molecules play various roles in the incidence and ...
HOU Zeyu, TANG Jinru, LI Longjiang
doaj   +1 more source

A review on the role of cyclin dependent kinases in cancers

Cancer Cell International, 2022
The Cyclin-dependent kinase (CDK) class of serine/threonine kinases has crucial roles in the regulation of cell cycle transition and is mainly involved in the pathogenesis of cancers.
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Peixin Dong, Nikolaus Gassler, Mohammad Taheri, Aria Baniahmad, Nader Akbari Dilmaghani   +7 more
doaj   +1 more source

Multiple cutaneous melanomas associated with gastric and brain metastases [PDF]

Anais Brasileiros de Dermatologia, 2016
The occurrence of multiple primary melanomas in a single individual is rare. Most commonly, malignant melanocytic lesions subsequent to the initial diagnosis of melanoma are secondary cutaneous metastases.
Lara Caroline Grander, Fernanda Cabral, Alice Paixão Lisboa, Gabrielle Vale, Carlos Baptista Barcaui, Juan Manuel Pineiro Maceira   +5 more
doaj   +1 more source

EmCyclinD-EmCDK4/6 complex is involved in the host EGF-mediated proliferation of Echinococcus multilocularis germinative cells via the EGFR-ERK pathway

Frontiers in Microbiology, 2022
The larval stage of the tapeworm Echinococcus multilocularis causes alveolar echinococcosis (AE), one of the most lethal helminthic infections in humans.
Chonglv Feng, Chonglv Feng, Zhe Cheng, Zhe Cheng, Zhijian Xu, Zhijian Xu, Ye Tian, Ye Tian, Huimin Tian, Fan Liu, Damin Luo, Damin Luo, Yanhai Wang, Yanhai Wang   +13 more
doaj   +1 more source

Cyclin-dependent kinases and rare developmental disorders

Orphanet Journal of Rare Diseases, 2020
Extensive studies in the past 30 years have established that cyclin-dependent kinases (CDKs) exert many diverse, important functions in a number of molecular and cellular processes that are at play during development.
Pierre Colas
doaj   +1 more source

In Silico and Cellular Differences Related to the Cell Division Process between the A and B Races of the Colonial Microalga Botryococcus braunii

Biomolecules, 2021
Botryococcus braunii produce liquid hydrocarbons able to be processed into combustion engine fuels. Depending on the growing conditions, the cell doubling time can be up to 6 days or more, which is a slow growth rate in comparison with other microalgae ...
Xochitl Morales-de la Cruz, Alejandra Mandujano-Chávez, Daniel R. Browne, Timothy P. Devarenne, Lino Sánchez-Segura, Mercedes G. López, Edmundo Lozoya-Gloria   +6 more
doaj   +1 more source

Deciphering the modes of human separase inhibition by securin and CDK1-CCNB1

Molecular & Cellular Oncology, 2021
Accurate chromosome segregation depends on tight regulation of the protease separase, which cleaves the ring-shaped cohesin complex that entraps the two sister chromatids.
Pierre Raia, Jun Yu, Andreas Boland
doaj   +1 more source

CDKs family -a glimpse into the past and present: from cell cycle control to current biological functions

Asian Pacific Journal of Cancer Biology, 2020
Cyclin-dependent kinases (CDKs) are the catalytic subunits or protein kinases characterized by separate subunit “cyclin” that are essential for their enzymatic activity.
Muzna Shah, Muhammad Fazal Hussain Qureshi, Danish Mohammad, Mahira Lakhani, Tabinda Urooj, Shamim Mushtaq   +5 more
doaj   +1 more source

Targeting Protein-Protein Interactions to Inhibit Cyclin-Dependent Kinases

Pharmaceuticals, 2023
Cyclin-dependent kinases (CDKs) play diverse and critical roles in normal cells and may be exploited as targets in cancer therapeutic strategies. CDK4 inhibitors are currently approved for treatment in advanced breast cancer.
Mark Klein
doaj   +1 more source